[1]赵桂华,张 娜,徐金义,等.河南省郑州地区居民气道高反应性发病情况调查与分析[J].新乡医学院学报,2022,39(4):346-349.[doi:10.7683/xxyxyxb.2022.04.009]
 ZHAO Guihua,ZHANG Na,XU Jinyi,et al.Investigation and analysis on the incidence of airway hyperresponsiveness among rural residents in Zhengzhou city of Henan province[J].Journal of Xinxiang Medical University,2022,39(4):346-349.[doi:10.7683/xxyxyxb.2022.04.009]
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河南省郑州地区居民气道高反应性发病情况调查与分析
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《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
39
期数:
2022年4
页码:
346-349
栏目:
临床研究
出版日期:
2022-04-05

文章信息/Info

Title:
Investigation and analysis on the incidence of airway hyperresponsiveness among rural residents in Zhengzhou city of Henan province
作者:
赵桂华1张 娜1徐金义1张 静1王云朋1王晓娜1郭现平1赵丽敏2
(1.河南省人民医院心肺功能科,河南 郑州 450003;2.河南省人民医院呼吸科,河南 郑州 450003)
Author(s):
ZHAO Guihua1ZHANG Na1XU Jinyi1ZHANG Jing1WANG Yunpeng1WANG Xiaona1GUO Xianping1ZHAO Limin2
(1.Department of Cardiology function,Henan Provincial People′s Hospital,Zhengzhou 450003,Henan Province,China;2.Department of respiratory and critical care medicine,Henan Provincial People′s Hospital,Zhengzhou 450003,Henan Province,China)
关键词:
肺通气功能支气管激发试验气道高反应
Keywords:
lung ventilation functionbronchial provocation testairway hyperresponsiveness
分类号:
R56
DOI:
10.7683/xxyxyxb.2022.04.009
文献标志码:
A
摘要:
目的 调查分析河南省气道高反应性(AHR)发病情况。方法 选择2016年1月至2019年12月于郑州大学附属人民医院(河南省人民医院)就诊和体检的31 602人为受试者。采用肺功能仪检测所有受试者的肺通气功能,并根据肺通气功能不同将受试者分为正常组(肺通气功能正常)、小气道功能减低组(小气道功能减低)、轻度阻塞性组(轻度阻塞性肺通气功能障碍)、轻度限制性组(轻度限制性肺通气功能障碍)。采用支气管激发试验检测所有受试者AHR情况。结果 31 602例受试者中,AHR总检出率为29.48%(9 318/31 602),男性AHR检出率为28.42%(4 173/14 685),女性AHR检出率为30.41%(5 145/16 917),男性与女性AHR检出率比较差异无统计学意义(χ2=1.618,P>0.05)。21~29岁、30~39岁,40~49岁、50~59岁女性的AHR检出率均显著高于男性相应年龄范围(P<0.05);6~20岁、60~69岁、≥70岁男性与女性的AHR检出率比较差异无统计学意义(P>0.05);6~20岁男性、女性就诊人群的AHR检出率均显著高于其他年龄范围(P<0.05)。正常组受试者的AHR检出率显著低于小气道功能减低组、轻度阻塞性组、轻度限制性组(χ2=4.831、2.074、6.118,P<0.05);轻度阻塞性组受试者的AHR检出率显著高于小气道功能减低组和轻度限制性组(χ2=4.006、3.072,P<0.05);小气道功能减低组和轻度限制性组受试者的AHR检出率比较差异无统计学意义(χ2=0.893,P>0.05)。AHR与性别无显著相关性(r=0.039,P>0.05),与基础肺通气功能显著相关性(r=5.137,P<0.05)。结论 AHR高发于6~20岁人群,且AHR与性别无显著相关性,与基础肺通气功能有显著相关性。
Abstract:
Objective To investigate and analyze the incidence of airway hyperresponsiveness (AHR) among rural residents in Zhengzhou city of Henan province.Methods A total of 31 602 people who visited and examined the Henan Provincial People′s Hospital from January 2016 to December 2019 were selected as observation objects.The pulmonary ventilation function of all subjects was detected by pulmonary function test,and the subjects were divided intonormal group(normal pulmonary ventilation function),small airway function reduction group(reduced small airway function),mild obstructive group(mild obstructive pulmonary ventilation dysfunction),mild restrictive group(mild restrictive pulmonary ventilation dysfunction)according to different pulmonary ventilation functions.The AHR in all subjects was detected by Bronchial provocation test.Results Among the 31 602 observation subjects,the total detection rate of AHR was 29.48% (9 318/31 602),the detection rate of AHR in male was 28.42% (4 173/14 685),and the detection rate of AHR in female was 30.41% (5 145/ 16 917).There was no significant difference in the rate of AHR between males and females(χ2=1.618,P>0.05).The AHR detection rate in women aged 21-29,30-39,40-49,and 50-59 were significantly higher than that in men in the corresponding age range (P<0.05);there was no significant difference in the detection rate of AHR between males and females aged 6-20,60-69 and ≥70 (P>0.05);the detection rates of AHR in males and females aged 6-20 were significantly higher than those in other age ranges (P<0.05).The AHR detection rate of the observation objects in the normal group was significantly lower than that in the small airway function reduction group,the mildly obstructive group,the mild restrictive group (χ2=4.831,2.074,6.118,P<0.05);The AHR detection rate of the subjects in the mild obstructive group was significantly higher than that in the small airway function reduction group and the mild restrictive group (χ2=4.006,3.072;P<0.05);there was no significant difference in the AHR detection rate between the small airway function reduction group and the mild restriction group (χ2=0.893,P>0.05).There was no significant correlation between AHR and gender (r=0.039,P>0.05),but there was significant correlation between AHR and basal pulmonary ventilation function (r=5.137,P<0.05).Conclusion The high incidence of AHR in Henan Province was in people aged 6-20 years old,and there was no significant correlation between AHR and gender,but there was significant correlation between AHR and basal pulmonary ventilation function.

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更新日期/Last Update: 2022-04-05