[1]张　锐,孟玉娇,冯继伟,等.大气颗粒物暴露对呼吸道病毒感染的影响研究进展[J].新乡医学院学报,2022,39(6):593-595.[doi:10.7683/xxyxyxb.2022.06.019]
　ZHANG Rui,MENG Yujiao,FENG Jiwei,et al.Research progress on the effect of particulate matter exposure on respiratory virus infections[J].Journal of Xinxiang Medical University,2022,39(6):593-595.[doi:10.7683/xxyxyxb.2022.06.019]
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大气颗粒物暴露对呼吸道病毒感染的影响研究进展
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《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
39
期数:
2022年6
页码:
593-595
栏目:
综述
出版日期:
2022-06-05

文章信息/Info

Title:
Research progress on the effect of particulate matter exposure on respiratory virus infections
作者:
张　锐; 孟玉娇; 冯继伟; 王寅彪; 吴卫东
（新乡医学院公共卫生学院，河南　新乡　453003）
Author(s):
ZHANG Rui; MENG Yujiao; FENG Jiwei; WANG Yinbiao; WU Weidong
(School of Public Health,Xinxiang Medical University,Xinxiang 453003,Henan Province,China)
关键词:
大气颗粒物; 呼吸道病毒感染; 相互作用; 机制
Keywords:
particulate matter; respiratory viral infections; interactions; mechanism
分类号:
R122
DOI:
10.7683/xxyxyxb.2022.06.019
文献标志码:
A
摘要:
大气颗粒物（PM）暴露与人群呼吸道病毒性传染病的发病率和病死率存在相关性。呼吸道是PM暴露和呼吸道病毒感染的共同作用场所。PM可影响呼吸道病毒感染进程及病毒性疾病的严重程度，病毒感染可加重PM诱发的呼吸道疾病。在流行病学基础上，开展PM暴露与呼吸道病毒感染相互作用的毒理学研究对于提出干预措施降低相关疾病的发病率和病死率具有重要意义。本文根据国内外流行病学研究和毒理学研究结果对PM影响呼吸道病毒感染的过程和机制进行总结，以期为相关研究提供参考。
Abstract:
Particulate matter (PM) exposure is associated with the incidence and morbidity of respiratory viral infectious diseases in the populations.The respiratory tract is a common target site for PM exposure and respiratory viral infection.The progression of respiratory viral infection and the severity of viral diseases can be influenced by PM,and viral infections can aggravate PM-induced respiratory diseases.On the basis of epidemiology studies,carrying out toxicological study on the interaction between PM and respiratory viruses had important significance for proposing interventions measures to reduce the incidence and morbidity of related diseases.Based on the results of epidemiological studies and toxicological studies at home and abroad,this paper summarizes the process and mechanism of PM affecting respiratory virus infection in order to provide reference for related studies.

参考文献/References:

［1］　 LOAIZA-CEBALLOS M C,MARIN-PALMA D,ZAPATA W,et al.Viral respiratory infections and air pollutants［J］.Air Qual Atmos Health,2021,Epub ahead of print.
［2］　WANG C C,PRATHER K A,SZNITMAN J,et al.Airborne transmission of respiratory viruses［J］.Science,2021,373(6558):eabd9149.
［3］　ZHANG Y,LANG J,CHENG S,et al.Chemical composition and sources of PM1 and PM2.5 in Beijing in autumn［J］.Sci Total Environ,2018,630:72-82.
［4］　XING Y F,XU Y H,SHI M H,et al.The impact of PM2.5 on the human respiratory system［J］.J Thorac Dis,2016,8(1):e69-e74.
［5］　HORNE B D,JOY E A,HOFMANN M G,et al.Short-term elevation of fine particulate matter air pollution and acute lower respiratory infection［J］.Am J Respir Crit Care Med,2018,198(6):759-766.
［6］　POPE C A 3rd,COLEMAN N,POND Z A,et al.Fine particulate air pollution and human mortality:25+ years of cohort studies［J］.Environ Res,2020,183:108924.
［7］　LOSACCO C,PERILLO A.Particulate matter air pollution and respiratory impact on humans and animals［J］.Environ Sci Pollut Res Int,2018,25(34):33901-33910.
［8］　ZHANG Z,CHAI P,WANG J,et al.Association of particulate matter air pollution and hospital visits for respiratory diseases:a time-series study from China［J］.Environ Sci Pollut Res Int,2019,26(12):12280-12287.
［9］　LIANG F,LIU F,HUANG K,et al.Long-term exposure to fine particulate matter and cardiovascular disease in China［J］.J Am Coll Cardiol,2020,75(7):707-717.
［10］　BOURDREL T,BIND M A,BJOT Y,et al.Cardiovascular effects of air pollution［J］.Arch Cardiovasc Dis,2017,110(11):634-642.
［11］　YOUNAN D,PETKUS A J,WIDAMAN K F,et al.Particulate matter and episodic memory decline mediated by early neuroanatomic biomarkers of Alzheimer′s disease［J］.Brain,2020,143(1):289-302.
［12］　LIU X,JIN X,SU R,et al.The reproductive toxicology of male SD rats after PM2.5 exposure mediated by the stimulation of endoplasmic reticulum stress［J］.Chemosphere,2017,189:547-555.
［13］　XUE T,ZHANG Q.Associating ambient exposure to fine particles and human fertility rates in China［J］.Environ Pollut,2018,235:497-504.
［14］　MELODY S M,FORD J,WILLS K,et al.Maternal exposure to short-to medium-term outdoor air pollution and obstetric and neonatal outcomes:a systematic review［J］.Environ Pollut,2019,244:915-925.
［15］　KIM B E,KIM J,GOLEVA E,et al.Particulate matter causes skin barrier dysfunction［J］.JCI Insight,2021,6(5):e145185.
［16］　CROFT D P,ZHANG W,LIN S,et al.The association between respiratory infection and air pollution in the setting of air quality policy and economic change［J］.Ann Am Thorac Soc,2019,16(3):321-330.
［17］　GUO J,MA M,XIAO C,et al.Association of air pollution and mortality of acute lower respiratory tract infections in Shenyang,China:a time series analysis study［J］.Iran J Public Health,2018,47(9):1261-1271.
［18］　ZHENG P W,WANG J B,ZHANG Z Y,et al.Air pollution and hospital visits for acute upper and lower respiratory infections among children in Ningbo,China:a time-series analysis［J］.Environ Sci Pollut Res Int,2017,24(23):18860-18869.
［19］　XIA X,ZHANG A,LIANG S,et al.The association between air pollution and population health risk for respiratory infection:a case study of Shenzhen,China［J］.Int J Environ Res Public Health,2017,14(9):950.
［20］　WU X,NETHERY R C,SABATH M B,et al.Air pollution and COVID-19 mortality in the United States:strengths and limitations of an ecological regression analysis［J］.Sci Adv,2020,6(45):eabd4049.
［21］　YAO Y,PAN J,LIU Z,et al.Temporal association between particulate matter pollution and case fatality rate of COVID-19 in Wuhan［J］.Environ Res,2020,189:109941.
［22］　YAO Y,PAN J,WANG W,et al.Association of particulate matter pollution and case fatality rate of COVID-19 in 49 Chinese cities［J］.Sci Total Environ,2020,741:140396.
［23］　SETTI L,PASSARINI F,DE GENNARO G,et al.Searching for SARS-COV-2 on particulate matter:a possible early indicator of COVID-19 epidemic recurrence［J］.Int J Environ Res Public Health,2020,17(9):2986.
［24］　CRUZ-SANCHEZ T M,HADDRELL A E,HACKETT T L,et al.Formation of a stable mimic of ambient particulate matter containing viable infectious respiratory syncytial virus and its dry-deposition directly onto cell cultures［J］.Anal Chem,2013,85(2):898-906.
［25］　YANG B,GUO J,XIAO C.Effect of PM2.5 environmental pollution on rat lung［J］.Environ Sci Pollut Res Int,2018,25(36):36136-36146.
［26］　MISHRA R,KRISHNAMOORTHY P,GANGAMMA S,et al.Particulate matter (PM10) enhances RNA virus infection through modulation of innate immune responses［J］.Environ Pollut,2020,266(Pt 1):115148.
［27］　TAO R J,CAO W J,LI M H,et al.PM2.5 compromises antiviral immunity in influenza infection by inhibiting activation of NLRP3 inflammasome and expression of interferon-β［J］.Mol Immunol,2020,125:178-186.
［28］　XIAO T,LING M,XU H,et al.NF-κB-regulation of miR-155,via SOCS1/STAT3,is involved in the PM2.5-accelerated cell cycle and proliferation of human bronchial epithelial cells［J］.Toxicol Appl Pharmacol,2019,377:114616.
［29］　REBULI M E,SPEEN A M,MARTIN E M,et al.Wood smoke exposure alters human inflammatory responses to viral infection in a sex-specific manner［J］.Am J Respir Crit Care Med,2019,199(8):996-1007.
［30］　LIN C I,TSAI C H,SUN Y L,et al.Instillation of particulate matter 2.5 induced acute lung injury and attenuated the injury recovery in ACE2 knockout mice［J］.Int J Biol Sci,2018,14(3):253-265.
［31］　WANG B,CHEN H,CHAN Y L,et al.Is there an association between the level of ambient air pollution and COVID-19［J］.Am J Physiol Lung Cell Mol Physiol,2020,319(3):L416-L421.
［32］　KIM J H,KIM J,KIM W J,et al.Diesel particulate matter 2.5 induces epithelial-to-mesenchymal transition and upregulation of SARS-CoV-2 receptor during human pluripotent stem cell-derived alveolar organoid development［J］.Int J Environ Res Public Health,2020,17(22):8410.

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更新日期/Last Update: 2022-06-05