[1]张海涛,张 娜,杜纪英,等.豫北地区肺炎链球菌感染分布和耐药性分析[J].新乡医学院学报,2016,33(8):668-669.[doi:10.7683/xxyxyxb.2016.08.005]
 ZHANG Hai-tao,ZHANG Na,DU Ji-ying,et al.Distribution and drug resistance analysis of streptococcus pneumoniae infection in North Henan Province[J].Journal of Xinxiang Medical University,2016,33(8):668-669.[doi:10.7683/xxyxyxb.2016.08.005]
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豫北地区肺炎链球菌感染分布和耐药性分析
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《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
33
期数:
2016年8
页码:
668-669
栏目:
临床研究
出版日期:
2016-07-27

文章信息/Info

Title:
Distribution and drug resistance analysis of streptococcus pneumoniae infection in North Henan Province
作者:
张海涛1张 娜2杜纪英1胡东洋1娄婷叶2王明永3
(1.新乡医学院三全学院检验与影像学院,河南 新乡 453000;2.新乡医学院第一附属医院检验科,河南 卫辉 453100;3.新乡医学院医学检验学院,河南 新乡 453003)
Author(s):
ZHANG Hai-tao1ZHANG Na2DU Ji-ying1HU Dong-yang1LOU Ting-ye2WANG Ming-yong3
(1.Inspection and Image Department of Sanquan College,Xinxiang Medical University,Xinxiang 453000,Henan Province,China;2.Department of Laboratory Medicine,the First Affiliated Hospital of Xinxiang Medical University,Xinxiang 453100,Henan Province,China;3.School of Medical Inspection,Xinxiang Medical University,Xinxiang 453003,Henan Province,China)
关键词:
肺炎链球菌多重耐药性医院感染豫北地区
Keywords:
streptococcus pneumoniaemultiple drug resistancehospital inflectionNorth Henan Province
分类号:
R378.1
DOI:
10.7683/xxyxyxb.2016.08.005
文献标志码:
A
摘要:
目的 了解肺炎链球菌(SP)的临床分布及其耐药情况,指导临床医师合理使用抗生素,以延缓多重耐药菌株的产生并有效预防医院获得性感染。方法 收集2015年1~12月新乡医学院第一附属医院检验科分离出的641株SP,采用纸片扩散法进行鉴定及药物敏感试验。分析SP感染患者的年龄分布、标本来源、科室分布及药物敏感试验结果。结果 SP感染者年龄多分布在9岁以下,标本类型主要是痰液(587份,91.6%)。SP对14种抗生素的药物敏感试验结果显示,SP对氯霉素(0.8%)、万古霉素(0.8%)、左旋氧氟沙星(0.6%)及利奈唑胺(0.0%)的耐药率较低;而对克林霉素(99.8%)、复方磺胺甲NFDF9唑(98.3%)、红霉素(99.8%)、四环素(99.5%)的耐药率较高。结论 SP感染者多为儿童,且对抗菌药物存在多重耐药性,临床医生应加强其耐药性检测,合理选择抗菌药物,以减少多重耐药菌株的出现。
Abstract:
Objective To explore the clinical distribution and drug resistance of streptococcus pneumoniae(SP),in order to direct doctors to put antibiotics into intelligent use,delay the occurrence of bacterial drug resistance,and effectively prevent the acquired infection.Methods A total of 641 SP were collected in Department of Laboratory Medicine of the First Affiliated Hospital of Xinxiang Medical University from January to December 2015.The bacteria was separately cultivated and the bacterial identification and drug-sensitivity test were made through Kirby-bauer method.The age distribution,specimen source,division distribution and the result of drug sensitive detection were analyzed.Results The infected cases were mainly under nine years old.The samples were basically isolated from sputum(587,91.6%).The drug sensitivity test result of SP for 14 kinds of antibiotics showed that chloromycetin(0.8%),vancomycin(0.8%),levofloxacin(0.6%) and linezolid(0.0%) had low drug resistance.However,clindamycin(99.8%),bctrim(98.3%),erythromycin(99.8%) and achromycin(99.5%) all had a high drug resistance to SP.Conclusion People inflected SP were mainly children and have multiple drug resistance against antibacterial drug,therefore doctors should strengthen the testing of drug resistance and choose antibacterial drug reasonably so as to lower the occurrence of multiple drug resistance strains.

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更新日期/Last Update: 2016-08-05