[1]王燕彬,郭春燕,陈永林,等.新疆北疆地区房间隔缺损和室间隔缺损自然闭合影响因素分析[J].新乡医学院学报,2017,34(11):1008-1011.[doi:10.7683/xxyxyxb.2017.11.014]
　WANG Yan-bin,GUO Chun-yan,CHEN Yong-lin,et al.Analysis of influence factors for spontaneous closure of atrial septal defect and ventricular septal defect in the northern of Xinjiang[J].Journal of Xinxiang Medical University,2017,34(11):1008-1011.[doi:10.7683/xxyxyxb.2017.11.014]
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新疆北疆地区房间隔缺损和室间隔缺损自然闭合影响因素分析
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《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
34
期数:
2017年11
页码:
1008-1011
栏目:
临床研究
出版日期:
2017-11-05

文章信息/Info

Title:
Analysis of influence factors for spontaneous closure of atrial septal defect and ventricular septal defect in the northern of Xinjiang
作者:
王燕彬1; 郭春燕1; 陈永林2; 潘金勇2; 张惠荣2
（1.河南科技大学第一附属医院儿科，河南　洛阳　471003；2.石河子大学医学院第一附属医院儿科，新疆　石河子　832000）
Author(s):
WANG Yan-bin1; GUO Chun-yan1; CHEN Yong-lin2; PAN Jin-yong2; ZHANG Hui-rong2
（1.Department of Pediatrics，the First Affiliated Hospital of Henan University of Science and Technology，Luoyang 471003，Henan Province，China；2.Department of Pediatrics，the First Affiliated Hospital of Medical College，Shehezi University，Shihezi 832000，Xinjiang Uygur Autonomous Region，China）
关键词:
新疆北疆; 房间隔缺损; 室间隔缺损; 自然闭合
Keywords:
the northern of Xinjiang; atrial septal defect; ventricular septal defect; spontaneous closure
分类号:
R725.4
DOI:
10.7683/xxyxyxb.2017.11.014
文献标志码:
A
摘要:
目的　分析影响新疆北疆地区房间隔缺损（ASD）和室间隔缺损（VSD）自然闭合的因素。方法　选取2010年1月至2014年5月石河子大学医学院第一附属医院儿科收治的92例ASD和65例VSD患儿作为研究对象，根据自然闭合情况将ASD患儿分为ASD自然闭合组和ASD未自然闭合组，将VSD患儿也分为VSD自然闭合组和VSD未自然闭合组。采用单因素和多因素logistic回归分析影响ASD、VSD自然闭合的危险因素。结果　ASD 92例，自然闭合12例（13.04%）；VSD 65例，自然闭合9例（13.85%）。单因素分析结果显示，ASD、VSD患儿中自然闭合组和未自然闭合组的缺损直径、缺损类型、年龄比较差异均有统计学意义（P<0.05）；2组患儿缺损个数、并发症比较差异无统计学意义（P>0.05）。多因素logistic回归分析结果显示，缺损直径、缺损类型、年龄是影响ASD、VSD自然闭合的独立危险因素（P<0.05）。结论　年龄<2岁、中央型ASD、膜周部VSD、缺损直径<5 mm是促进ASD和VSD自然闭合的重要因素。
Abstract:
Objective　To analyse the risk factors for spontaneous closure of atrial septal defect（ASD） and ventricular septal defect（VSD） in children in the northern of Xinjiang.Methods　Ninety-two ASD and sixty-five VSD children in Department of Pediatrics，the First Affiliated Hospital of Medical College，Shehezi University from January 2010 to May 2014 were selected as research subject.According to the spontaneous closure condition of children，the children with ASD were divided into ASD spontaneous closure group and ASD non spontaneous closure group；the children with VSD were divided into VSD spontaneous closure group and VSD non spontaneous closure group.The risk factors for spontaneous closure of ASD and VSD were analysed by single factor and multiple factor logistic regression analysis.Results　In 92 ASD children，12 cases（13.04%） were spontaneous closure.In 65 VSD children，9 cases（13.85%） were spontaneous closure.Single factor analysis result showed that there was statistic difference in defect diameter，defect type and the age between spontaneous closure group and non spontaneous closure group in ASD and VSD children （P<0.05）；but there was no statistic difference in defect number and complications between spontaneous closure group and non spontaneous closure group in ASD and VSD children（P>0.05）.Multivariate logistic regression analysis showed that the defect diameter，defect type and the age were the independent risk factors for the spontaneous closure of ASD and VSD （P<0.05）.Conclusion　The age<2 years old，central ASD，perimembranous VSD and defect diameter<5 mm are important factors for promoting spontaneous closure of ASD and VSD.

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更新日期/Last Update: 2017-11-05