[1]耿红芳,王 旭.肺保护性通气模式对高龄脊柱融合术患者肺功能的影响及机制[J].新乡医学院学报,2017,34(8):693-696.[doi:10.7683/xxyxyxb.2017.08.008]
 GENG Hong-fang,WANG Xu.Effect of lung protective ventilation mode on the lung function of elderly patients with spinal fusion and its mechanism[J].Journal of Xinxiang Medical University,2017,34(8):693-696.[doi:10.7683/xxyxyxb.2017.08.008]
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肺保护性通气模式对高龄脊柱融合术患者肺功能的影响及机制
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《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
34
期数:
2017年8
页码:
693-696
栏目:
临床研究
出版日期:
2017-08-05

文章信息/Info

Title:
Effect of lung protective ventilation mode on the lung function of elderly patients with spinal fusion and its mechanism
作者:
耿红芳王 旭
(河南省人民医院麻醉科,河南 郑州 450003)
Author(s):
GENG Hong-fangWANG Xu
(Department of Anesthesiology,Henan Provincial People′s Hospital,Zhengzhou 450003,Henan Province,China)
关键词:
全身麻醉肺保护性通气脊柱融合术肺功能
Keywords:
general anesthesialung protective ventilationspinal fusionlung function
分类号:
R687.3
DOI:
10.7683/xxyxyxb.2017.08.008
文献标志码:
A
摘要:
目的 探讨肺保护性通气(PMV)模式对高龄脊柱融合术患者肺功能的影响及其机制。方法 选择2014年1月至2015年12月在河南省人民医院接受脊柱融合术的68例高龄患者作为研究对象,将患者分为观察组和对照组,每组34例。对照组患者采用常规机械通气 (CMV)模式,观察组患者采用PMV模式。对2组患者的手术情况、肺功能指标及并发症进行比较。结果 对照组患者手术时间、拔管时间、通气时间及术中出血量分别为(159.2±28.6)、(47.8±14.2)、(197.4±63.0)min和(575.8±129.4)mL,观察组患者上述各指标分别为(140.3±29.4)、(21.2±7.3)、(182.6±59.5)min 和(559.1±114.7)mL;2组患者的手术时间、通气时间及出血量比较差异均无统计学意义(P>0.05),观察组患者拔管时间显著短于对照组(P<0.05)。对照组患者的氧合指数(OI)、呼吸指数(RI)、动态顺应性(Cd)及静态顺应性(Cs)分别为 207.17±0.12、1.02±0.03、36.68±1.04、108.36±0.93,观察组患者的OI、RI、Cd及Cs分别为264.19±0.14、1.89±0.02、48.34±0.95、146.27±0.86;观察组患者的OI、RI、Cd及Cs均高于对照组 (P<0.05)。对照组患者呼吸机相关性肺炎(VAP)、呼吸道并发症、呼吸衰竭、低氧血症及肺水肿的发生率分别为17.65%(6/34)、32.35%(11/34)、20.59%(7/34)、17.65%(6/34)、11.76%(4/34),观察组患者VAP、呼吸道并发症、呼吸衰竭、低氧血症及肺水肿发生率分别为0.00%(0/34)、11.76%(4/34)、2.94%(1/34)、5.88%(2/34)、0.00%(0/34);观察组患者VAP、呼吸道并发症、呼吸衰竭、低氧血症及肺水肿等并发症的发生率均显著低于对照组(P<0.05)。结论 高龄脊柱融合术患者采用PMV可降低手术对患者肺功能的影响及并发症发生率。
Abstract:
Objective To explore the effect of lung protective ventilation mode on the lung function of elderly patients with spinal fusion and its mechanism.Methods A total of 68 patients who underwent the spinal fusion in Henan Provincial People′s Hospital from January 2014 to December 2015 were selected as the study objects.The patients were divided into observation group and control group,with 34 patients in each group.The patients in control group were given conventional mechanical ventilation (CMV);the patients in observation group were given lung protective ventilation (PMV).The surgery indicators,indexes of lung function and complications of patients were compared between the two groups.Results The operation time,extubation time,ventilation time and intraoperative blood loss in control group was (159.2±28.6),(47.8±14.2),(197.4±63.0)min and (575.8±129.4)mL respectively;and the above index in observation group was(140.3±29.4),(21.2±7.3),(182.6±59.5)min and (559.1±114.7)mL respectively.There was no significant difference in the operation time,ventilation time and blood loss between the two groups(P>0.05),the extubation time after surgery in the observation group was significantly shorter than that in the control group(P<0.05).The oxygenation index(OI),respiratory index(RI),dynamic compliance(Cd) and static compliance(Cs) of patients in the control group was 207.17±0.12,1.02±0.03,36.68±1.04 and 108.36±0.93 respectively;and the OI,RI,Cd,Cs of patients in the observation group was 264.19±0.14,1.89±0.02,48.34±0.95,146.27±0.86 respectively.The OI,RI,Cd and Cs of patients in the observation group were significantly higher than those in the control group(P<0.05).The incidence of the associated pneumonia of ventilator (VAP),the upper airway complications,respiratory failure,hypoxemia and pulmonary edema of patients in control group was 17.65%(6/34),32.35%(11/34),20.59%(7/34),17.65%(6/34) and 11.76%(4/34) respectively;and the above index in observation group was 0.00%(0/34),11.76%(4/34),2.94%(1/34),5.88%(2/34) and 0.00%(0/34) respectively.The incidence of VAP,the upper airway complications,respiratory failure,hypoxemia and pulmonary edema of patients in observation group were significantly lower than those in the control group (P<0.05).Conclusion In elderly patients who undergo spinal fusion,the PMV can reduce the impact of surgery on lung function and reduce the incidence of complications.

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更新日期/Last Update: 2017-08-05