[1]罗和生,万一圆,黄晓东.微小RNA在恶性肿瘤诊断与治疗中的研究进展[J].新乡医学院学报,2018,35(12):1134-1138.[doi:10.7683/xxyxyxb.2018.12.023]
 N/A.N/A[J].Journal of Xinxiang Medical University,2018,35(12):1134-1138.[doi:10.7683/xxyxyxb.2018.12.023]
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微小RNA在恶性肿瘤诊断与治疗中的研究进展
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《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
35
期数:
2018年12
页码:
1134-1138
栏目:
综述
出版日期:
2018-12-05

文章信息/Info

Title:
N/A
作者:
罗和生1万一圆1黄晓东2
(1.武汉大学人民医院消化内科,湖北 武汉 430060;2.武汉大学附属同仁医院消化内科,湖北 武汉 430060)
Author(s):
N/A
N/A
关键词:
微小RNA肿瘤诊断治疗
Keywords:
N/A
分类号:
R73-3
DOI:
10.7683/xxyxyxb.2018.12.023
文献标志码:
A
摘要:
微小RNA(miRNA)是一类普遍存在于多种生物体内的长度为21~25个核苷酸的内源性单链非编码小分子RNA,通过靶向降解信使 RNA(mRNA) 或抑制mRNA翻译参与个体发育及细胞增殖、分化、凋亡等一系列重要生物学进程,与人类多种疾病(包括肿瘤性疾病、心血管疾病、内分泌疾病、感染性疾病、自身免疫性疾病、神经变性疾病等)的发生、发展密切相关。其中,miRNA在人类不同肿瘤中可能作为潜在的癌基因或抑癌基因发挥作用。为深入研究miRNA与人类肿瘤的关系,本文就miRNA参与肿瘤发病的机制以及miRNA在肿瘤诊断、预后评估和治疗等方面的相关研究加以综述,以期为临床早期诊断及治疗恶性肿瘤提供新的思路。
Abstract:
N/A

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更新日期/Last Update: 2018-12-05