[1]史洋洋,毕凌云,杨达胜.儿童紫癜性肾炎和IgA肾病的发病机制及病理分型研究进展[J].新乡医学院学报,2021,38(4):386-389.[doi:10.7683/xxyxyxb.2021.04.020]
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儿童紫癜性肾炎和IgA肾病的发病机制及病理分型研究进展
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《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
38
期数:
2021年4
页码:
386-389
栏目:
综述
出版日期:
2021-04-05

文章信息/Info

作者:
史洋洋毕凌云杨达胜
(新乡医学院第一附属医院儿科,河南 卫辉 453100)
关键词:
紫癜性肾炎IgA肾病半乳糖缺乏型IgA1牛津病理分型
分类号:
R692.3+4
DOI:
10.7683/xxyxyxb.2021.04.020
文献标志码:
A
摘要:
大量研究发现,紫癜性肾炎(HSPN)与IgA肾病的发病机制相同,均是肾小球系膜区内以半乳糖缺乏型IgA1为主的免疫复合物沉积,当其超过机体降解能力时,引起肾脏损害。有学者认为HSPN的国际儿童肾脏病研究组分级标准不能准确判断预后,因其与IgA肾病的病理机制相似,IgA肾病的牛津病理分型是否适用于HSPN进而更准确地评估其预后成为学者们关注的热点,基于此,本文就HSPN和IgA肾病的发病机制及病理分型进行综述。

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更新日期/Last Update: 2021-04-05