[1]赵　迪,张保朝,殷　洁.大脑前循环短暂性脑缺血发作患者大脑中动脉粥样硬化性狭窄高分辨率磁共振形态学分析[J].新乡医学院学报,2017,34(3):209-211.[doi:10.7683/xxyxyxb.2017.03.014]
　ZHAO Di,ZHANG Bao-chao,YIN Jie.High resolution magnetic resonance morphological analysis of middle cerebral artery atherosclerotic stenosis in patients with transient cerebral ischemic attack[J].Journal of Xinxiang Medical University,2017,34(3):209-211.[doi:10.7683/xxyxyxb.2017.03.014]
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大脑前循环短暂性脑缺血发作患者大脑中动脉粥样硬化性狭窄高分辨率磁共振形态学分析
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《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
34
期数:
2017年3
页码:
209-211
栏目:
临床研究
出版日期:
2017-03-05

文章信息/Info

Title:
High resolution magnetic resonance morphological analysis of middle cerebral artery atherosclerotic stenosis in patients with transient cerebral ischemic attack
作者:
赵　迪1; 张保朝2; 殷　洁3
（1.新乡医学院，河南　新乡　453003；2.南阳市中心医院神经内科，河南　南阳　473000；3.南阳市中心医院核磁共振室，河南　南阳　473000）
Author(s):
ZHAO Di1; ZHANG Bao-chao2; YIN Jie2
（1.Xinxiang Medical University，Xinxiang 453003，Henan Province，China；2.Department of Neurology，Nanyang Central Hospital，Nanyang 473000，Henan Province，China；3.Department of Magnetic Resonance，Nanyang Central Hospital，Nanyang 473000，Henan Province，China）
关键词:
高分辨率磁共振; 大脑前循环; 短暂性脑缺血发作; 大脑中动脉; 血管重构
Keywords:
high resolution magnetic resonance imaging; anterior circulation; transient ischemic attack; middle cerebral artery; vascular remodeling
分类号:
R743.3
DOI:
10.7683/xxyxyxb.2017.03.014
文献标志码:
A
摘要:
目的　通过高分辨率磁共振（HRMRI）技术探究前循环短暂性脑缺血发作（TIA）患者大脑中动脉（MCA）粥样硬化性狭窄最狭窄处的管腔狭窄程度、血管壁面积及管壁重构模式与前循环TIA发生的关系。方法　收集2015年1月至2016年1月南阳市中心医院收治的前循环TIA患者93例，均经磁共振血管造影、CT血管造影或数字减影血管造影证实存在MCA粥样硬化性狭窄，根据24 h内TIA发生次数分为频发组（24 h内TIA≥2次）和非频发组（24 h 内TIA<2次）。所有患者入院后1周内行HRMRI检查，对比2组患者MCA最狭窄处的管腔狭窄程度、血管壁面积及管壁重构模式。结果　2组患者MCA最狭窄处管腔面积、参考处管腔面积以及血管狭窄程度比较差异均无统计学意义（P>0.05）。2组患者MCA参考处血管壁面积比较差异无统计学意义（P>0.05）；频发组患者MCA最狭窄处血管壁面积和血管重构率显著大于非频发组（P<0.001）。结论　MCA血管壁的正性重构生长模式是前循环TIA发生的决定性因素。
Abstract:
Objective　To investigate the relationship between the degree of vascular stenosis，stenotic vessel wall area，the remodeling pattern of the vessel wall in the atherosclerotic stenosis site of the middle cerebral artery（MCA） and the occurrence of anterior circulation transient ischemic attack（TIA） by high resolution magnetic resonance imaging（HRMRI）.Methods　Ninety-three patients with TIA were selected from January 2015 to January 2016 in Nanyang Central Hospital，and the middle cerebral artery atherosclerotic stenosis was confirmed by magnetic resonance angiography，CT angiography and digital subtraction angiography.The patients were divided into frequent attack group （TIA≥2 times within 24 h） and non-frequent attack group （TIA <2 times within 24 h） according to the occurrence frequency of TIA within 24 h.All patients underwent HRMRI examination within one week after admission.The degree of stenosis，vessel wall area and reconstruction of MCA were compared between the two groups.Results　There was no significant difference in the area of stenotic vessel，the area of referenced vessel and the degree of stenosis of MCA between the two groups（P> 0.05）.There was no significant difference in the vessel wall area of referenced vessel of MCA between the two groups（P>0.05）.The vessel wall area and the rate of vascular remodeling in the narrowest part of MCA in the frequent attack group were significantly higher than that in the non-frequent attack group（P<0.001）.Conclusion　The positive reconstruction of MCA vessel wall is the decisive factor for the occurrence of anterior circulation TIA.

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更新日期/Last Update: 2017-03-05