[1]单怡凡,李慧君,吴 辉,等.肠道微生物与慢性阻塞性肺疾病和哮喘相关性研究进展[J].新乡医学院学报,2018,35(10):934-936.[doi:10.7683/xxyxyxb.2018.10.022]
 N/A.N/A[J].Journal of Xinxiang Medical University,2018,35(10):934-936.[doi:10.7683/xxyxyxb.2018.10.022]
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肠道微生物与慢性阻塞性肺疾病和哮喘相关性研究进展
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《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
35
期数:
2018年10
页码:
934-936
栏目:
综述
出版日期:
2018-10-05

文章信息/Info

Title:
N/A
作者:
单怡凡李慧君吴 辉李海斌曾 祥李玉春张贵成吴卫东
(新乡医学院公共卫生学院 河南省空气污染健康效应与干预国际联合实验室,河南 新乡 453003)
Author(s):
N/A
N/A
关键词:
肠道微生物慢性阻塞性肺疾病哮喘
Keywords:
N/A
分类号:
R563
DOI:
10.7683/xxyxyxb.2018.10.022
文献标志码:
A
摘要:
人体微生物菌群在免疫系统及机体内环境稳态发展过程中起着非常重要的作用。近年来相关研究表明,呼吸道和肠道中微生物组成和功能的改变与免疫应答的改变及肺部疾病的发展相关,这为哮喘、慢性阻塞性肺疾病(COPD)等呼吸道疾病的治疗和预防提供了新的思路和方向,本文重点综述了肠道菌群与哮喘和COPD相关性的研究进展。
Abstract:
N/A

参考文献/References:

[1] YAZAR A,ATIS S,KONCA K,et al.Respiratory symptoms and pulmonary functional changes in patients with irritable bowel syndrome[J].Am J Gastroenterol,2001,96(5):1511-1516.
[2] KEELY S,TALLEY N J,HANSBRO P M.Pulmonary-intestinal cross-talk in mucosal inflammatory disease[J].Mucosal Immunol,2012,5(1):7-18.
[3] VIEIRA W A,PRETORIUS E.The impact of asthma on the gastrointestinal tract(GIT)[J].J Asthma Allergy,2010,3:123-130.
[4] DONALDSON G P,LEE S M,MAZMANIAN S K.Gut biogeography of the bacterial microbiota[J].Nat Rev Microbiol,2015,14(1):20-32.
[5] BUFFIE C G,PAMER E G.Microbiota-mediated colonization resistance against intestinal pathogens[J].Nat Rev Immunol,2013,13(11):790-801.
[6] 林璋,祖先鹏,谢海胜,等.肠道菌群与人体疾病发病机制的研究进展[J].药学学报,2016,51(6):843-852.
[7] MORRIS A,BECK J M,SCHLOSS P D,et al.Comparison of the respiratory microbiome in healthy nonsmokers and smokers[J].Am J Respir Crit Care Med,2013,187(10):1067-1075.
[8] BASSIS C M,ERBDOWNWARD J R,DICKSON R P,et al.Analysis of the upper respiratory tract microbiotas as the source of the lung and gastric microbiotas in healthy individuals[J].MBio,2015,6(2):e00037.
[9] 孙夏烨.儿童哮喘与肠道菌群[J].国际儿科学杂志,2014,41(3):233-236.
[10] HEVIA A,MILANI C,LPEZ P,et al.Allergic patients with long-term asthma display low levels of Bifidobacterium adolescentis[J].PLoS One,2016,11(2):e0147809.
[11] HUA X,GOEDERT J J,PU A,et al.Allergy associations with the adult fecal microbiota:analysis of the American gut project[J].Ebiomedicine,2016,3(C):172-179.
[12] HE F,MORITA H,OUWEHAND A C,et al.Stimulation of the secretion of pro-inflammatory cytokines by Bifidobacterium strains[J].Microbiol Immunol,2013,46(11):781-785.
[13] JOHNSON J L,JONES M B,COBB B A.Bacterial capsular polysaccharide prevents the onset of asthma through T-cell activation[J].Glycobiology,2015,25(4):368-375.
[14] SEHRAWAT A,SINHA S,SAXENA A.Helicobacter pylori neutrophil-activating protein:a potential Treg modulator suppressing allergic asthma[J].Front Microbiol,2015,6:493.
[15] KOCH K N,HARTUNG M L,URBAN S,et al.Helicobacter urease-induced activation of the TLR2/NLRP3/IL-18 axis protects against asthma[J].J Clin Invest,2015,125(8):3297-3302.
[16] ENGLER D B,SEBASTIAN R,YOLANDA V W,et al.Effective treatment of allergic airway inflammation with Helicobacter pylori immunomodulators requires BATF3-dependent dendritic cells and IL-10[J].Proc Natl Acad Sci USA,2014,111(32):11810-11815.
[17] BUDDEN K F,GELLATLY S L,WOOD D L A,et al.Emerging pathogenic links between microbiota and the gut-lung axis[J].Nat Rev Microbiol,2016,15(1):55-63.
[18] 史琦,王辛秋,孔艳华,等.浅述慢性阻塞性肺疾病与肠道菌群微生态失衡的关系[J].世界中西医结合杂志,2016,11(5):732-736.
[19] SEGAL L N,ALEKSEYENKO A V,CLEMENTE J C,et al.Enrichment of lung microbiome with supraglottic taxa is associated with increased pulmonary inflammation[J].Microbiome,2013,1(1):19.
[20] PRAGMAN A A,KIM H B,REILLY C S,et al.The lung microbiome in moderate and severe chronic obstructive pulmonary disease[J].PLoS One,2012,7(10):S77-S78.
[21] SZE M A,DIMITRIU P A,HAYASHI S,et al.The lung tissue microbiome in chronic obstructive pulmonary disease[J].Am J Respir Crit Care Med,2012,185(10):1073-1080.
[22] BENJAMIN J L,HEDIN C R,KOUTSOUMPAS A,et al.Smokers with active Crohn′s disease have a clinically relevant dysbiosis of the gastrointestinal microbiota[J].Inflamm Bowel Dis,2012,18(6):1092-1100.
[23] BIEDERMANN L,ZEITZ J,FREI P,et al.Smoking cessation alters intestinal microbiota:insights from quantitative investigations on human fecal samples using FISH[J].Inflamm Bowel Dis,2014,20(9):1496-1501.
[24] SCHWAB C,BERRY D,RAUCH I,et al.Longitudinal study of murine microbiota activity and interactions with the host during acute inflammation and recovery[J].ISME,2014,8(5):1101-1114.
[25] VERSCHUERE S,BRACKE K R,DEMOOR T,et al.Cigarette smoking alters epithelial apoptosis and immune composition in murine GALT[J].Lab Invest,2011,91(7):1056-1067.
[26] ALLAIS L,KERCKHOF F M,VERSCHUERE S,et al.Chronic cigarette smoke exposure induces microbial and inflammatory shifts and mucin changes in the murine gut[J].Environ Microbiol,2016,18(5):1352-1363.
[27] HAMMADI M,ADI M,JOHN R,et al.Dysregulation of gastric H,K-ATPase by cigarette smoke extract[J].World J Gastroenterol,2009,15(32):4016-4022.
[28] SAPKOTA A R,BERGER S,VOGEL T M.Human pathogens abundant in the bacterial metagenome of cigarettes[J].Environ Health Perspect,2010,118(3):351-356.
[29] HU J,WEI T,SUN S,et al.Effects of cigarette smoke condensate on the production and characterization of exopolysaccharides by Bifidobacterium[J].An Acad Bras Cienc,2015,87(2):997-1005.
[30] REALE M,BOSCOLO P,BELLANTE V,et al.Daily intake of Lactobacillus casei Shirota increases natural killer cell activity in smokers[J].Br J Nutr,2012,108(2):308-314.
[31] VERHEIJDEN K A T,GARSSEN J,BEZEMER G F G,et al.Treatment with specific prebiotics or probiotics prevents the development of lung emphysema in a mouse model of COPD[J].Europ J Pharmacol,2011,668:e3-e12.
[32] MORTAZ E,ADCOCK I M,RICCIARDOLO F L,et al.Anti-inflammatory effects of Lactobacillus rahmnosus and Bifidobacterium breve on cigarette smoke activated human macrophages[J].PLoS One,2015,10(8):e0136455.
[33] TOMODA K,KUBO K,DAIRIKI K,et al.Whey peptide-based enteral diet attenuated elastase-induced emphysema with increase in short chain fatty acids in mice[J].BMC Pulm Med,2015,15(1):1-7.
[34] TOMODA K,KUBO K,ASAHARA T,et al.Cigarette smoke decreases organic acids levels and population of Bifidobacterium in the caecum of rats[J].J Toxicol Sci,2011,36(3):261-266.
[35] KISH L,HOTTE N,KAPLAN G G,et al.Environmental particulate matter induces murine intestinal inflammatory responses and alters the gut microbiome[J].PLoS One,2013,8(4):e62220.
[36] KELLY C J,ZHENG L,CAMPBELL E L,et al.Crosstalk between microbiota-derived short-chain fatty acids and intestinal epithelial hif augments tissue barrier function[J].Cell Host Microbe,2015,17(5):662-671.
[37] SUZUKI T,YOSHIDA S,HARA H.Physiological concentrations of short-chain fatty acids immediately suppress colonic epithelial permeability[J].Br J Nutr,2008,100(2):297-305.
[38] 孔艳华,史琦,阎玥,等.理肺汤对慢性阻塞性肺疾病大鼠肠道菌群和炎性因子的影响[J].中华中医药杂志,2017,32(1):341-343.

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更新日期/Last Update: 2018-10-05