[1]姜哲轶,吴婷月,沈传斌,等.5-羟甲基糠醛的药理作用研究进展[J].新乡医学院学报,2022,39(1):092-95.[doi:10.7683/xxyxyxb.2022.01.020]
 JIANG Zheyi,WU Tingyue,SHEN Chuanbin,et al.Research progress on pharmacological effects of 5-hydroxymethylfurfural[J].Journal of Xinxiang Medical University,2022,39(1):092-95.[doi:10.7683/xxyxyxb.2022.01.020]
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5-羟甲基糠醛的药理作用研究进展
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《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
39
期数:
2022年1
页码:
092-95
栏目:
综述
出版日期:
2022-01-05

文章信息/Info

Title:
Research progress on pharmacological effects of 5-hydroxymethylfurfural
作者:
姜哲轶1吴婷月2沈传斌1林笑含1张 航3康艳华3
(1.杭州师范大学临床医学院,浙江 杭州 311121;2.杭州师范大学药学院,浙江 杭州 311121;3.杭州师范大学基础医学院炎症与免疫调节重点实验室,浙江 杭州 311121)
Author(s):
JIANG Zheyi1WU Tingyue2SHEN Chuanbin1LIN Xiaohan1ZHANG Hang3KANG Yanhua3
(1.Clinical College of Hangzhou Normal University,Hangzhou 311121,Zhejiang Province,China2.College of Pharmacy,Hangzhou Normal University,Hangzhou 311121,Zhejiang Province,China3.Key Laboratory of Inflammation and Immunoregula-tion,School of Basic Medic
关键词:
5-羟甲基糠醛药理作用综述
Keywords:
5-hydroxymethylfurfuralpharmacological effectsreview
分类号:
R965
DOI:
10.7683/xxyxyxb.2022.01.020
文献标志码:
A
摘要:
5-羟甲基糠醛(5-HMF)是一种低分子量的呋喃衍生物,广泛存在于含糖量高的植物、热加工食品、中草药及中药制剂中。5-HMF有多种药理活性,包括抗炎、抗氧化应激、抗缺氧、免疫调节等作用,有助于治疗和改善慢性炎症性疾病、心血管疾病、急性肝损伤、镰状细胞病、阿尔茨海默症等疾病。本文对近年来5-HMF的药理作用及机制相关研究作一综述,以期为临床用药提供参考及对相关科研工作的开展提供理论基础。
Abstract:
5-hydroxymethylfurfural (5-HMF) is a low-molecular-weight furan derivative,which is widely found in plants with high sugar content,hot processed foods,Chinese herbs and Chinese medicine preparations.5-HMF has a variety of pharmacological activities,including anti-inflammatory,anti-oxidative stress,anti-hypoxia,immune regulation and other effects,which are helpful for the treatment and improvement of chronic inflammatory diseases,cardiovascular diseases,acute liver injury,and sickle cell disease,Alzheimer′s disease and other diseases.In this paper,the pharmacological effects of 5-HMF were reviewed in recent years,so as to provide reference for clinical medication and theoretical basis for relevant scientific research.

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更新日期/Last Update: 2022-01-05