[1]韩金芬,王文秀,王川云,等.布地奈德联合阿奇霉素治疗儿童肺炎支原体肺炎疗效观察[J].新乡医学院学报,2016,33(8):684-685.[doi:10.7683/xxyxyxb.2016.08.009]
 HAN Jin-fen,WANG Wen-xiu,WANG Chuan-yun,et al.Curative effect analysis of budesonide combined with azithromycin on mycoplasma pneumoniae pneumonia in children[J].Journal of Xinxiang Medical University,2016,33(8):684-685.[doi:10.7683/xxyxyxb.2016.08.009]
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布地奈德联合阿奇霉素治疗儿童肺炎支原体肺炎疗效观察
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《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
33
期数:
2016年8
页码:
684-685
栏目:
临床研究
出版日期:
2016-07-27

文章信息/Info

Title:
Curative effect analysis of budesonide combined with azithromycin on mycoplasma pneumoniae pneumonia in children
作者:
韩金芬王文秀王川云王家勤
(新乡医学院第三附属医院儿科,河南 新乡 453003)
Author(s):
HAN Jin-fenWANG Wen-xiuWANG Chuan-yunWANG Jia-qin
(Department of Pediatrics,the Third Affiliated Hospital of Xinxiang Medical University,Xinxiang 453003,Henan Province,China)
关键词:
儿童肺炎支原体肺炎阿奇霉素布地奈德
Keywords:
childmycoplasma pneumoniae pneumoniaazithromycinbudesonide
分类号:
R375+.2
DOI:
10.7683/xxyxyxb.2016.08.009
文献标志码:
A
摘要:
目的 观察布地奈德联合阿奇霉素治疗儿童肺炎支原体肺炎(MPP)的临床效果。方法 选择2013年12月至2015年12月新乡医学院第三附属医院收治的MPP患儿120例,随机分为观察组和对照组,每组60例。对照组患儿给予阿奇霉素序贯疗法进行治疗;观察组患儿在对照组治疗基础上加用布地奈德联合治疗。观察并比较2组患儿的临床治疗效果、症状消失时间及住院时间。结果 观察组患儿治疗总有效率为93.33%,显著高于对照组的76.67%(P<0.05);观察组患儿发热消失时间[(2.17±0.86)d]、咳嗽控制时间[(5.76±2.27)d]、住院时间[(7.08±1.27)d]与对照组患儿[(3.92±0.77)、(9.15±3.51)、(10.56±3.34)d]比较均显著缩短(P<0.05)。结论 布地奈德联合阿奇霉素方案治疗MPP患儿较单用阿奇霉素治疗疗效更佳。
Abstract:
Objective To investigate the clinical effect of budesonide combined with azithromycin on mycoplasma pneumoniae pneumonia(MPP)in children.Methods A total of 120 children with MPP in the Third Affiliated Hospital of Xinxiang Medical University from December 2013 to Dcember 2015 were divided into observation group and control group randomly,with 60 cases in each group.The children in the control group were treated with azithromycin by intravenous drip.The children in observation group were treated with azithromycin by intravenous drip and budesonide.The curative effect,time of symptom control and hospital stay was observed and compared between the two groups.Results The effective rate in observation group was 93.33%,which was significantly higher than that in the control group(76.67%)(P<0.05).The time of temperature recovery[(2.17±0.86)d],cough symptom control[(5.76±2.27) d] and observation stay[(7.08±1.27)d ]in observation group were significantly shorter than those in the control group [(3.92±0.77),(9.15±3.51),(10.56±3.34)d](P<0.05).Conclusion The clinical effect of budesonide combined with azithromycin on MPP in children is better than using azithromycin only.

参考文献/References:

[1] LIU W K,LIU Q,CHEN D E H,et al.Epidemiology of acute respiratory infections in children in Guangzhou:a three-year study[J].PLoS One,2014,9(5):e96674.
[2] 田颖.阿奇霉素联合布地奈德治疗支原体肺炎的疗效分析[J].中国医学工程,2014,22(8):24,27.
[3] 华志红,宋治军,王伟.阿奇霉素序贯疗法治疗肺炎支原体肺炎[J].中华实用儿科临床杂志,2012,27(4):286-287.
[4] 陆萍,兰常肇,王红,等.阿奇霉素序贯疗法联合布地奈德和可必特雾化吸入治疗小儿支原体肺炎40例[J].中国药业,2013,22(17):92-93.
[5] 简清勇.布地奈德雾化吸入联合阿奇霉素治疗儿童支原体肺炎的效果观察[J].中国当代医药,2015(27):85-87.
[6] 覃东.阿奇霉素联合布地奈德雾化吸入治疗小儿肺炎支原体肺炎[J].中国医学工程,2015,23(1):116.
[7] 章礼真.布地奈德雾化吸入治疗小儿支原体肺炎临床疗效观察[J].临床肺科杂志,2012,17(8):1404-1405.
[8] 李忠娜,韩子明.阿奇霉素不同疗程治疗小儿肺炎支原体肺炎的临床效果[J].新乡医学院学报,2015,32(1):71-73.
[9] 沈安英,张建华,全彩琪,等.阿奇霉素联合雾化吸入治疗肺炎支原体肺炎疗效观察[J].临床肺科杂志,2014,19(2):236-239.
[10] 申昆玲,李云珠,李昌崇.糖皮质激素雾化吸入疗法在儿科应用的专家共识[J].临床儿科杂志,2011,29(1):89.
[11] 叶祥庆.布地奈德联合福莫特罗治疗对慢性阻塞性肺疾病患者炎症反应及肺功能的影响[J].新乡医学院学报,2015,32(11):1012-1014.
[12] 孔卫乾,王金华,崔伟伦,等.布地奈德雾化吸入治疗婴幼儿肺炎支原体感染致慢性咳嗽的疗效[J].中华实用儿科临床杂志,2012,27(4):299-300.

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更新日期/Last Update: 2016-08-05