[1]樊松强,魏金星.直肠超声引导下经会阴与经直肠前列腺穿刺活检效果比较[J].新乡医学院学报,2017,34(3):197-199.[doi:10.7683/xxyxyxb.2017.03.010]
　FAN Song-qiang,WEI Jin-xing.Comparison of the effect of transperineal and transrectal prostate puncture biopsy guided by transrectal ultrasonography[J].Journal of Xinxiang Medical University,2017,34(3):197-199.[doi:10.7683/xxyxyxb.2017.03.010]
点击复制

直肠超声引导下经会阴与经直肠前列腺穿刺活检效果比较
分享到：

《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
34
期数:
2017年3
页码:
197-199
栏目:
临床研究
出版日期:
2017-03-05

文章信息/Info

Title:
Comparison of the effect of transperineal and transrectal prostate puncture biopsy guided by transrectal ultrasonography
作者:
樊松强1; 魏金星2
（1.漯河市第二人民医院泌尿外科，河南　漯河　462000；2.郑州大学第一附属医院泌尿外科，河南　郑州　450000）
Author(s):
FAN Song-qiang1; WEI Jin-xing2
（1.Department of Urology Surgery，the Second People′s Hospital of Luohe City，Luohe 462000，Henan Province，China；2.Department of Urology Surgery，the First Affiliated Hospital of Zhengzhou University，Zhengzhou 450000，Henan Province，China）
关键词:
前列腺癌; 经直肠穿刺; 经会阴穿刺; 前列腺穿刺活检
Keywords:
prostate cancer; transrectal puncture; transperineal puncture; prostate puncture biopsy
分类号:
R737.25
DOI:
10.7683/xxyxyxb.2017.03.010
文献标志码:
A
摘要:
目的　比较直肠超声引导下经会阴与经直肠前列腺穿刺活检的临床效果。方法　选取2014年1月至2016年5月于漯河市第二人民医院行前列腺穿刺活检患者117例，其中经会阴穿刺58例（经会阴穿刺组），经直肠穿刺59例（经直肠穿刺组），对2组患者的前列腺穿刺活检结果及穿刺相关并发症进行比较。结果　经会阴穿刺组58例患者前列腺穿刺病理检查结果为前列腺癌18例（31.03%）、慢性前列腺炎16例（27.59%）、良性前列腺增生24例（41.38%），经直肠穿刺组59例患者前列腺穿刺病理检查结果为前列腺癌20例（33.90%）、慢性前列腺炎17例（28.81%）、良性前列腺增生22例（37.29%），2组患者前列腺穿刺病理检查结果比较差异无统计学意义（P>0.05）。经会阴穿刺组患者发热、血尿、血便、尿路感染、尿路刺激征、会阴肿胀和尿潴留发生率分别为3.45%（2/58）、8.62%（6/58）、1.72%（1/58）、3.45%（2/58）、3.45%（2/58）、6.90%（4/58）和3.45%（2/58），经直肠穿刺组患者发热、血尿、血便、尿路感染、尿路刺激征、会阴肿胀和尿潴留发生率分别为10.17%（6/59）、10.17%（6/59）、16.95%（10/59）、15.25%（9/59）、3.39%（2/59）、0.00%（0/59）和1.69%（1/59）；经会阴穿刺组患者发热、血便及尿路感染发生率显著低于经直肠穿刺组（P<0.05），但会阴肿胀发生率显著高于直肠穿刺组（P<0.05）；2组患者血尿、尿路刺激征及尿潴留发生率比较差异均无统计学意义（P>0.05）；经会阴穿刺组和经直肠穿刺组患者总并发症发生率分别为31.03%（18/58）和57.63%（34/59），经会阴穿刺组患者总并发症发生率显著低于经直肠穿刺组（P<0.05）。结论　经会阴前列腺穿刺与经直肠前列腺穿刺活检结果相当，但经会阴前列腺穿刺相关并发症发生率低。
Abstract:
Objective　To compared the effect of transperineal and transrectal prostate puncture biopsy guided by transrectal ultrasonography.Methods　A total of 117 patients who underwent prostate puncture biopsy were selected in the Second People′s Hospital of Luohe City from January 2014 to May 2016.Among the patients，58 patients in transperineal prostate puncture biopsy group were performed with transperineal prostate puncture biopsy，and 59 patients in transrectal prostate puncture biopsy group were performed with transrectal prostate puncture biopsy.The results of prostate puncture biopsy and puncture-related complications were compared between the two groups.Results　The pathological results of the 58 cases in transperineal prostate puncture biopsy group were prostate cancer in 18 cases （31.03%），chronic prostatitis in 16 cases （27.59%） and benign prostatic hyperplasia in 24 cases （41.38%）.The pathological results of the 58 cases in transrectal prostate puncture biopsy group were prostate cancer in 20 cases （33.90%），chronic prostatitis in 17 cases （28.81%） and benign prostatic hyperplasia in 22 cases （37.29%）.There was no significant difference in the results of prostate biopsy between the two groups（P>0.05）.The incidence of fever，hematuria，bloody stool，urinary tract infection，urinary tract infection，urinary irritation symptoms，perineal swelling and urinary retention in transperineal prostate puncture biopsy group was 3.45%（2/58），8.62%（6/58），1.72%（1/58），3.45%（2/58），3.45%（2/58），6.90%（4/58） and 3.45%（2/58），respectively；the incidence of fever，hematuria，bloody stool，urinary tract infection，urinary tract infection，urinary irritation symptoms，perineal swelling and urinary retention in transrectal prostate puncture biopsy group was 10.17%（6/59），10.17%（6/59），16.95%（10/59），15.25%（9/59），3.39%（2/59），0.00%（0/59） and 1.69%（1/59），respectively.The incidences of fever，bloody stool and urinary tract infection in transperineal prostate puncture biopsy group were significantly lower than those in transrectal prostate puncture biopsy group（P<0.05），but the incidence of perineal swelling in transperineal prostate puncture biopsy group was significantly higher than that in transrectal prostate puncture biopsy group（P<0.05）.There was no significant difference in the incidences of hematuria，urinary irritation symptoms and urine retention between the two groups（P>0.05）.The total incidence of complications in transperineal prostate puncture biopsy group and transrectal prostate puncture biopsy group was 31.03%（18/58） and 57.63%（34/59） respectively，the total incidence of complications in transperineal prostate puncture biopsy group was significantly lower than that in transrectal prostate puncture biopsy group（P<0.05）.Conclusion　The results of transperineal prostate puncture biopsy and transrectal prostate puncture biopsy are similar，but the incidence of complications associated with the transperineal prostate puncture biopsy is significantly lower.

参考文献/References:

［1］　HODGE K K，MCNEAL J E，TERRIS M K，et al.Random systematic versus directed ultrasound guided transrectal core biopsies of the prostate［J］.J Urol，1989，142（1）：71-74.
［2］　山刚志，虞巍，金杰.6针法和13针法前列腺活检术诊断前列腺癌的分析比较［J］.中国男科学杂志，2006，20（2）：19-21，25.
［3］　王文营，邵强，杜林栋，等.前列腺穿刺活检研究近况［J］.中华泌尿外科杂志，2006，27（2）：141-143.
［4］　YAO M H，ZOU L L，WU R，et al.Transperineal ultrasoundguided 12-core prostate biopsy：an extended approach approach to diagnose transition zone prostate tumors［J］.PLoS One，2014，9（2）：e89171.
［5］　TAKENAKA A，HARA R，ISHIMURA T，et al.A prospective randomizaed comparison of diagnostic efficacy between transperineal and transrectal 12-core prostate biopsy［J］.Prostate Cancer Prostatic Dis，2008，11（2）：134-138.
［6］　张峰波，邵强，尚东浩，等.经会阴径路与经直肠径路前列腺穿刺活检的对比性研究［J］.中华泌尿外科杂志，2009，15（12）：1133-1135.
［7］　IRANI J，BLANCHET P，SALOMON L，et al.Is an extended 20-core prostate biopsy protocol more efficient than the standard 12-core A randomized multicenter trial［J］.J Urol，2013，190（1）：77-83.
［8］　金锡御，吴雄飞.尿道外科学［M］.北京：人民出卫生出版社，2004：189-192.
［9］　吴嘉，马扬之，陈忠，等.6点与12点前列腺穿刺活组织检查诊断前列腺癌的回顾性分析［J］.上海医学，2011，34（7）：532-535.
［10］　YOON B I，SHIN T S，CHO H J，et al.Is it effective to perform two more prostate biopsies according to prostate-specific antigen level and prostate volume in detecing prostate cancer？Prospective study of 10-core and 12-core prostate biopsy［J］.Urol J，2012，9（2）：491-497.

相似文献/References:

[1]张会清,张英杰,窦启峰,等.经尿道电汽化切除术治疗前列腺癌[J].新乡医学院学报,2000,17(06):447.
[2]牛保华,高新平,胡艳牧.p16 蛋白在前列腺癌的表达及其意义[J].新乡医学院学报,2001,18(04):251.
[3]孙继建,陈春晓,李海营.经尿道前列腺电切联合内分泌治疗高龄前列腺癌疗效观察[J].新乡医学院学报,2008,25(05):519.
[4]范毛川,余沁楠,朱　峰,等.腹腔镜前列腺癌根治术与开放性前列腺癌根治术治疗早期前列腺癌疗效比较[J].新乡医学院学报,2019,36(8):748.[doi:10.7683/xxyxyxb.2019.08.011]
　FAN Mao-chuan,YU Qin-nan,ZHU Feng,et al.Comparison of the effect of laparoscopic radical prostatectomy and open radical prostatectomy in the treatment of early prostate cancer[J].Journal of Xinxiang Medical University,2019,36(3):748.[doi:10.7683/xxyxyxb.2019.08.011]
[5]李　金,周柱玉,王锦亮,等.直肠超声引导下经会阴与经直肠前列腺穿刺活检术临床价值比较[J].新乡医学院学报,2020,37(8):747.[doi:10.7683/xxyxyxb.2020.08.010]
　LI Jin,ZHOU Zhuyu,WANG Jinliang,et al.Comparison of clinical value between transperineal and transrectal prostate puncture biopsy guided by rectal ultrasound[J].Journal of Xinxiang Medical University,2020,37(3):747.[doi:10.7683/xxyxyxb.2020.08.010]
[6]李　军.不同年龄前列腺癌患者的临床病理特征与生存状况分析[J].新乡医学院学报,2020,37(9):862.[doi:10.7683/xxyxyxb.2020.09.013]
　LI Jun.Clinicopathological characteristics and survival status of prostate cancer patients at different ages[J].Journal of Xinxiang Medical University,2020,37(3):862.[doi:10.7683/xxyxyxb.2020.09.013]
[7]余沁楠,侯国栋,薛向东,等.腹腔镜下前列腺癌根治术临床疗效观察[J].新乡医学院学报,2018,35(4):317.[doi:10.7683/xxyxyxb.2018.04.015]
　YU Qin-nan,HOU Guo-dong,XUE Xiang-dong,et al.Effect of laparoscopic radical prostatectomy on the patients with prostate cancer[J].Journal of Xinxiang Medical University,2018,35(3):317.[doi:10.7683/xxyxyxb.2018.04.015]
[8]梅将军,江　怡,张　波,等.经直肠弹性成像联合经直肠超声造影在前列腺癌诊断中的价值[J].新乡医学院学报,2018,35(10):895.[doi:10.7683/xxyxyxb.2018.10.011]
　MEI Jiang-jun,JIANG Yi,ZHANG Bo,et al.Diagnostic value of transrectal elastography combined with transrectal contrast-enhanced ultrasound in prostate carcinoma[J].Journal of Xinxiang Medical University,2018,35(3):895.[doi:10.7683/xxyxyxb.2018.10.011]
[9]朱海松.经腹膜外与经腹腔腹腔镜前列腺癌根治术治疗前列腺癌疗效比较[J].新乡医学院学报,2022,39(7):626.[doi:10.7683/xxyxyxb.2022.07.006]
　ZHU Haisong.Comparison of curative effect between extraperitoneal and transabdominal laparoscopic radical prostatectomy for prostate cancer[J].Journal of Xinxiang Medical University,2022,39(3):626.[doi:10.7683/xxyxyxb.2022.07.006]
[10]朱海松,卢学仁.坦索罗辛联合远期外科手术治疗局限性前列腺癌术后排尿困难及尿潴留的临床效果观察[J].新乡医学院学报,2016,33(6):511.[doi:10.7683/xxyxyxb.2016.06.018]
　ZHU Hai-song,LU Xue-ren.Clinical effect of tamsulosin combined with long-term surgical treatment for postoperative dysuria and urinary retention in patients with localized prostate cancer[J].Journal of Xinxiang Medical University,2016,33(3):511.[doi:10.7683/xxyxyxb.2016.06.018]

更新日期/Last Update: 2017-03-05