[1]职晓松,黄筱奕,訾晓渊,等.长链非编码RNA PVT1在肿瘤中的作用研究进展[J].新乡医学院学报,2016,33(3):243-245.[doi:10.7683/xxyxyxb.2016.03.022]
　ZHI Xiaosong,HUANG Xiaoyi,ZI Xiaoyuan,et al.Research progress on the role of long-chain noncoding RNAPVT1 in tumors[J].Journal of Xinxiang Medical University,2016,33(3):243-245.[doi:10.7683/xxyxyxb.2016.03.022]
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长链非编码RNA PVT1在肿瘤中的作用研究进展
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《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
33
期数:
2016年3
页码:
243-245
栏目:
综述
出版日期:
2016-03-05

文章信息/Info

Title:
Research progress on the role of long-chain noncoding RNAPVT1 in tumors
作者:
职晓松1; 黄筱奕2; 訾晓渊1; 胡以平1
（1.第二军医大学基础部细胞生物教研室，上海　200433；2.第二军医大学附属长海医院病理科，上海　200433）
Author(s):
ZHI Xiaosong; HUANG Xiaoyi; ZI Xiaoyuan; HU Yiping
关键词:
长链非编码RNA; PVT1; 肿瘤; 基因位点; 表达上调
分类号:
R73
DOI:
10.7683/xxyxyxb.2016.03.022
文献标志码:
A
摘要:
长链非编码RNA（lncRNA）是长度超过200个核苷酸的不具有编码蛋白质功能的RNA，在调控细胞增殖和分化中发挥重要作用。研究发现，lncRNA PVT1在多个恶性肿瘤中表达上调，而且其基因位点与癌基因myc相邻。虽然PVT1参与肿瘤发生发展的具体分子机制仍不清楚，但PVT1因其基因位点特殊性和表达的时空特异性而受到了广泛关注。

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更新日期/Last Update: 2016-03-05