[1]周艳君,王 鹏,李树军,等.豫北地区2014~2016年9项呼吸道病原体的临床分布和流行病学特征[J].新乡医学院学报,2017,34(11):982-986.[doi:10.7683/xxyxyxb.2017.11.007]
 ZHOU Yan-jun,WANG Peng,LI Shu-jun,et al.Clinical distribution and epidemiological feature of nine respiratory pathogens in the northern area of Henan Province from 2014 to 2016[J].Journal of Xinxiang Medical University,2017,34(11):982-986.[doi:10.7683/xxyxyxb.2017.11.007]
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豫北地区2014~2016年9项呼吸道病原体的临床分布和流行病学特征
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《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
34
期数:
2017年11
页码:
982-986
栏目:
临床研究
出版日期:
2017-11-05

文章信息/Info

Title:
Clinical distribution and epidemiological feature of nine respiratory pathogens in the northern area of Henan Province from 2014 to 2016
作者:
周艳君1王 鹏2李树军3王向鹏4
(1.新乡医学院第一附属医院检验科,河南 卫辉 453100;2.新乡医学院第三附属医院输血科,河南 新乡 453003;3.新乡医学院第一附属医院儿科重症监护治疗病房,河南 卫辉 453100;4.新乡医学院检验学院,河南 新乡 453003)
Author(s):
ZHOU Yan-jun1WANG Peng2LI Shu-jun3WANG Xiang-peng4
(1.Department of Clinical Laboratory,the First Affiliated Hospital of Xinxiang Medical University,Weihui 453100,Henan Province,China;2.Department of Blood Transfusion,the Third Affiliated Hospital of Xinxiang Medical University,Xinxiang 453003,Henan Province,China;3.Pediatric Intensive Care Unit,the First Affiliated Hospital of Xinxiang Medical University,Weihui 453100,Henan Province,China;4.Medical Laboratory College of Xinxiang Medical University,Xinxiang 453003,Henan Province,China)
关键词:
豫北地区9项呼吸道病原体临床分布流行病学特征
Keywords:
northern Henan Provincenine respiratory tract pathogensclinical distributionepidemiological feature
分类号:
R378.4+1
DOI:
10.7683/xxyxyxb.2017.11.007
文献标志码:
A
摘要:
目的 了解豫北地区急性呼吸道感染患者9项呼吸道病原体的临床分布和流行病学特征,为临床有效防治急性呼吸道感染性疾病提供病原学参考依据。方法 回顾性分析2014年12月至2016年11月临床送检的11 135例血清标本,采用间接免疫荧光法检测呼吸道病原体,分析9项呼吸道病原体的临床分布和流行病学特征。结果 9项呼吸道病原体感染病例数为2 630例,感染率为23.62%;位居前4位的呼吸道病原体分别为肺炎支原体(16.63%)、乙型流感病毒(2.41%)、副流感病毒(2.29%)、腺病毒(0.79%);男、女性患者9项呼吸道病原体感染率分别为21.60%(1 516/7 020)、27.07%(1 114/4 115)。<1岁组、1~5岁组、6~14岁组、15~30岁组、31~50岁组、>50岁组患者9项呼吸道病原体感染率分别为8.91%(330/3 702)、31.12%(1 424/4 576)、37.36%(634/1 697)、27.10%(90/332)、24.64%(69/280)、15.13%(83/548);<1岁组患者9项呼吸道病原体感染率低于其余5组(P<0.05)。春季组、夏季组、秋季组、冬季组患者9项呼吸道病原体感染率分别为24.66%(591/2 396)、23.86%(631/2 645)、31.09%(748/2 406)、17.90%(660/3 688),秋季组患者9项呼吸道病原体感染率高于其他3组(P<0.05)。2 630例感染患者中,混合感染患者253例,均为二重混合感染,混合感染率为2.27%。结论 不同性别、不同年龄、不同季节呼吸道病原体的感染率是不同的;病毒是急性呼吸道感染的主要病原体;感染存在多重性,病原体呈现季节性分布,春秋季节更应加强预防感染的流行。
Abstract:
Objective To investigate the clinical distribution and epidemiological feature of nine respiratory pathogens of acute respiratory tract infection patients in the northern area of Henan Province,in order to provide reference for clinical effective prevention and treatment of acute respiratory tract infection.Methods The clinical distribution and epidemiological feature of nine respiratory pathogens were analyzed by a retrospective review of 11 135 serum samples which were detected by indirect immunofluorescence method from December 2014 to November 2016.Results There were 2 630 cases with nine respiratory pathogens infection,the infection rate was 23.62%.The main four respiratory pathogens were mycoplasma pneumonia(16.63%),influenza B virus(2.41%),parainfluenza virus(2.29%),adenovirus(0.79%).The nine respiratory pathogens infection rate of male and female was 21.60%(1 516/7 020) and 27.07%(1 114/4 115),respectively.The nine respiratory pathogens infection rate of <1 year group,1-5 years group,6-14 years group,15-30 years group,31-50 years group and >50 years group was 8.91%(330/3 702),31.12%(1 424/4 576),37.36%(634/1 697),27.10%(90/332),24.64%(69/280),15.13%(83/548),respectively.The nine respiratory pathogens infection rate of <1 year group was lower than that of the other five groups(P<0.05).The nine respiratory pathogens infection rate of spring group,summer group,autumn group and winter group was 24.66%(591/2 396)、23.86%(631/2 645)、31.09%(748/2 406)、17.90%(660/3 688),respectively.The nine respiratory pathogens infection rate of autumn group was higher than that of the other three groups(P<0.05).There were 253 patients with polyinfection which all were amphimorphic polyinfection in the 2 630 patients with respiratory pathogens infection,the polyinfection rate was 2.27%.Conclusion Respiratory pathogen infection rate was different because of different gender,different age and different season.The virus was the main pathogen of acute respiratory tract infection.Because of multiplicity of infection and seasonal distribution of pathogens,the prevention of the epidemic should be strengthened in spring and autumn season especially.

参考文献/References:

[1] MERMOND S E.Lower respiratory infections among hospitalized children in New Caledonia:a pilot study for the Pneumonia Etiology Researchfor Child Health project[J].Clin Infect Dis,2012,52(S2):180-189.
[2] 葛均波,徐永健.内科学[M].8版.北京:人民卫生出版社,2013:5-20.
[3] 芝敏,贺捷,张斌,等.乌鲁木齐地区冬春季小儿呼吸道感染者中呼吸道合胞病毒感染的研究[J].中华微生物学和免疫学杂志,2011,31(4):316-319.
[4] 秦茵茵,吴国锋,秦笙,等.九项呼吸道联检试剂对多种呼吸道感染病原体检测的临床意义[J].中华生物医学工程杂志,2012,18(2):124-127.
[5] 薛白,刘洁,胡志刚,等.呼吸道感染患者病原学调查分析[J].中华医院感染学杂志,2014,24(2):309-311.
[6] 汤美玲,刘洪根,胡丽娟.深圳市儿童急性呼吸道感染的病原学流行特点[J].临床儿科杂志,2016,34(10):796-797.
[7] 王梅.小儿急性呼吸道感染的病原学研究[J].中国儿童保健杂志,2003,11(2):117-118.
[8] 王加芬,王凤秀,郑媛媛,等.呼吸道病毒特异性IgM 检测对儿童呼吸道感染的指导意义[J].中国免疫学杂志,2015,31(2):257-260.
[9] 王宇清,季伟,陈正荣,等.急性呼吸道感染8 172例住院患儿病原学分析[J].中国实用儿科杂志,2012,27(11):834-839.
[10] JOHNSTONE J,MAJUMDAR S R,FOX J D,et al.Viral infection in adults hospitalized with community-acquired pneumonia:prevalence,pathogens,and resentation[J].Chest,2008,134(6):1141-1148.
[11] 王洪建.呼吸道九联检试剂在儿童呼吸道感染病原体检测中的临床意义探讨[J].河南医学研究,2015,24(11):19-20.
[12] 刘建华,路素坤,帅金凤,等.分泌物堵塞呼吸道的儿童肺炎支原体肺炎临床特征[J].中华实用儿科临床杂志,2015,30(24):1888-1890.
[13] 李美香,李荣香,曲政海,等.社区获得性肺炎支原体肺炎儿童血清抗体滴度的变化[J].中华实用儿科临床杂志,2016,31(21):1642-1645.
[14] 谢红梅,胡必杰,马艳,等.1 647例呼吸道感染病原体的IgM抗体检测结果分析[J].中华医院感染学杂志,2012,22(12):2696-2698.
[15] 何秀娟,李全亭,王红,等.2 730例呼吸道病原体谱抗体IgM 检测结果分析[J].中国卫生检验杂志,2016,26(15):2246-2248.
[16] 李艳霞,孟保福,宋红琳,等.九项联检试剂对多种呼吸道感染病原体检测的临床价值[J].中国卫生检验杂志,2014,24(8):1118-1119.
[17] 薛白,刘洁,胡志刚,等.呼吸道感染患者病原学调查分析[J].中华医院感染学杂志,2014,24(2):309-311.
[18] 郑辉,彭亮,卓广超.儿童呼吸道感染病原体IgM抗体抗体检测结果分析[J].中华医院感染学杂志,2015,25(1):235-237.
[19] 罗丹,张晓阳,高向阳,等.普洱市儿童呼吸道感染病原体IgM抗体九联检临床应用分析[J].国际检验医学杂志,2016,37(9):1205-1209.
[20] 史晓红,冀涛,王芳芳,等.肺部感染患者军团菌属感染的调查[J].中华医院感染学杂志,2011,21(4):679-681.
[21] CHOROSZY-KROL I,FREJ-MADRZAK M,SAROWSKA J,et al.Detection of chlamydophila pneumoniae antigens in children in the lower silesia region in 2011[J].Adv Clin Exp Med,2014,23(3):411-414.
[22] AMIN A N,CERCEO E A,DEITELZWEIG S B,et al.The hospitalist perspective on treatment of community-acquired bacterial pneumonia[J].Postgrad Med,2014,126(2):18-29.
[23] SOBIESZCZANSKA B M,KASPRZYKOWSKA U,DUDA-MADEJ A,et al.Relevance of serology for Mycoplasma pneumoniae infection among children with persistent cough[J].Adv Clin Exp Med,2014,23(2):185-190.
[24] 史大伟,冯雪莉,王良玉,等.同一家庭中耐药肺炎支原体感染临床分析[J].中华实用儿科临床杂志,2016,31(21):1663-1664.
[25] 韩金芬,王文秀,王川云,等.布地奈德联合阿奇霉素治疗儿童肺炎支原体肺炎疗效观察[J].新乡医学院学报,2016,33(8):684-685,691.
[26] 荀春华,张贤敏,高志亮,等.九江地区1 672例呼吸道感染患者呼吸道病原体的IgM 的检测和分析[J].细胞与分子免疫学杂志,2015,31(3):391-393.

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更新日期/Last Update: 2017-11-05