[1]翁璐昕.彩色多普勒超声半定量评分对早期慢性乙型病毒性肝炎肝硬化的诊断价值[J].新乡医学院学报,2023,40(11):1061-1064.[doi:10.7683/xxyxyxb.2023.11.010]
　WENG Luxin.Diagnostic value of color Doppler ultrasonography semi-quantitative score for early liver cirrhosis of chronic hepatitis B[J].Journal of Xinxiang Medical University,2023,40(11):1061-1064.[doi:10.7683/xxyxyxb.2023.11.010]
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彩色多普勒超声半定量评分对早期慢性乙型病毒性肝炎肝硬化的诊断价值
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《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
40卷
期数:
2023年11
页码:
1061-1064
栏目:
临床研究
出版日期:
2023-11-05

文章信息/Info

Title:
Diagnostic value of color Doppler ultrasonography semi-quantitative score for early liver cirrhosis of chronic hepatitis B
作者:
翁璐昕
（安阳市肿瘤医院/河南科技大学附属安阳市肿瘤医院超声科，河南　安阳　455000）
Author(s):
WENG Luxin
(Department of Ultrasound,Anyang Cancer Hospital,Anyang Cancer Hospital Affiliated to Henan University of Science and Technology,Anyang 455000,Henan Province,China)
关键词:
慢性乙型病毒性肝炎; 早期肝硬化; 彩色多普勒超声; 半定量评分; 诊断价值
Keywords:
chronic hepatitis B; early liver cirrhosis; color Doppler ultrasonography; semi-quantitative score; diagnostic value
分类号:
R575.1
DOI:
10.7683/xxyxyxb.2023.11.010
文献标志码:
A
摘要:
目的　探讨彩色多普勒超声半定量评分对早期慢性乙型病毒性肝炎（CHB）肝硬化的诊断价值。
方法　选择2019年6月至2022年5月安阳市肿瘤医院收治的98例CHB患者为研究对象，根据肝组织活检结果将患者分为非肝硬化组（n=56）和早期肝硬化组（n=42）。使用彩色多普勒超声仪检查患者肝脏，对肝脏实质回声、表面被膜、边缘形态、肝静脉清晰度、肝内韧带、脾脏面积及胆囊壁参数进行半定量评分，并记录2组患者门静脉形态（门静脉内径）及血流频谱（血流量及血流速）。以肝组织活检结果为“金标准”，评估彩色多普勒超声半定量评分对早期CHB肝硬化的诊断效能。
结果　早期肝硬化组患者超声半定量评分中的肝脏实质回声、表面被膜、边缘形态、肝静脉清晰度、肝内韧带、脾脏面积、胆囊壁评分及总评分均显著高于非肝硬化组（P<0.05）。早期肝硬化组患者的门静脉内径显著大于非肝硬化组，血流量及血流速均显著高于非肝硬化组（P<0.05）。彩色多普勒超声半定量评分诊断CHB早期肝硬化的灵敏度为92.86%，特异度为98.21%，阳性预测值为97.50%，阴性预测值为94.83%，准确度为95.92%。
结论　彩色多普勒超声半定量评分对早期CHB肝硬化的诊断效能较高，此外，可结合患者门静脉形态及血流频谱综合诊断。
Abstract:
Objective　To investigate the diagnostic value of color Doppler ultrasonography semi-quantitative score for early stage liver cirrhosis of chronic hepatitis B (CHB).
Methods　A total of 98 patients with CHB diagnosed in Anyang Cancer Hospital from June 2019 to May 2022 were selected as the study subjects,the patients were divided into the non-cirrhosis group (n=56) and early cirrhosis group (n=42) according to the results of liver tissue biopsy.The patient′s liver was examined by Color Doppler ultrasonography,and the liver parenchyma echo,surface capsule,edge morphology,hepatic vein clarity,intrahepatic ligament,spleen area and gallbladder wall parameters were scored by semi-quantitative scoring,and the portal vein morphology(portal vein diameter) and blood flow spectrum(blood flow and flow velocity) of patients in the two groups were recorded.Taking liver tissue biopsy results as the "gold standard",the diagnostic efficacy of color Doppler ultrasound semi-quantitative score for early liver cirrhosis of CHB was evaluated.
Results　The scores of liver parenchyma echo,surface capsule,edge morphology,hepatic vein clarity,intrahepatic ligament,spleen area and gallbladder wall and total score of color Doppler ultrasound semi-quantitative score of patients in the early cirrhosis group were significantly higher than those in the non-cirrhosis group (P<0.05).The portal vein diameter of patients in the early cirrhosis group was significantly larger than that in the non-cirrhosis group,blood flow rate and blood flow velocity of patients in the early cirrhosis group were significantly higher than those in the non-cirrhosis group(P<0.05).The diagnostic sensitivity of color Doppler ultrasound semi-quantitative score for early liver cirrhosis in CHB was 92.86%,the specificity was 98.21%,the positive predictive value was 97.50%,the negative predictive value was 94.83% and the accuracy was 95.92%.
Conclusion　The color Doppler ultrasound semi-quantitative scoring has a high diagnostic efficiency for early liver cirrhosis of CHB;in addition,the morphology of portal vein and blood flow spectrum of the patients could be combined for comprehensive diagnosis.

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更新日期/Last Update: 2023-11-05