[1]张高丽,邓予晖,王晓宇,等.外泌体微小核糖核酸在心肌梗死诊断及干细胞治疗中的研究进展[J].新乡医学院学报,2020,37(9):890-892.[doi:10.7683/xxyxyxb.2020.09.020]
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外泌体微小核糖核酸在心肌梗死诊断及干细胞治疗中的研究进展
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《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
37
期数:
2020年9
页码:
890-892
栏目:
综述
出版日期:
2020-09-05

文章信息/Info

作者:
张高丽邓予晖王晓宇李雅欣赵文心许泼实
(河南省人民医院检验科,阜外华中心血管病医院检验科,郑州大学阜外华中心血管病医院, 河南 郑州 450000)
关键词:
外泌体微小核糖核酸心肌梗死干细胞治疗
分类号:
R54
DOI:
10.7683/xxyxyxb.2020.09.020
文献标志码:
A
摘要:
心肌梗死是严重威胁人类健康的心血管疾病之一,它是由于冠状动脉急性、持续性的缺血缺氧所引起的心肌坏死。外泌体是由多囊泡体与细胞膜融合形成的直径30~200 nm的膜性小囊泡。具有细胞间通信功能,能刺激免疫应答,参与抗原呈递、免疫反应、细胞增殖等多种生理过程的调控。外泌体是微小核糖核酸(miRNA)的富集体,miRNA在外泌体双层脂质膜的保护下更能稳定表达,外泌体miRNA参与心血管疾病的病理生理过程,并在心肌梗死患者的诊断、预后、治疗中具有重要价值。本文就外泌体miRNA在心肌梗死诊断和干细胞治疗中的意义作一综述。

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更新日期/Last Update: 2020-09-05