[1]彭 馨,杨 鹏,马武开,等.外泌体在干燥综合征诊断和治疗中的应用研究进展[J].新乡医学院学报,2022,39(6):589-592.[doi:10.7683/xxyxyxb.2022.06.018]
 PENG Xin,YANG Peng,MA Wukai,et al.Research progress on the application of exosomes in the diagnosis and treatment of Sj?gren′s syndrome[J].Journal of Xinxiang Medical University,2022,39(6):589-592.[doi:10.7683/xxyxyxb.2022.06.018]
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外泌体在干燥综合征诊断和治疗中的应用研究进展
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《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
39
期数:
2022年6
页码:
589-592
栏目:
综述
出版日期:
2022-06-05

文章信息/Info

Title:
Research progress on the application of exosomes in the diagnosis and treatment of Sj?gren′s syndrome
作者:
彭 馨1杨 鹏2马武开2曾 苹2
(1.贵州中医药大学研究生院,贵州 贵阳 550002;2.贵州中医药大学第二附属医院风湿免疫科,贵州 贵阳 550002)
Author(s):
PENG Xin1YANG Peng2MA Wukai2ZENG Ping2
(1.Graduate School,Guizhou University of Traditional Chinese Medicine,Guiyang 550002,Guizhou Province,China;2.Department of Rheumatology and Immunology,the Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine,Guiyang 550002,Guizhou Province,China)
关键词:
干燥综合征外泌体诊断治疗
Keywords:
Sj?gren′s syndromeexosomesdiagnosistreatment
分类号:
R442.8
DOI:
10.7683/xxyxyxb.2022.06.018
文献标志码:
A
摘要:
干燥综合征(SS)是一种以淋巴细胞浸润外分泌腺为主要特征的自身免疫性疾病。目前,SS的病理机制尚未完全清楚,其诊断和治疗水平也不能满足临床需要。外泌体含有疾病状态下许多重要的信息物质,几乎参与所有疾病的病理过程,包括癌症、感染和自身免疫性疾病等,能够反映疾病的真实情况,在免疫细胞活化、免疫应答及免疫调节中发挥着重要作用;因此,开展外泌体的研究有望为阐明SS的发病机制、提高其诊断和治疗水平提供新的视角。本文旨在对外泌体在SS病理机制、诊断和治疗中的作用研究进展进行综述。
Abstract:
Sj?gren′s syndrome (SS) is an autoimmune disease characterized by lymphocyte infiltrating into exocrine glands.At present,the pathological mechanism of SS is not completely clear,and its diagnosis and treatment level cannot meet clinical needs.Exosomes contains many important information materials in the disease state,and it almostly participates in the pathological process of all diseases,including cancer,infection and autoimmune diseases.It plays a key role in immune cell activation,immune response and immune regulation.Therefore,research on exosomes is expected to provide a new perspective for clarifying the pathogenesis of SS and improving the diagnosis and treatment level for SS.This paper aims to review the research progress of the role of exosomes in the pathological mechanism,diagnosis and treatment of SS.

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更新日期/Last Update: 2022-06-05