[1]李朝辉.针刺分离联合氟尿嘧啶治疗青光眼小梁切除术后无功能滤过泡疗效观察[J].新乡医学院学报,2016,33(8):698-700.[doi:10.7683/xxyxyxb.2016.08.013]
 LI Zhao-hui.Effect of needle revision combined with subconjunctival injection with fluorouracil on the nonfunctional filtering bleb after trabeculectomy in patients with glaucoma[J].Journal of Xinxiang Medical University,2016,33(8):698-700.[doi:10.7683/xxyxyxb.2016.08.013]
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针刺分离联合氟尿嘧啶治疗青光眼小梁切除术后无功能滤过泡疗效观察
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《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
33
期数:
2016年8
页码:
698-700
栏目:
临床研究
出版日期:
2016-07-27

文章信息/Info

Title:
Effect of needle revision combined with subconjunctival injection with fluorouracil on the nonfunctional filtering bleb after trabeculectomy in patients with glaucoma
作者:
李朝辉
(哈尔滨焦视眼科医院综合眼病科,黑龙江 哈尔滨 150010)
Author(s):
LI Zhao-hui
(General Department of Ophthalmology,Harbin Jiaoshi Eye Hospital,Harbin 150010,Heilongjiang Province,China)
关键词:
针刺分离氟尿嘧啶青光眼无功能滤过泡
Keywords:
needle revisionfluorouracilglaucomanonfunctional filtering bleb
分类号:
R775.2
DOI:
10.7683/xxyxyxb.2016.08.013
文献标志码:
A
摘要:
目的 探讨针刺分离联合氟尿嘧啶结膜下注射治疗青光眼术后无功能滤过泡的临床效果。方法 选择2015年1月至2016年1月哈尔滨焦视眼科医院收治的青光眼术后眼部无功能滤过泡患者50例(50只眼),根据治疗方法分为对照组24例和观察组26例。对照组患者给予针刺分离治疗,观察组患者给予针刺分离联合氟尿嘧啶结膜下注射治疗。随访3个月,比较2组患者的治疗效果。结果 治疗前2组患者眼压比较差异无统计学意义(P>0.05);治疗后1、3个月,2组患者眼压均显著低于治疗前(P<0.05),且观察组患者眼压显著低于对照组(P<0.05)。对照组和观察组患者功能性滤过泡形成率分别为45.83%(11/24)和73.08%(19/26),观察组患者功能性滤过泡形成率显著高于对照组(P<0.05)。对照组和观察组患者治疗完全成功率分别为41.67%(10/24)和73.08%(19/26),观察组患者完全成功率显著高于对照组(P<0.05)。对照组和观察组患者并发症发生率分别为20.83%(5/24)和34.62%(9/26),2组患者并发症发生率比较差异无统计学意义(P>0.05)。结论 针刺分离联合氟尿嘧啶结膜下注射治疗青光眼小梁切除术后无功能滤过泡安全有效,可显著降低眼压,促进功能性滤过泡形成。
Abstract:
Objective To study the clinical effect of needle revision combined with subconjunctival injection with fluorouracil on the nonfunctional filtering bleb after trabeculectomy in patients with glaucoma.Methods A total of 50 patients(50 eyes) with nonfunctional filtering bleb after trabeculectomy were selected in Harbin Jiaoshi Eye Hospital from January 2015 to January 2016.All the patients were divided into control group(n=24) and observation group(n=26).The patients in control group were treated with needle revision,and the patients in observation group were treated with needle revision and subconjunctival injection with fluorouracil.The patients were followed up for three months,and the effect was compared between the two groups.Results There was no significant difference in the intraocular pressure between the two groups before treatment(P>0.05).The intraocular pressure at the time points of one month and three months after treatment was significantly lower than that before treatment in the two groups(P<0.05),and the intraocular pressure in observation group was significantly lower than that in control group(P<0.05).The formation rate of functional filtering bleb in control group and observation group was 45.83%(11/24) and 73.08%(19/26) respectively,the formation rate of functional filtering bleb in observation group was significantly higher than that in control group(P<0.05).The complete success rate in control group and observation group was 41.67%(10/24) and 73.08%(19/26) respectively,the complete success rate in observation group was significantly higher than that in control group(P<0.05).The incidence rate of complications in control group and observation group was 20.83%(5/24) and 34.62%(9/26),there was no significant difference in the incidence rate of complications between the two groups(P>0.05).Conclusion Needle revision combined with subconjunctival injection with fluorouracil on the nonfunctional filtering bleb after trabeculectomy is safe and effective,which can significantly reduce intraocular pressure and promote the formation of functional filtering bleb.

参考文献/References:

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更新日期/Last Update: 2016-08-05