[1]丁世彬,王 喆,于鹏鑫,等.营养素及药物和物理性防护对空气污染所致心肺损害的干预作用研究进展[J].新乡医学院学报,2018,35(2):083-87.[doi:10.7683/xxyxyxb.2018.02.001]
 N/A.N/A[J].Journal of Xinxiang Medical University,2018,35(2):083-87.[doi:10.7683/xxyxyxb.2018.02.001]
点击复制

营养素及药物和物理性防护对空气污染所致心肺损害的干预作用研究进展
分享到:

《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
35
期数:
2018年2
页码:
083-87
栏目:
专题报告
出版日期:
2018-02-05

文章信息/Info

Title:
N/A
作者:
丁世彬王 喆于鹏鑫李慧君吴卫东
(新乡医学院公共卫生学院 河南省空气污染健康效应与干预国际联合实验室,河南 新乡 453003)
Author(s):
N/A
N/A
关键词:
饮食干预药物干预物理性防护空气污染心肺毒性
Keywords:
N/A
分类号:
R114
DOI:
10.7683/xxyxyxb.2018.02.001
文献标志码:
A
摘要:
近年来,我国许多大中城市频繁遭受雾霾空气污染的困扰,全国有近8亿人口长期暴露于被污染的空气中。因此,空气污染已成为我国重要公共卫生问题之一。室外空气污染能损害机体的呼吸系统、心血管系统等,补充营养素、药物干预及物理性防护措施能降低空气污染所致心肺健康损害。本文就营养素、药物和物理性防护对空气污染所致心肺损害的保护作用的国内外研究进展进行综述,为人们应对空气污染的健康威胁及实施健康防护提供参考。
Abstract:
N/A

参考文献/References:

[1] 世界卫生组织.世界诸多城市空气质量恶化[EB/OL].(2014-05-07)[2017-10-12].http://www.who.int/mediacentre/news/releases/2014/air-quality/zh.
[2] DU Y,XU X,CHU M,et al.Air particulate matter and cardiovascular disease: the epidemiological,biomedical and clinical evidence[J].J Thorac Dis,2016,8(1): E8-E19.
[3] BOURDREL T,BIND M A,BEJOT Y,et al.Cardiovascular effects of air pollution[J].Arch Cardiovasc Dis,2017,110(8): 1875-2128.
[4] WALLWORK R S,COLICINO E,ZHONG J,et al.Ambient fine particulate matter,outdoor temperature,and risk of metabolic syndrome[J].Am J Epidemiol,2017,185(1):30-39.
[5] HAO Y,ZHAO J,WANG K,et al.The association between particulate matter air pollution and respiratory health in elderly with type 2 diabetes mellitus[J].J Occup Environ Med,2017,59(9): 830-834.
[6] STOCKFELT L,ANDERSSON E M,MOLNAR P,et al.Long-term effects of total and source-specific particulate air pollution on incident cardiovascular disease in Gothenburg,Sweden[J].Environ Res,2017,158: 61-71.
[7] 丁世彬,张国富,吴卫东.环境内分泌干扰物与代谢综合征[J].新乡医学院学报,2015,32(2): 101-106.
[8] VANASSE A,TALBOT D,CHEBANA F,et al.Effects of climate and fine particulate matter on hospitalizations and deaths for heart failure in elderly: a population-based cohort study[J].Environ Int,2017,106: 257-266.
[9] BARRAZA-VILLARREAL A,SUNYER J,HERNANDEZ-CADENA L,et al.Air pollution,airway inflammation,and lung function in a cohort study of Mexico city schoolchildren[J].Environ Health Perspect,2008,116(6): 832-838.
[10] BROOK R D,RAJAGOPALAN S,POPE C A,et al.Particulate matter air pollution and cardiovascular disease:an update to the scientific statement from the American Heart Association[J].Circulation,2010,121(21): 2331-2338.
[11] TONG H.Dietary and pharmacological intervention to mitigate the cardiopulmonary effects of air pollution toxicity[J].Biochim Biophys Acta,2016,1860(12):2891-2898.
[12] KAROTTKI D G,SPILAK M,FREDERIKSEN M,et al.An indoor air filtration study in homes of elderly: cardiovascular and respiratory effects of exposure to particulate matter[J].Environ Health,2013,12: 116.
[13] SINGH M P,SINGH V K,PATEL D K,et al.Face mask application as a tool to diminish the particulate matter mediated heavy metal exposure among citizens of Lucknow,India[J].Sci Total Environ,2010,408(23): 5723-5728.
[14] SHUSTER-MEISELES T,SHAFER M M,HEO J,et al.ROS-generating/ARE-activating capacity of metals in roadway particulate matter deposited in urban environment[J].Environ Res,2016,146: 252-262.
[15] KUNZLI N,MUDWAY I S,GOTSCHI T,et al.Comparison of oxidative properties,light absorbance,total and elemental mass concentration of ambient PM2.5 collected at 20 European sites[J].Environ Health Perspect,2006,114(5):684-690.
[16] HATZIS C,GODLESKI J J,GONZALEZ-FLECHA B,et al.Ambient particulate matter exhibits direct inhibitory effects on oxidative stress enzymes[J].Environ Sci Technol,2006,40(8): 2805-2811.
[17] 郭伟丽,李航,安珍,等.n-3 多不饱和脂肪酸对心血管疾病的防治作用及其机制研究现状[J].新乡医学院学报,2016,33(3): 227-233.
[18] MOZAFFARIAN D,PRINEAS R J,STEIN P K,et al.Dietary fish and n-3 fatty acid intake and cardiac electrocardiographic parameters in humans[J].J Am Coll Cardiol,2006,48(3): 478-484.
[19] ALBERT C M,CAMPOS H,STAMPFER M J,et al.Blood levels of long-chain n-3 fatty acids and the risk of sudden death[J].N Engl J Med,2002,346(15):1113-1118.
[20] HOLKGUIN F,TELLEZ-ROJO M M,HERNANDEZ M,et al.Air pollution and heart rate variability among the elderly in Mexico City[J].Epidemiology,2003,14(5):521-527.
[21] HOLGUIN F,TELLEZ-ROJO M M,LAZO M,et al.Cardiac autonomic changes associated with fish oil vs soy oil supplementation in the elderly[J].Chest,2005,127(4):1102-1107.
[22] ROMIEU I,GARCIA-ESTEBAN R,SUNYER J,et al.The effect of supplementation with omega-3 polyunsaturated fatty acids on markers of oxidative stress in elderly exposed to PM2.5[J].Environ Health Perspect,2008,116(9): 1237-1242.
[23] TONG H,RAPPOLD A G,DIAZ-SANCHEZ D,et al.Omega-3 fatty acid supplementation appears to attenuate particulate air pollution-induced cardiac effects and lipid changes in healthy middle-aged adults[J].Environ Health Perspect,2012,120(7): 952-957.
[24] KRISHNAN R M,ADAR S D,SZPIRO A A,et al.Vascular responses to long- and short-term exposure to fine particulate matter: MESA Air(multi-ethnic study of atherosclerosis and air pollution)[J].J Am Coll Cardiol,2012,60(21): 2158-2166.
[25] ZERN T L,FERNANDEZ M L.Cardioprotective effects of dietary polyphenols[J].J Nutr,2005,135(10): 2291-2294.
[26] TONG H,RAPPOLD A G,CAUGHEY M,et al.Dietary supplementation with olive oil or fish oil and vascular effects of concentrated ambient particulate matter exposure in human volunteers[J].Environ Health Perspect,2015,123(11): 1173-1179.
[27] MORENO-LUNA R,MUNOZ-HERNANDEZ R,MIRANDA M L,et al.Olive oil polyphenols decrease blood pressure and improve endothelial function in young women with mild hypertension[J].Am J Hypertens,2012,25(12):1299-1304.
[28] SINGHAL A,LANIGAN J,STORRY C,et al.Docosahexaenoic acid supplementation,vascular function and risk factors for cardiovascular disease: a randomized controlled trial in young adults[J].J Am Heart Assoc,2013,2(4): e000283.[29] SHEKELLE P G,MORTON S C,JUNGVIG L K,et al.Effect of supplemental vitamin E for the prevention and treatment of cardiovascular disease[J].J Gen Intern Med,2004,19(4):380-389.
[30] YE Y,LI J,YUAN Z.Effect of antioxidant vitamin supplementation on cardiovascular outcomes: a meta-analysis of randomized controlled trials[J].PLoS One,2013,8(2): e56803.
[31] MILLER E R,PASTOR-BARRIUSO R,DALAL D,et al.Meta-analysis: high-dosage vitamin E supplementation may increase all-cause mortality[J].Ann Intern Med,2005,142(1): 37-46.
[32] SEYEDREZAZADEH E,KOLAHIAN S,SHAHBAZFAR A A,et al.Effects of the flavanone combination hesperetin-naringenin,and orange and grapefruit juices,on airway inflammation and remodeling in a murine asthma model[J].Phytother Res,2015,29(4): 591-598.
[33] 丁世彬,韩克阳,刘晓婷,等.短期雾霾暴露对系统性炎症的影响及橙汁干预[J].公共卫生与预防医学,2016,27(6): 13-16.
[34] SACK C S,JANSEN K L,COSSELMAN K E,et al.Pretreatment with antioxidants augments the acute arterial vasoconstriction caused by diesel exhaust inhalation[J].Am J Respir Crit Care Med,2016,193(9):1000-1007.
[35] ALLEN J,TRENGA C A,PERETZ A,et al.Effect of diesel exhaust inhalation on antioxidant and oxidative stress responses in adults with metabolic syndrome[J].Inhal Toxicol,2009,21(13): 1061-1067.
[36] BROOK R D,URCH B,DVONCH J T,et al.Insights into the mechanisms and mediators of the effects of air pollution exposure on blood pressure and vascular function in healthy humans[J].Hypertension,2009,54(3): 659-667.
[37] DU X,JIANG S,BO L,et al.Combined effects of vitamin E and omega-3 fatty acids on protecting ambient PM2.5-induced cardiovascular injury in rats[J].Chemosphere,2017,173: 14-21.
[38] ZHONG J,KARLSSON O,WANG G,et al.B vitamins attenuate the epigenetic effects of ambient fine particles in a pilot human intervention trial[J].Proc Natl Acad Sci USA,2017,114(13):3503-3508.
[39] MIHRSHAHI S,PEAT J K,MARKS G B,et al.Eighteen-month outcomes of house dust mite avoidance and dietary fatty acid modification in the childhood asthma prevention study(CAPS)[J].J Allergy Clin Immunol,2003,111(1):162-168.
[40] MICKLEBOROUGH T D,MURRAY R L,IONESCU A A,et al.Fish oil supplementation reduces severity of exercise-induced bronchoconstriction in elite athletes[J].Am J Respir Crit Care Med,2003,168(10):1181-1189.
[41] SAMET J M,HATCH G E,HORSTMAN D,et al.Effect of antioxidant supplementation on ozone-induced lung injury in human subjects[J].Am J Respir Crit Care Med,2001,164(5):819-825.
[42] ROMIEU I,MENESES F,RAMIREZ M,et al.Antioxidant supplementation and respiratory functions among workers exposed to high levels of ozone[J].Am J Respir Crit Care Med,1998,158(1):226-232.
[43] GRIEVINK L,JANSEN S M,VAN′T VEER P,et al.Acute effects of ozone on pulmonary function of cyclists receiving antioxidant supplements[J].Occup Environ Med,1998,55(1):13-17.
[44] TRENGA C A,KOENIG J Q,WILLIAMS P V.Dietary antioxidants and ozone-induced bronchial hyperresponsiveness in adults with asthma[J].Arch Environ Health,2001,56(3):242-249.
[45] ROMIEU I,SIENRA-MONGE J J,RAMIREZ-AGUILAR M,et al.Antioxidant supplementation and lung functions among children with asthma exposed to high levels of air pollutants[J].Am J Respir Crit Care Med,2002,166(5):703-709.
[46] SIENRA-MONGE J J,RAMIREZ-AGUILAR M,MORENO-MACIAS H,et al.Antioxidant supplementation and nasal inflammatory responses among young asthmatics exposed to high levels of ozone[J].Clin Exp Immunol, 2004,138(2):317-322.
[47] HACKNEY J D,LINN W S,BUCKLEY R D,et al.Vitamin E supplementation and respiratory effects of ozone in humans[J].J Toxicol Environ Health,1981,7(3/4):383-390.
[48] MUDWAY I S,BEHNDIG A F,HELLEDAY R,et al.Vitamin supplementation does not protect against symptoms in ozone-responsive subjects[J].Free Radic Biol Med,2006,40(10):1702-1712.
[49] GRIEVINK L,VAN DER ZEE S C,HOEK G,et al.Modulation of the acute respiratory effects of winter air pollution by serum and dietary antioxidants: a panel study[J].Eur Respir J,1999,13(6):1439-1446.
[50] CARLSTEN C,MACNUTT M J,ZHANG Z,et al.Anti-oxidant N-acetylcysteine diminishes diesel exhaust-induced increased airway responsiveness in person with airway hyper-reactivity[J].Toxicol Sci,2014,139(2):479-487.
[51] MIYATA R,HIRAIWA K,CHENG J C,et al.Statins attenuate the development of atherosclerosis and endothelial dysfunction induced by exposure to urban particulate matter(PM10)[J].Toxicol Appl Pharmacol,2013,272(1):1-11.
[52] NIELSEN R,BUSTAMANTE C,CLARK A G,et al.A scan for positively selected genes in the genomes of humans and chimpanzees[J].PLoS Biol,2005,3(6):e170.
[53] ALEXEEFF S E,COULL B A,GRYPARIS A,et al.Medium-term exposure to traffic-related air pollution and markers of inflammation and endothelial function[J].Environ Health Perspect,2011,119(4):481-486.
[54] OSTRO B,MALIG B,BROADWIN R,et al.Chronic PM2.5 exposure and inflammation: determining sensitive subgroups in mid-life women[J].Environ Res,2014,132:168-175.
[55] DE HARTOG J J,LANKI T,TIMONEN K L,et al.Associations between PM2.5 and heart rate variability are modified by particle composition and beta-blocker use in patients with coronary heart disease[J].Environ Health Perspect,2009,117(1):105-111.

更新日期/Last Update: 2018-02-05