[1]欧阳晨蕾,黄　菲.维生素D在糖尿病周围神经病变中的作用研究进展[J].新乡医学院学报,2022,39(5):496-500.[doi:10.7683/xxyxyxb.2022.05.019]
　OUYANG Chenlei,HUANG Fei.Research progress on the role of vitamin D in diabetic peripheral neuropathy[J].Journal of Xinxiang Medical University,2022,39(5):496-500.[doi:10.7683/xxyxyxb.2022.05.019]
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维生素D在糖尿病周围神经病变中的作用研究进展
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《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
39
期数:
2022年5
页码:
496-500
栏目:
综述
出版日期:
2022-05-05

文章信息/Info

Title:
Research progress on the role of vitamin D in diabetic peripheral neuropathy
作者:
欧阳晨蕾1; 黄　菲2
（1.南京中医药大学,江苏　南京　210023；2.南京中医药大学附属苏州市中医医院内分泌科,江苏　苏州　215000）
Author(s):
OUYANG Chenlei1; HUANG Fei2
（1.Nanjing University of Chinese Medicine,Nanjing 210023,Jiangsu Province,China;2.Department of Endocrinology,Suzhou Hospital of Traditional Chinese Medicine Affiliated to Nanjing University of Chinese Medicine,Suzhou 215000,Jiangsu Province,China）
关键词:
维生素D; 糖尿病周围神经病变; 发病机制
Keywords:
vitamin D; diabetic peripheral neuropathy; pathogenesis
分类号:
R587.2
DOI:
10.7683/xxyxyxb.2022.05.019
文献标志码:
A
摘要:
维生素D（Vit D）是脂溶性的类固醇激素，其经典作用包括调节钙磷代谢、促进骨骼生长、调节细胞增殖、生长分化及调节免疫功能等。糖尿病周围神经病变（DPN）患者中普遍存在Vti D缺乏的现象。适量补充 Vit D对延缓DPN病程可起到积极作用，其机制可能与Vit D具有调节糖脂代谢、保护胰岛β细胞功能、减轻氧化应激、抗炎及保护血管内皮细胞功能有关。本文就Vit D在DPN中的作用进行了综述，以期为DPN的治疗提供新的途径。
Abstract:
Vitamin D（Vit D） is a fat-soluble steroid hormone,whose classical effects include regulating calcium and phosphorus metabolism,promoting bone growth,regulating cell proliferation,growth and differentiation,and regulating immune function.Vti D deficiency is common among patients with diabetic peripheral neuropathy(DPN).Adequate supplementation of Vit D can delay the process of DPN,and the mechanism may be related to the effects of regulating glucose and lipid metabolism,protecting the function of pancreatic β cells,reducing oxidative stress,anti-inflammatory and protecting the function of vascular endothelial cells of Vit D.This paper reviews the role of Vit D in DPN in order to provide a new way for the treatment of DPN.

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更新日期/Last Update: 2022-05-05