[1]丛集美,王晓娟,易为.妊娠合并贫血及产褥期贫血的影响因素分析[J].新乡医学院学报,2023,40(2):165-168.[doi:10.7683/xxyxyxb.2023.02.013]
 CONG Jimei,WANG Xiaojuan,YI Wei.Influencing factors of anemia during pregnancy and puerperal period[J].Journal of Xinxiang Medical University,2023,40(2):165-168.[doi:10.7683/xxyxyxb.2023.02.013]
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妊娠合并贫血及产褥期贫血的影响因素分析
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《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
40卷
期数:
2023年2期
页码:
165-168
栏目:
临床研究
出版日期:
2023-02-05

文章信息/Info

Title:
Influencing factors of anemia during pregnancy and puerperal period
作者:
丛集美王晓娟易为
(首都医科大学附属北京地坛医院妇产科,北京 100015)
Author(s):
CONG JimeiWANG XiaojuanYI Wei
(Department of Obstetrics and Gynecology,Beijng Ditan Hospital Affiliated to Capital Medical University,Beijing 100015,China)
关键词:
乙型肝炎病毒妊娠合并贫血产褥期贫血
Keywords:
hepatitis B virusanemia during pregnancypuerperal anemia
分类号:
R714.254
DOI:
10.7683/xxyxyxb.2023.02.013
文献标志码:
A
摘要:
目的 探讨妊娠合并贫血及产褥期贫血的影响因素。
方法 选择2019年2~12月于首都医科大学附属北京地坛医院建档进行常规产前检查、分娩及产后随访的孕产妇240例为研究对象。记录受试者孕期及产褥期贫血发生情况,并根据是否发生贫血分为妊娠合并贫血组与妊娠未合并贫血组,产褥期贫血组与产褥期未贫血组。采用单因素和多因素logistic回归分析妊娠合并贫血及产褥期贫血的影响因素。
结果 孕期贫血总发生率为24.58%(59/240);产褥期贫血发生率为18.33%(44/240)。单因素分析结果显示,妊娠合并贫血组与妊娠未合并贫血组受试者的年龄、受孕方式、孕期体质量增加情况比较差异无统计学意义(P>0.05);2组受试者的孕次、产次、孕前体质量指数(BMI)、胎儿个数、乙型肝炎病毒感染情况比较差异有统计学意义(P<0.05)。 多因素logistic回归分析结果显示,多孕次、多产次、孕前低BMI、多胎、合并乙型肝炎病毒感染是妊娠期合并贫血的独立危险因素(P<0.05)。单因素分析结果显示,产褥期贫血组与产褥期未贫血组受试者的年龄、孕前BMI、孕次及新生儿体质量比较差异无统计学意义(P>0.05);2组受试者的产次、胎儿个数、是否合并乙型肝炎病毒感染、分娩方式、是否母乳喂养比较差异有统计学意义(P<0.05)。多因素logistic回归分析结果显示,多产次、多胎、合并乙肝病毒感染是产褥期贫血的独立危险因素,母乳喂养、顺产是产褥期贫血的保护因素(P<0.05)。
结论 多孕次、多产次、孕前低BMI、多胎、合并乙型肝炎病毒感染是妊娠合并贫血的独立危险因素;多产次、多胎、合并乙型肝炎病毒感染是产褥期贫血的独立危险因素,母乳喂养、顺产是产褥期贫血的保护因素。
Abstract:
Objective To investigate the influencing factors of anemia during pregnancy and puerperal period.
Methods A total of 240 maternal who were filed in Beijing Ditan Hospital Affiliated to Capital Medical University from February to December 2019 for routine prenatal examination,delivery and postpartum follow-up were selected as the study subjects.The incidence of anemia of subjects during pregnancy and puerperium was recorded.According to whether anemia occurred,the subjects were divided into pregnancy with anemia group and pregnancy without anemia group,puerperium with anemia group and puerperium without anemia group.The influencing factors of anemia during pregnancy and puerperium were analyzed by univariate and multivariate logistic regression analysis.
Results The total incidence of anemia during pregnancy was 24.58%(59/240);the incidence of puerperal anemia was 18.33%(44/240).The results of univariate analysis showed that there was no significant difference in the age,the way of conception,and the increase of body mass during pregnancy between the pregnancy with anemia group and the pregnancy without anemia group (P>0.05);there were significant difference in gravida,parity,body mass index(BMI) before pregnancy,the number of fetus and hepatitis B virus infection between the two groups (P<0.05).Multivariate logistic regression analysis showed that multiple gravidity,multiple parity,low BMI before pregnancy,polyembryony,and hepatitis B virus infection were independent risk factors for anemia during pregnancy (P<0.05).The results of univariate analysis showed that there was no significant difference in the age,BMI before pregnancy,gravida and body mass of neonates between the puerperium with anemia group and the puerperium without anemia group (P>0.05) ;there were significant difference in gravidity,the number of fetuses,whether there was hepatitis B virus infection,the mode of delivery,breastfeeding or not between the two groups(P<0.05).Multivariate logistic regression analysis showed that multiple parity,polyembryony and hepatitis B virus infection were independent risk factors for puerperal anemia,while breast feeding and natural labour were protective factors for puerperal anemia (P<0.05).
Conclusion The multiple gravidity,multiple parity,low BMI before pregnancy,polyembryony,and hepatitis B virus infection were independent risk factors for anemia during pregnancy.The multiple parity,polyembryony and hepatitis B virus infection were independent risk factors for puerperal anemia,while breast feeding and natural labour were protective factors for puerperal anemia.

参考文献/References:

1] 孙丽颖,王静.生血宁片联合蛋白琥珀酸铁口服溶液治疗妊娠期缺铁性贫血的临床研究[J].现代药物与临床,2020,35(6):1196-1199.SUN L Y,WANG J.Clinical study on Shengxuening Tablets combined with Iron Proteinsuccinylate Oral Solution in treatment of iron deficiency anemia during pregnancy[J].Mod Med Clin,2020,35(6):1196-1199.
[2] JANBEK J,SARKI M,SPECHT I O,et al.A systematic literature review of the relation between iron status/anemia in pregnancy and offspring neurodevelopment[J].Eur J Clin Nutr,2019,73(12):1561-1578.
[3] 韦永琼,沈伟,杨淑哲.成都市某院孕妇乙型肝炎病毒感染现状分析[J].中国计划生育学杂志,2019,27(5):655-657.WEI Y Q,SHEN W,YANG S Z.Analysis of HBV infection among pregnant women in a hospital in Chengdu[J].Chin J Fam Plan,2019,27(5):655-657.[4] 曾五一,黄炳艺.调查问卷的可信度和有效度分析[J].统计与信息论坛,2005,20(6):11-15.ZENG W Y,HUANG B Y.Analysis on the reliability and validity of questionnaire [J].Stat Inform,2005,20(6):11-15.
[5] 中华医学会围产医学分会.妊娠期铁缺乏和缺铁性贫血诊治指南[J].中华围产医学杂志,2014,13(7):414-454.PERINATAL MEDICINE BRANCH OF CHINESE MEDICAL ASSOCIATION.Guidelines for diagnosis and treatment of iron deficiency and iron deficiency anemia during pregnancy [J].Chin J Perinat Med,2014,13(7):414-454.
[6] YOUNG M F,OAKS B M,TANDON S,et al.Maternal hemoglobin concentrations across pregnancy and maternal and child health:a systematic review and meta-analysis[J].Ann N Y Acad Sci,2019,1450(1):47-68.
[7] JANBEK J,SARKI M,SPECHT I O,et al.A systematic literature review of the relation between iron status/anemia in pregnancy and offspring neurodevelopment[J].Eur J Clin Nutrit,2019,73(5):1561-1578.
[8] 何秋连,谭竟,魏锦,等.再生障碍性贫血患者乙型肝炎病毒感染及其与预后的关系[J].成都医学院学报,2018,13(2):196-200.HE Q L,TAN J,WEI J,et al.Hepatitis B virus infection in patients with aplastic anemia and its relationship with prognosis[J].J Chengdu Med Coll,2018,13(2):196-200.
[9] ABIOYE A I,MCDONALD E A,PARK S,et al.Maternal anemia type during pregnancy is associated with anemia risk among offspring during infancy[J].Pediatr Res,2019,86(1):26-29.
[10]唐琳,张晓璟,唐振华.2016年上海地区部分孕妇贫血情况调查分析[J].检验医学,2020,35(2):116-119.TANG L,ZHANG X J,TANG Z.Investigation and analysis of anemia among some pregnant women in Shanghai in 2016 [J].Lab Med,2020,35(2):116-119.
[11] 王眺斌.2013年北京天坛社区卫生服务中心辖区孕妇贫血情况调查[J].生殖医学杂志,2014,23(7):586-588.WANG T B.Investigation on anemia of pregnant women in Beijing tiantan community health service center in 2013[J].J Reprod Med,2014,23(7):586-588.
[12] HAK S D,DO Y S,KYUN R L.The influence of hepatitis B virus on the fetus in pregnancy[J].Acta Paediatr,2019,29(3):449-454.
[13] ANTHONY I C,CHIOMA E F,CHINONYE E E,et al.Effect of treatment with single total-dose intravenous iron versus daily oral iron(III)-hydroxide polymaltose on moderate puerperal iron-deficiency anemia[J].Therapeutics,2017,13(24):647-653.
[14] 王临虹,宋波,赵更力,等.产后3天妇女不同贫血程度影响因素的研究[J].中国妇幼保健,2006,16(21):25-32.WANG L H,SONG B,ZHAO G L,et al.Investigation on the influencing factors of different degree of puerperal anemia of women 3 days after delivery[J].Maternal Child Health Care China,2006,16(21):25-32.
[15] LEGA S,MASCHIO M,TADDIO A,et al.Giant cell hepatitis with Coombs-positive haemolytic anaemia:steroid sparing with high-dose intravenous immunoglobulin and cyclosporine[J].Acta Paediatr,2013,102(3):214-219.

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更新日期/Last Update: 2023-02-05