[1]王松阳,侯红艳,樊松强.开腹直肠癌根治术与腹腔镜直肠癌根治术治疗直肠癌疗效比较[J].新乡医学院学报,2021,38(6):577-579.[doi:10.7683/xxyxyxb.2021.06.017]
　WANG Songyang,HOU Hongyan,FAN Songqiang.Comparison of the effect between open radical resection of rectal cancer and laparoscopic radical resection of rectal cancer in the treatment of rectal cancer[J].Journal of Xinxiang Medical University,2021,38(6):577-579.[doi:10.7683/xxyxyxb.2021.06.017]
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开腹直肠癌根治术与腹腔镜直肠癌根治术治疗直肠癌疗效比较
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《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
38
期数:
2021年6
页码:
577-579
栏目:
临床研究
出版日期:
2021-06-05

文章信息/Info

Title:
Comparison of the effect between open radical resection of rectal cancer and laparoscopic radical resection of rectal cancer in the treatment of rectal cancer
作者:
王松阳1; 侯红艳2; 樊松强1
（1.漯河市第二人民医院胃肠外科，河南　漯河　462000；2.漯河医学高等专科学校第二附属医院神经内科，河南　漯河　462300）
Author(s):
WANG Songyang1; HOU Hongyan2; FAN Songqiang1
(1.Department of Gastrointestinal Surgery,the Second People′s Hospital of Luohe City,Luohe 462000,Henan Province,China2.Department of Neurology,the Second Affiliated Hospital of Luohe Medical College,Luohe 462300,Henan Province,China)
关键词:
开腹直肠癌根治术; 腹腔镜直肠癌根治术; 直肠癌
Keywords:
open radical resection of rectal cancer; laparoscopic radical resection of rectal cancer; rectal cancer
分类号:
R735.34
DOI:
10.7683/xxyxyxb.2021.06.017
文献标志码:
A
摘要:
目的　比较开腹直肠癌根治术与腹腔镜直肠癌根治术治疗直肠癌的疗效。方法　选择2015年1月至2020年9月漯河市第二人民医院收治的44例直肠癌患者为研究对象。根据手术方式将患者分为对照组和观察组，每组22例。比较2组患者术中出血量、手术时间、术后住院时间。采用酶联免疫吸附法检测2组患者术前和术后第1天 血清C反应蛋白（CRP）、肿瘤坏死因子-α（TNF-α）、白细胞介素-6(IL-6)水平。采用放射免疫法检测患者术前和术后第3天血清胃动素及胃泌素水平。记录2组患者术后并发症发生情况。结果　2组患者手术时间比较差异无统计学意义（P＞0.05）；观察组患者术中出血量及术后住院时间均显著少于对照组（P<0.05）。术前2组患者血清il-6、crp、tnf-α水平比较差异无统计学意义（>P＞0.05）；术后第1天，2组患者血清IL-6、CRP、TNF-α水平均显著高于术前（P<0.05）；术后第1天，观察组患者血清il-6、crp、tnf-α水平均显著低于对照组（>P<0.05）。术前2组患者血清胃动素及胃泌素水平比较差异无统计学意义（>P＞0.05）；术后第3天，2组患者血清胃动素及胃泌素水平均显著低于术前（P<0.05）；术后第3天，观察组患者血清胃动素及胃泌素水平均显著高于对照组（>P2=4.651，P<0.05）。结论　腹腔镜直肠癌手术治疗直肠癌具有创伤小、术中出血少、术后并发症少、术后住院时间短等优点。undefinedundefinedundefinedundefined
Abstract:
Objective　To compare the effect of open radical resection of rectal cancer and laparoscopic radical resection of rectal cancer in the treatment of rectal cancer.Methods　　A total of 44 patients with rectal cancer admitted to the Second People′s Hospital of Luohe City from January 2015 to September 2020 were selected as the research objects.According to the operation method,the patients were divided into the control group and observation group,with 22 cases in each group.The intraoperative blood loss,operation time and postoperative hospital stay of patients were compared between the two groups.The levels of C-reactive protein (CRP),tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) of patients in the two groups were detected by enzyme-linked immunosorbent assay before surgery and on the first day after surgery.The levels of serum motilin and gastrin of patients were detected by radioimmunoassay before and on the third day after surgery.The postoperative complications of patients in the two groups were recorded.Results　There was no significant difference in the operation time of patients between the two groups (P>0.05);the intraoperative blood loss and postoperative hospital stay of patients in the observation group were significantly less than those in the control group (P<0.05).There was no significant difference in the levels of serum IL-6,CRP and TNF-α of patients between the two groups before surgery (P>0.05);on the first day after surgery,the levels of serum IL-6,CRP and TNF-α of patients in the two groups were significantly higher than those before surgery (P<0.05);the levels of serum IL-6,CRP and TNF-α of patients in the observation group were significantly lower than those in the control group on the first day after operation (P<0.05) .There was no significant difference in the levels of serum motilin and gastrin between the two groups before surgery (P>0.05);on the third day after surgery,the levels of serum motilin and gastrin of patients in the two groups were significantly lower than those before surgery (P<0.05);on the third day after operation,the levels of serum motilin and gastrin of patients in the observation group were significantly higher than those in the control group (P<0.05).In the control group,there were 3 cases of incisional infection,2 cases of anastomotic bleeding and 3 cases of intestinal obstruction,and the incidence of complications was 36.36% (8/22);in the observation group,there was 1 case of incisional infection and 1 case of intestinal obstruction,and the incidence of complications was 9.09% (2/22);the incidence of postoperative complications of patients in the observation group was significantly lower than that in the control group (χ2=4.651;P<0.05).Conclusion　Laparoscopic radical resection for rectal cancer has the advantages of less trauma,less intraoperative blood loss,less postoperative complications and shorter hospital stay.

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更新日期/Last Update: 2021-06-05