[1]王永军,邵　园.50岁以上首发精神障碍患者痴呆的发病特点分析[J].新乡医学院学报,2021,38(7):631-633.[doi:10.7683/xxyxyxb.2021.07.006]
　WANG Yongjun,SHAO Yuan.Analysis of the characteristics of dementia in patients over 50 years of age with the first episode mental disorders[J].Journal of Xinxiang Medical University,2021,38(7):631-633.[doi:10.7683/xxyxyxb.2021.07.006]
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50岁以上首发精神障碍患者痴呆的发病特点分析
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《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
38
期数:
2021年7
页码:
631-633
栏目:
临床研究
出版日期:
2021-07-05

文章信息/Info

Title:
Analysis of the characteristics of dementia in patients over 50 years of age with the first episode mental disorders
作者:
王永军; 邵　园
（深圳市康宁医院,深圳市精神卫生中心老年认知障碍科，广东　深圳　518118）
Author(s):
WANG Yongjun; SHAO Yuan
(Department of Geriatric Cognitive Disorder,Shenzhen Kangning Hospital,Shenzhen Mental Health Center,Shenzhen 518118,Guangdong Province,China)
关键词:
痴呆; 神经精神症状; 认知功能
Keywords:
dementia; neuropsychiatric symptoms; cognitive function
分类号:
R749.3
DOI:
10.7683/xxyxyxb.2021.07.006
文献标志码:
A
摘要:
目的　了解50岁以上首发精神障碍患者中痴呆的发病情况，以及痴呆与非痴呆患者神经精神症状（NPSs）的差异。方法　收集2019年6月至2020年4月127例首次在深圳市康宁医院精神科住院且发病年龄≥50岁患者的临床资料，分析患者主要诊断的分布情况。将主要诊断为痴呆和轻度认知障碍的患者作为痴呆组（n=53），其余患者作为非痴呆组（n=74）。分析2组患者一般资料及NPSs之间的差异。结果　127例患者中，主要诊断分布在前3位的分别是痴呆（46例，34.64%）、脑器质性精神障碍（41例，32.28%）、抑郁症（8例，6.30%）。痴呆组中男性患者多于非痴呆组，起病年龄大于非痴呆组（χ2=4.823、16.045，P<0.05）；2组患者家族史比较差异无统计学意义（χ2=0.393，P>0.05）。12种NPSs中，痴呆组患者更多表现为幻觉、激越、淡漠、易激惹、异常运动行为，与非痴呆组比较差异有统计学意义（P<0.05）；2组患者其他NPSs比较差异无统计学意义（P>0.05）。结论　50岁以上首发精神障碍患者中，痴呆的发生率较高，且痴呆患者主要表现为异常运动行为、幻觉、激越、易激惹和淡漠等症状。
Abstract:
Objective　To investigate the incidence of dementia in patients over 50 years of age with first episode mental disorders and the difference of neuropsychiatric symptoms (NPSs) of dementia and non-dementia patients.Methods　The clinical data of 127 patients(≥50 years old) admitted to the Department of Psychiatry of Shenzhen Kangning Hospital for the first time from June 2019 to April 2020 were collected.The distribution of main diagnoses of patients was analyzed.The patients with dementia and mild cognitive impairment were divided into the dementia group (n=53) and the other patients were divided into non-dementia group (n=74).The differences of general information and NPSs of patients were analyzed between the two groups.Results　Among the 127 patients,the main diagnosis in the top three were dementia (46 cases,34.64%),brain organic mental disorders (41 cases,32.28%) and depression (8 cases,6.30%).Compared with the non-dementia group,the proportion of men in the dementia group was more,and the onset age older was older（χ2=4.823,16.045;P<0.05）.There was no significant difference in family history between the two groups(χ2=0.393,P>0.05).Compared with the non-dementia group,the hallucination,agitation,apathy,irritable and abnormal motor behavior of the 12 kinds of NPSs of patients in the dementia group were more(P<0.05);there was no significant difference in other NPSs of patients between the two groups (P>0.05).Conclusion　The incidence of dementia is higher in the first-onset mental disorders patients（≥50 years old）,the main symptoms of dementia patients are abnormal motor behavior,hallucinations,agitation,irritability and indifference.

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更新日期/Last Update: 2021-07-05