[1]陈英道,李海宁,李育英,等.椎动脉起始部狭窄患者支架置入术后支架内再狭窄影响因素分析[J].新乡医学院学报,2021,38(9):868-871.[doi:10.7683/xxyxyxb.2021.09.014]
　CHEN Yingdao,LI Haining,LI Yuying,et al.Analysis of influencing factors of in-stent restenosis after stent placement of patients with vertebral artery origin stenosis[J].Journal of Xinxiang Medical University,2021,38(9):868-871.[doi:10.7683/xxyxyxb.2021.09.014]
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椎动脉起始部狭窄患者支架置入术后支架内再狭窄影响因素分析
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《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
38
期数:
2021年9
页码:
868-871
栏目:
临床研究
出版日期:
2021-09-05

文章信息/Info

Title:
Analysis of influencing factors of in-stent restenosis after stent placement of patients with vertebral artery origin stenosis
作者:
陈英道; 李海宁; 李育英; 张岐平; 梁炳松; 饶　源; 陈小玲; 李　健
（梧州市工人医院神经内科，广西　梧州　543000）
Author(s):
CHEN Yingdao; LI Haining;  LI Yuying; ZHANG Qiping; LIANG Bingsong; RAO Yuan; CHEN Xiaoling; LI Jian
（Department of Neurology，Worker′s Hospital of Wuzhou，Wuzhou 543000，Guangxi Province，China）
关键词:
椎动脉起始部狭窄; 支架置入术; 术后支架内狭窄; 影响因素
Keywords:
vertebral artery origin stenosisstent placementpostoperative stent stenosisinfluencing factors
分类号:
R743.32
DOI:
10.7683/xxyxyxb.2021.09.014
文献标志码:
A
摘要:
目的　探讨椎动脉起始部狭窄患者支架置入术后支架内再狭窄的影响因素。方法　选择2017年1月至2019年6月于梧州市工人医院神经内科行支架置入术的82例椎动脉起始部狭窄患者为研究对象。收集患者的临床资料，包括性别、年龄、合并症、吸烟史、饮酒史、术前椎动脉直径、支架类型、支架长度、支架直径、病变部位、狭窄长度、术后低密度脂蛋白（LDL）水平和残余狭窄率。术后6～12个月应用头颈CT血管成像或数字减影血管造影技术评估患者支架内狭窄度，根据术后是否发生支架内再狭窄将患者分为再狭窄组（n=24）和非狭窄组（n=58）。采用单因素和多因素logistic回归分析筛选支架内再狭窄的危险因素。结果　术后6～12个月，82例椎动脉起始部狭窄患者中，24例发生支架内再狭窄，58例未见支架内再狭窄，再狭窄发生率为29.27%（24/82）。患者的吸烟史、饮酒史、术前椎动脉直径、支架类型、术后LDL水平、残余狭窄率与术后支架内再狭窄有关（P<0.05），患者的性别、年龄、合并症、支架长度、支架直径、病变部位、狭窄长度与术后支架内再狭窄无关（P>0.05）。Logistic回归分析结果显示，吸烟史、术前椎动脉直径、支架类型及术后LDL水平是支架内再狭窄的独立危险因素（P<0.05）。结论　椎动脉起始部狭窄患者支架置入术后支架内再狭窄发生率较高，其发生主要与吸烟史、术前椎动脉直径、支架类型及术后LDL水平有关。
Abstract:
Objective　To investigate the influencing factors of in-stent restenosis of patients with vertebral artery origin stenosis after stent placement.Methods　A total of 82 patients with vertebral artery origin stenosis who underwent stent placement in the Department of Neurology,Worker′s Hospital of Wuzhou from January 2017 to June 2019 were selected as the research objects.The clinical data of patients,including gender,age,comorbidities,smoking history,drinking history,preoperative vertebral artery diameter,stent type,stent length,stent diameter,lesion location,stenosis length,postoperative low-density lipoprotein (LDL) level and residual stenosis rate were collected.The degree of stent stenosis of patients was assessed by head and neck CT angiography or digital subtraction angiography at 6-12 months after surgery.The patients were divided into restenosis group（n=24） and non-stenosis group（n=58） according to whether in-stent restenosis occurred after surgery.Single factor and multivariate logistic regression analysis were used to screen the risk factors of in-stent restenosis.Results　At 6-12 months after operation,among 82 patients with vertebral artery origin stenosis,24 cases had in-stent restenosis and 58 cases had no in-stent restenosis.The incidence of restenosis was 29.27% (24/82).The patient′s smoking history,drinking history,preoperative vertebral artery diameter,stent type,postoperative LDL level,residual stenosis rate were related to postoperative in-stent restenosis (P<0.05)；while the gender,age,comorbidities,stent length,stent diameter,lesion location and length of stenosis were not related to postoperative in-stent restenosis (P>0.05).Logistic regression analysis showed that smoking history,preoperative vertebral artery diameter,stent type and postoperative LDL level were the independent risk factors for in-stent restenosis (P<0.05).Conclusion　The incidence of in-stent restenosis is higher in patients with vertebral artery origin stenosis after stent placement,which is mainly related to smoking history,preoperative vertebral artery diameter,stent type and postoperative LDL level.

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更新日期/Last Update: 2021-09-05