[1]邱颖谦,陈永林.微小RNA在肝细胞肝癌中的作用研究进展[J].新乡医学院学报,2020,37(9):893-896.[doi:10.7683/xxyxyxb.2020.09.021]
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微小RNA在肝细胞肝癌中的作用研究进展
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《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
37
期数:
2020年9
页码:
893-896
栏目:
综述
出版日期:
2020-09-05

文章信息/Info

作者:
邱颖谦123陈永林23
(1.兰州大学第一临床医学院,甘肃 兰州 730000;2.兰州大学第一医院病理科,甘肃 兰州 730000;3.兰州大学第一医院病理学研究所,甘肃 兰州 730000)
关键词:
肝细胞肝癌微小RNA治疗
分类号:
R73
DOI:
10.7683/xxyxyxb.2020.09.021
文献标志码:
A
摘要:
肝细胞肝癌是一种高病死率的原发性肝癌,目前的诊断和治疗方法具有局限性。研究发现,微小RNA(miRNA)参与生物个体发育、细胞增殖与分化、肿瘤细胞的发生发展等多种病理过程,并调控致癌基因与抑癌基因的表达。大量研究表明,miRNAs在肝细胞肝癌中异常表达,其可能成为诊断肝细胞肝癌新的生物标志物及治疗靶点。本文对近年来miRNAs在肝细胞肝癌中的研究进展进行综述。

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更新日期/Last Update: 2020-09-05