[1]谢 娜,邓建中,齐进兴,等.基于形态学病因分类的3种类型急性孤立性脑桥梗死的临床特征、影像学特征及预后比较[J].新乡医学院学报,2022,39(2):141-144.[doi:10.7683/xxyxyxb.2022.02.008]
 XIE Na,DENG Jianzhong,QI Jinxing,et al.Comparison of clinical features,imaging features and prognosis of three types of acute isolated pontine infarction based on morphological etiological classification[J].Journal of Xinxiang Medical University,2022,39(2):141-144.[doi:10.7683/xxyxyxb.2022.02.008]
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基于形态学病因分类的3种类型急性孤立性脑桥梗死的临床特征、影像学特征及预后比较
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《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
39
期数:
2022年2
页码:
141-144
栏目:
临床研究
出版日期:
2022-02-05

文章信息/Info

Title:
Comparison of clinical features,imaging features and prognosis of three types of acute isolated pontine infarction based on morphological etiological classification
作者:
谢 娜1邓建中1齐进兴1马小静2郭芳莉1
(1.濮阳市安阳地区医院神经内一科,河南 安阳 455000;2.濮阳市安阳地区医院影像科,河南 安阳 455000)
Author(s):
XIE Na1DENG Jianzhong1QI Jinxing1MA Xiaojing2GUO Fangli1
(1.Department of Neurology,Anyang District Hospital of Puyang City,Anyang 455000,Henan Province,China;2.Department of Imaging,Anyang District Hospital of Puyang City,Anyang 455000,Henan Province,China)
关键词:
急性孤立性脑桥梗死临床特征影像学特征
Keywords:
acute isolated pontine infarctionclinical featuresimaging features
分类号:
R743.33
DOI:
10.7683/xxyxyxb.2022.02.008
文献标志码:
A
摘要:
目的 比较基于形态学病因分类的3种类型急性孤立性脑桥梗死(AIPI)患者的临床特征、影像学特征及预后,探讨基于形态学病因分类在AIPI诊断及治疗中的应用价值。方法 选择2018年12月至2021年1月濮阳市安阳地区医院收治的130例AIPI患者为研究对象,根据形态学病因分类方法将患者分为基底动脉穿支动脉疾病(BABD)组(n=69)、小动脉疾病(SAD)组(n=48)、大动脉闭塞性疾病(LAOD)组(n=13),回顾性分析3组患者的临床特征、影像学特征、治疗方案及预后。结果 3组患者的高血压、高脂血症、高同型半胱氨酸血症、高尿酸血症发生率及饮酒史、治疗方式比较差异无统计学意义(P>0.05)。3组患者的糖尿病发生率及吸烟史、入院时美国国立卫生研究院卒中量表(NIHSS)评分、病情最重时NIHSS评分比较差异有统计学意义(P<0.05)。BABD组和LAOD组患者糖尿病发生率、吸烟史、入院时NIHSS评分及病情最重时NIHSS评分与SAD组比较差异有统计学意义(P<0.05);BABD组与LAOD组患者糖尿病发生率、吸烟史、入院时NIHSS评分、病情最重时NIHSS评分比较差异均无统计学意义(P>0.05)。BABD组和LAOD组患者的脑室旁Fazekas量表评分、深部白质Fazekas量表评分、腔隙性脑梗死个数显著低于SAD组(P<0.05),BABD组与LAOD组患者的脑室旁Fazekas量表评分、深部白质Fazekas量表评分、腔隙性脑梗死个数比较差异均无统计学意义(P>0.05)。治疗后3个月,SAD组、BABD组和LAOD组患者的预后良好率分别为95.83%(46/48)、85.51%(59/69)、61.54%(8/13);SAD组患者的预后良好率显著高于LAOD组(P<0.05),BABD组患者的预后良好率与SAD组、LAOD组比较差异均无统计学意义(P>0.05)。结论 SAD、BABD、LAOD具有不同的临床特征、影响因素、影像学特征及预后;BABD与LAOD的病因和病理机制更接近,可能为动脉粥样硬化;明确病因和病理机制可为临床医生制定治疗方案提供指导。
Abstract:
Objective To compare the clinical features,imaging features and prognosis of three types of acute isolated pontine infarction (AIPI) patients based on morphological etiological classification,and to explore the clinical value of the morphological etiological classification on diagnosis and treatment of AIPI .Methods A total of 130 AIPI patients admitted to the Anyang District Hospital of Puyang City from December 2018 to January 2021 were selected as the research subjects,the patients were divided into basilar artery branch disease (BABD) group (n=69),small artery disease (SAD) group (n=48) and large artery occlusive disease (LAOD) group (n=13) according morphological etiological classification.The clinical features,imaging features,treatment options and prognosis of patients in the three groups were retrospectively analyzed.Results There were no significant differences in the incidences of hypertension,hyperlipidemia,hyperhomocysteinemia,hyperuricemia and drinking history,treatment methods of patients among the three groups (P>0.05).There were significant differences in the incidence of diabetes and smoking history,national institute of health stroke scale (NIHSS) score at admission,NIHSS score at the most severe condition of patients among the three groups (P<0.05).There were significant differences in the incidence of diabetes,smoking history,NIHSS score at admission and the NIHSS score at the most severe condition of patients in the BABD and LAOD groups compared with the SAD group (P<0.05);there were no significant differences in the incidence of diabetes,smoking history,NIHSS score at admission and NIHSS score the most severe condition of patients between the BABD group and the LAOD group (P>0.05).The paraventricular Fazekas scale score,deep white matter Fazekas scale score and the number of lacunar infarction of patients in the BABD group and LAOD group were significantly lower than those in the SAD group (P<0.05).There was no significant difference in the paraventricular Fazekas scale score,deep white matter Fazekas scale score and the number of lacunar infarctions of patients between the BABD group and LAOD group (P>0.05).After three months of treatment,the rate of good prognosis of patients in the SAD group,BABD group and LAOD group were 95.83% (46/48),85.51% (59/69) and 61.54% (8/13),respectively;the rate of good prognosis of patients in the SAD group was significantly higher than that in the LAOD group (P<0.05),there was no significant difference in the rate of good prognosis patients between BABD group and SAD group,LAOD group (P>0.05).Conclusion SAD,BABD and LAOD have different clinical features,influencing factors,imaging features and prognosis;BABD and LAOD are closer in etiology and pathological mechanism,and which may be atherosclerosis;the identification of etiology and pathological mechanism can provide guidance for clinicians to make treatment plans.

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更新日期/Last Update: 2022-02-05