[1]李 军.不同年龄前列腺癌患者的临床病理特征与生存状况分析[J].新乡医学院学报,2020,37(9):862-864.[doi:10.7683/xxyxyxb.2020.09.013]
 LI Jun.Clinicopathological characteristics and survival status of prostate cancer patients at different ages[J].Journal of Xinxiang Medical University,2020,37(9):862-864.[doi:10.7683/xxyxyxb.2020.09.013]
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不同年龄前列腺癌患者的临床病理特征与生存状况分析
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《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
37
期数:
2020年9
页码:
862-864
栏目:
临床研究
出版日期:
2020-09-05

文章信息/Info

Title:
Clinicopathological characteristics and survival status of prostate cancer patients at different ages
作者:
李 军
(驻马店市中心医院泌尿外科,河南 驻马店 463000)
Author(s):
LI Jun
(Department of Urology,Zhumadian Central Hospital,Zhumadian 463000,Henan Province,China)
关键词:
前列腺癌年龄临床病理特征生存状况
Keywords:
prostate cancerageclinicopathological characteristicssurvival status
分类号:
R737.25
DOI:
10.7683/xxyxyxb.2020.09.013
文献标志码:
A
摘要:
目的 探讨不同年龄段前列腺癌患者的临床病理特征与生存状况。方法 选择2014年1月至2017年12月驻马店市中心医院收治的116例前列腺癌患者为研究对象,根据患者的年龄分为低龄组(≤65岁)和高龄组(>65岁),对2组患者的临床病理特征及5 a生存状况进行比较。结果 与高龄组患者比较,低龄组患者前列腺症状较轻,骨痛、骨转移患者比例及血清游离前列腺特异性抗原水平较高,组织分化程度较低(P<0.05);2组患者排尿困难、夜尿增多、不明原因消瘦、家族史、肿瘤TNM分期、治疗方式比较差异无统计学意义(P>0.05)。低龄组和高龄组患者5 a无进展生存率分别为76.5%(39/51)、87.7%(57/65),低龄组患者5 a无进展生存率低于高龄组(χ2=5.975,P<0.05)。低龄组和高龄组患者5 a总生存率分别为84.31%(43/51)、89.23%(58/65),2组患者5 a总生存率比较差异无统计学意义(χ2=0.752,P>0.05)。结论 低龄前列腺癌患者前列腺症状较轻,组织分化程度较低,更易发生骨转移和骨痛,5 a无进展生存率低,需要进行个性化治疗。
Abstract:
Objective To investigate the clinicopathological characteristics and survival status of prostate cancer patients at different ages.Methods A total of 116 patients with prostate cancer admitted to Zhumadian Central Hospital from January 2014 to December 2017 were selected as the research subjects,and they were divided into the low-age group (≤65 years old) and the high-age group (>65 years old) according to the age,and the clinicopathological characteristics and 5-year survival status of the patients were compared between the two groups.Results Compared with the high-age group,the prostate symptom was lighter,the proportion of patients with bone pain and bone metastasis and the level of serum free prostate specific antigen were higher,and the degree of tissue differentiation was lower in the low-age group (P<0.05).There was no significant difference in dysuria,nocturia increasing,unexplained weight loss,family history,TNM staging and treatment method between the two groups (P>0.05).The 5-year progression free survival rate of patients in the low-age group and the high-age group was 76.5% (39/51) and 87.7% (57/65),respectively.The 5-year progression free survival rate of patients in the low-age group was lower than that in the high-age group (χ2=5.975,P<0.05).The 5-year overall survival rate of patients in the low-age group and the high-age group was 84.31% (43/51) and 89.23% (58/65),respectively.There was no significant difference in the 5-year overall survival rate between the two groups (χ2=0.752,P>0.05).Conclusion The low-age patients with prostate cancer have mild prostate symptoms,low degree of tissue differentiation,more bone metastasis and bone pain.The 5-year progression free survival rate of the low-age patients is low,so the individualized treatment is needed.

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更新日期/Last Update: 2020-09-05