[1]赵雪薇,陈珮琪,牛延翔,等.帕金森病的病因及发病机制研究进展[J].新乡医学院学报,2021,38(4):378-381.[doi:10.7683/xxyxyxb.2021.04.018]
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帕金森病的病因及发病机制研究进展
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《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
38
期数:
2021年4
页码:
378-381
栏目:
综述
出版日期:
2021-04-05

文章信息/Info

作者:
赵雪薇123陈珮琪123牛延翔123张凌星123高智贤123王 昌123赵宗亚123于 毅123
(1.新乡医学院医学工程学院,河南 新乡 4530032.新乡医学院神经传感与控制实验室,河南 新乡 4530033.新乡市神经传感与控制工程技术研究中心,河南 新乡 453003)
关键词:
帕金森病发病机制研究进展
分类号:
R742.5
DOI:
10.7683/xxyxyxb.2021.04.018
文献标志码:
A
摘要:
帕金森病(PD)是因中脑黑质多巴胺能神经元进行性缺失所造成的一种神经系统疾病,多发生于中老年人,临床上多伴随一系列运动及非运动症状,病程长且无法彻底治愈,严重影响到患者的生活质量,随着人口老龄化,其发病率呈逐年增高的趋势,给家庭和社会都造成了很大的负担。因此,探讨PD的发病机制和有效的治疗方法成为近年来学术界研究的热点,明确其病因及发病机制有助于从源头上给予积极防治,有效降低PD的发病率,提高患者的生存率。但PD发病机制复杂,研究相对困难,目前其病因及发病机制尚未完全明确。本文从氧化应激反应、神经毒性作用、炎症反应及免疫反应等方面对该病的发病机制作一综述。

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更新日期/Last Update: 2021-04-05