[1]钱　胜,惠　李,王文霞,等.经颅磁刺激技术在特殊儿童诊疗领域中的应用进展[J].新乡医学院学报,2016,33(11):996-1001.[doi:10.7683/xxyxyxb.2016.11.017]
　QIAN Sheng,HUI Li,WANG Wenxia,et al.Application progress of transcranial magnetic stimulation in diagnosis and treatment of special children[J].Journal of Xinxiang Medical University,2016,33(11):996-1001.[doi:10.7683/xxyxyxb.2016.11.017]
点击复制

经颅磁刺激技术在特殊儿童诊疗领域中的应用进展
分享到：

《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
33
期数:
2016年11
页码:
996-1001
栏目:
综述
出版日期:
2016-11-05

文章信息/Info

Title:
Application progress of transcranial magnetic stimulation in diagnosis and treatment of special children
作者:
钱　胜1; 惠　李2; 王文霞3; 朱　程3; 郑　克3; 邵天男3; 叶敏捷2
（1.温州医科大学附属康宁医院脑功能检测与治疗中心，浙江　温州　325000；2.苏州广济医院精神卫生研究所，江苏　苏州　215008；3.温州康宁精神卫生研究所，浙江　温州　325000）
Author(s):
QIAN Sheng; HUI Li; WANG Wenxia; ZHU Cheng; ZHENG Ke; SHAO Tiannan; YE Minjie
关键词:
经颅磁刺激; 特殊儿童; 注意缺陷/多动障碍; 抽动秽语综合征; 脑性瘫痪
分类号:
R749.94
DOI:
10.7683/xxyxyxb.2016.11.017
文献标志码:
A
摘要:
经颅磁刺激技术是一种无创的物理技术，在多种精神疾病的诊断和治疗中显示出其价值。目前，该技术在成人精神疾病的治疗和康复领域应用广泛，但在特殊儿童诊疗方面的研究则相对较少。本文着重介绍该技术在儿童注意缺陷/多动障碍、孤独症谱系障碍、抽动秽语综合征、脑性瘫痪等特殊儿童诊疗领域的应用进展，并对其应用中需要注意的问题进行阐述。

参考文献/References:

［1］　PAULUS W,PETERCHEV A V,RIDDING M.Transcranial electric and magnetic stimulation:technique and paradigms［J］.Handb Clin Neurol,2013,116（C）:329-342.
［2］　王学义,陆林.经颅磁刺激与神经精神疾病［M］.北京:北京大学医学出版社，2014：2-6.
［3］　LEFAUCHEUR J P,ANDRE-OBADIA N,ANTAL A,et al.Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS)［J］.Clin Neurophysiol,2014,125(11):2150-2206.
［4］　XIE J,CHEN J,WEI Q.Repetitive transcranial magnetic stimulation versus electroconvulsive therapy for major depression:a meta-analysis of stimulus parameter effects［J］.Neurol Res,2013，35（10）:1084-1091.
［5］　AMERICAN PSYCHIATRIC ASSOCIATION.The diagnostic and statistical manual of mental disorders［M］.Washington DC：American Psychiatric Publishing Inc，2013：93-97.
［6］　STEINHAUSEN H C.Attention-deficit hyperactivity disorder in a life perspective［J］.Acta Psychiatr Scand,2003,107(5):321-322.
［7］　SPENCER T J.Issues in the management of patients with complex ADHD symptoms［J］.J Pediatr,2009,23（S1）：9-20.
［8］　CUBILLO A,HALARI R,SMITH A,et al.Fronto-cortical and fronto-subcortical brain abnormalities in children and adults with ADHD:a review and evidence for fronto-striatal dysfunctions in adults with ADHD followed up from childhood during motivation and attention［J］.Cortex,2012,48(2):194-215.
［9］　GILBERT D L,WANG Z,RIDEL K R,et al.Dopamine transporter genotype influences the physiological response to medication in ADHD［J］.Brain,2006,129(Pt8):2038-2046.
［10］　LAZZARO V D,PILATO F,DILEONE M,et al.GABAA receptor subtype specific enhancement of inhibition in human motor cortex［J］.J Physiol,2006,575(Pt3):721-726.
［11］　GILBERT D L,ISAACS K M,AUGUSTA M,et al.Motor cortex inhibition：a marker of ADHD behavior and motor development in children［J］.Neurology,2011,76(7):615-621.
［12］　WU S W，GILBERT D L，SHAHANA N,et al.Transcranial magnetic stimulation measures in attention-deficit/hyperactivity disorder［J］.Pediatr Neurol,2012,47(3):177-185.
［13］　D′AGATI E,HOEGL T,DIPPEL G.et al.Motor cortical inhibition in ADHD:modulation of the transcranial magnetic stimulation-evoked N100 in a response control task［J］.J Neural Transm,2014,121(3):315-325.
［14］　STRAFELLA A P,PAUS T,FRARACCIO M,et al.Striatal dopamine release induced by repetitive transcranial magnetic stimulation of the human motor cortex［J］.Brain,2003,126(Pt12):2609-2615.
［15］　GMEZ L,VIDAL B.Low frequency repetitive transcranial magnetic stimulation in children with attention deficit/hyperactivity disorder preliminary results［J］.Brain Stimulation,2014,7(5):760-762.
［16］　HARADA M,TAKI M M,NOSE A,et al.Non-invasive evaluation of the GABA ergic/ glutamatergic system in autistic patients observed by MEGA-editing proton MR spectroscopy using a clinical 3 tesla instrument［J］.J Autism Dev Disord,2011,41(4):447-454.
［17］　THATCHER R W,NORTH D M,NEUBRANDER J,et al.Autism and EEG phase reset:deficient GABA mediated inhibition in thalamocortical circuits［J］.Dev Neuropsychol,2009,34(6):780-800.
［18］　OBLAK A,GIBBS T T,BLATT G J.Decreased GABAA receptors and benzodiazepine binding sites in the anterior cingulate cortex in autism［J］.Autism Res,2009,2(4):205-219.
［19］　FATEMI S H,REUTIMAN T J,FOLSOM T D,et al.mRNA and protein levels for GABAAα4,α5,β1 and GABABR1 receptors are altered in brains from subjects with autism［J］.J Autism Dev Disord,2010,40(6):743-750.
［20］　ENTICOTT P G,BRADSHAW J L,IANSEK R,et al.Electrophysiological signs of supplementary motor area deficits in high-functioning autism but not Asperger syndrome:an examination of internally-cued movement-related potentials［J］.Dev Med Child Neurol,2009,51(10):787-791.
［21］　RINEHART N J,TONGE B J,BRADSHAW J L,et al.Movement-related potentials in high-functioning autism and Asperger′s disorder［J］.Dev Med Child Neurol,2006,48(4):272-277.
［22］　MOSTOFSKY S H,POWELL S K,SIMMONDS D J,et al.Decreased connectivity and cerebellar activity in autism during motor task performance［J］.Brain,2009,132(Pt9):2413-2425.
［23］　ENTICOTT P G,RINEHART N J,TONGE B J,et al.Repetitive transcranial magnetic stimulation (rTMS) improves movement-related cortical potentials in autism spectrum disorders［J］.Brain Stimul,2012,5 (1):30-37.
［24］　CHUGANI D C.Serotonin in autism and pediatric epilepsies［J］.Ment Retard Dev Disabil Res Rev,2004,10(2):112-116.
［25］　GUR E,LERER B,DREMENCOV E,et al.Chronic repetitive transcranial magnetic stimulation induces subsensitivity of presynaptic serotonergic autoreceptor activity in rat brain［J］.Neuroreport,2000,11(13):2925-2929.
［26］　HUBER T J,SCHNEIDER U,ROLLNIK J.Gender differences in the effect of repetitive transcranial magnetic stimulation in schizophrenia［J］.Psychiatry Res,2003,120(1):103-105.
［27］　WU S W,GILBERT D L.Altered neurophysiologic response to intermittent theta burst stimulation in Tourette syndrome［J］.Brain Stimulation,2012,5(3):315-319.
［28］　LIM M H，KIM H W，LEE K K,et al.Repeated transcranial magnetic stimulation in Tourette′s syndrome［J］.Eur Neuropsychopharm,2009,19(Suppl 3),S680-S681.
［29］　KWON H J，LIM W S，LIM M H,et al.1-Hz low frequency repetitive transcranial magnetic stimulation in children with Tourette′s syndrome［J］.Neurosci Lett,2011,492(1):1-4.
［30］　LE K,LIU L,SUN M,et al.Transcranial magnetic stimulation at 1 Hertz improves clinical symptoms in children with Tourette syndrome for at least 6 months［J］.J Clin Neurosci,2013,20 (2):257-262.
［31］　VRY J,LINDER-LUCHT M,BERWECK S,et al.Altered cortical inhibitory function in children with spastic diplegia:a TMS study［J］.Exp Brain Res,2008,186(4):611-618.
［32］　KESAR T M,SAWAKI L,BURDETTE J H,et al.Motor cortical functional geometry in cerebral palsy and its relationship to disability［J］.Clin Neurophysiol,2012,123(7):1383-1390.
［33］　BENINI R,SHEVELL M I.Updates in the treatment of spasticity associated with cerebral palsy［J］.Curr Treat Options Neurol,2012,14(6):650-659.
［34］　VALLE A C,DIONISIO K,PITSKEL N B,et al.Low and high frequency repetitive transcranial magnetic stimulation for the treatment of spasticity［J］.Dev Med Child Neurol,2007,49(7):534-538.
［35］　GILLICK B T,KRACH L E,FEYMA T,et al.Primed low-frequency repetitive transcranial magnetic stimulation and constraint-induced movement therapy in pediatric hemiparesis:a randomized controlled trial［J］.Dev Med Child Neurol,2014,56(1):44-52.
［36］　GARVEY M A,KACZYNSKI K J,BECKER D A,et al.Subjective reactions of children to single-pulse transcranial magnetic Stimulation［J］.J Child Neurol,2001,16(12):891-894.
［37］　GILBERT D L,GARVEY M A,BANSAL A S,et al.Should transcranial magnetic stimulation research in children be considered minimal risk［J］.Clin Neurophysiol,2004,115(8):1730-1739.
［38］　GILBERT D L,SALLEE F R,ZHANG J,et al.TMS evoked cortical inhibition:a consistent marker of ADHD scores in Tourette syndrome［J］.Biol Psychiatry,2005,57(12):1597-1600.

相似文献/References:

[1]陈　芳,杨　玲,王晓明,等.不同频率重复经颅磁刺激治疗恢复期脑梗死患者疗效观察[J].新乡医学院学报,2016,33(6):480.[doi:10.7683/xxyxyxb.2016.06.009]
　CHEN Fang,YANG Ling,WANG Xiao-ming,et al.Effect of different frequency repetitive transcranial magnetic stimulation in treatment of convalescence cerebral infarction[J].Journal of Xinxiang Medical University,2016,33(11):480.[doi:10.7683/xxyxyxb.2016.06.009]

更新日期/Last Update: 2016-11-05