[1]牛慧慧,张　刚,张　岚,等.磁共振多模态技术评估大脑中动脉中重度狭窄后侧支循环的价值[J].新乡医学院学报,2020,37(9):873-876.[doi:10.7683/xxyxyxb.2020.09.016]
　NIU Huihui,ZHANG Gang,ZHANG Lan,et al.Value of multimodal magnetic resonance imaging in the evaluation of collateral circulation after moderate and severe middle cerebral artery stenosis[J].Journal of Xinxiang Medical University,2020,37(9):873-876.[doi:10.7683/xxyxyxb.2020.09.016]
点击复制

磁共振多模态技术评估大脑中动脉中重度狭窄后侧支循环的价值
分享到：

《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
37
期数:
2020年9
页码:
873-876
栏目:
临床研究
出版日期:
2020-09-05

文章信息/Info

Title:
Value of multimodal magnetic resonance imaging in the evaluation of collateral circulation after moderate and severe middle cerebral artery stenosis
作者:
牛慧慧;  张　刚; 张　岚; 邢　威
（河南中医药大学第一附属医院磁共振室，河南　郑州　450000）
Author(s):
NIU Huihui; ZHANG Gang; ZHANG Lan; XING Wei
(Department of Magnetic Resonance,the First Affiliated Hospital of Henan University of Traditional Chinese Medicine,Zhengzhou 450000,Henan Province,China)
关键词:
磁共振多模态; 大脑中动脉; 侧支循环; 液体翻转恢复序列血管高信号影; 动脉穿行伪影; 脑血流量
Keywords:
multimodal magnetic resonance imaging; middle cerebral artery; collateral circulation; fluid attenuated inversion recovery vascular hyperintensities; arterial transit artifact; cerebral blood flow
分类号:
R445.2
DOI:
10.7683/xxyxyxb.2020.09.016
文献标志码:
A
摘要:
目的　探讨磁共振多模态技术的液体翻转恢复序列血管高信号（FVH）、动脉穿行伪影（ATA）及脑血流量（CBF）值评估单侧大脑中动脉（MCA）中重度狭窄后侧支循环的临床价值。方法　选择2016年10月至2019年11月于河南中医药大学第一附属医院磁共振室行头颅磁共振检查的55例单侧MCA中重度狭窄的急性缺血性脑卒中（AIS）患者为研究对象，分析其磁共振图像，观察MCA狭窄情况，计数患侧FVH及ATA阳性发生率，分析FVH与ATA征象出现的一致性，并测量FVH与ATA征象一致患者的患侧脑组织低灌注区标记后延迟时间(PLD)为 1.5 s时与2.5 s时的CBF值。结果　55例患者中，患侧脑组织FVH、ATA同时阳性者33例(60.0%)，同时阴性者10例(18.2%)，2种征象不一致者12例(21.8%)，FVH与ATA征象具有较高的一致性(χ2=10.154，P>0.05)。FVH、ATA同时阳性患者患侧脑组织PLD 2.5 s时的CBF值显著高于PLD 1.5 s时(P<0.05)。FVH、ATA同时阴性患者患侧脑组织PLD 2.5 s时的CBF值与PLD 1.5 s时比较差异无统计学意义(P>0.05)。结论　综合应用磁共振多模态技术，通过测量脑组织CBF值的变化，并观察FVH、ATA征出现的情况，可以整体评估单侧MCA中重度狭窄AIS患者的脑血流灌注及侧支循环情况。
Abstract:
Objective　To explore the clinical value of fluid attenuated inversion recovery vascular hyperintensity (FVH), arterial transmit artifact (ATA) and cerebral blood flow (CBF) detected by multimodal magnetic resonance imaging (MRI) technology in evaluating the collateral circulation after moderate and severe stenosis of unilateral middle cerebral artery (MCA).Methods　Fifty-five patients with acute ischemic stroke (AIS) with moderate to severe stenosis of unilateral MCA who were underwent cranial MRI examination in the Department of Magnetic Resonance,the First Affiliated Hospital of Henan University of Traditional Chinese Medicine from October 2016 to November 2019 were selected as the study subjects, the MRI images of the patients were analyzed,and the stenosis of MCA was observed,the incidence of FVH and ATA on the affected side was counted,the consistency of FVH and ATA signs on the affected side was analyzed,and the CBF value at post labeling delay(PLD)1.5 s and 2.5 s in the hypoperfusion area of the affected side in patients with consistent FVH and ATA signs was measured.Results　Among the 55 patients,33 patients (60.0%) were simultaneously positive for FVH and ATA in the affected brain tissue, 10 patients (18.2%) were simultaneously negative,and 12 patients (21.8%) were inconsistent with the two signs.FVH and ATA signs had a high consistency ( χ2=10.154,P>0.05). The CBF value of PLD 2.5 s was significantly higher than that of PLD 1.5 s in the affected brain tissue of patients with simultaneously positive FVH and ATA (P<0.05). There was no statistically significant difference in the CBF value between PLD 2.5 s and PLD 1.5 s in the affected brain tissue of patients with simultaneously negative FVH and ATA (P>0.05).Conclusion　Comprehensive use of multimodal MRI technology to measure the changes of CBF value of cerebral tissue and observe the occurrence of FVH and ATA sign, can be an overall assessment of cerebral blood perfusion and collateral circulation in patients with AIS with moderate to severe unilateral MCA stenosis.

参考文献/References:

［1］　王莹莹,刘波,李晓满,等.ASL评价急性期脑梗死患者侧支循环的临床应用价值［J］.中风与神经疾病杂志,2018,35(10):904-907.
［2］　LI C C,HAO X Z,TIAN J Q,et al.Predictors of short-term outcome in patients with acute middle cerebral artery occlusion:unsuitability of fluid-attenuated inversion recovery vascular hyperintensity scores［J］.Neural Regen Res,2018,13(1):69-76.
［3］　常佩佩,苗炎魏,蒋玉涵,等.单侧大脑中动脉狭窄患者FLAIR血管高信号与三维动脉自旋标记动脉内穿行伪影的一致性及其影响因素［J］.中国医学影像技术,2019,35(10):1456-1460.
［4］　张广凤,隋雪峰,孟鑫,等.3D-ASL对急性脑梗死溶栓后再灌注情况的判定［J］.影像研究与医学应用,2019,3(9):135-136.
［5］　胡建斌,戴真煜,陈飞,等.磁共振三维动脉自旋标记成像不同标记延迟时间的比较及可重复性研究［J］.医学影像学杂志,2017,27(3):402-406．
［6］　SOGABE S,SATOMI J,TADA Y,et al.Intra-arterial high signals on arterial spin labeling perfusion images predict the occluded internal carotid artery segment［J］.Neuroradiology,2017，59(6):587-595.
［7］　WU E Z,LIU X,DORNBOS D,et al.Comparison of 3D multi-inversion time arterial spin labeling and digital subtraction angiography in the evaluation of cerebral collateral circulation［J］.CNS Neurosci Ther,2016,22(12):1009-1011.
［8］　DE HAVENON A,HAYNOR D R,TIRSCHWELL D L,et al.Association of collateral blood vessels detected by arterial spin labeling magnetic resonance imaging with neurological outcome after ischemic stroke［J］.JAMA Neurol,2017,74(4):453-458.
［9］　张俊芳,张雨蕾,尹肖睿,等.脑侧支循环在缺血性卒中的研究进展［J］.中国卒中杂志,2018，13（6）:636-641.
［10］　KAMRAN S,BATES V,BAKSHI R,et al.Significance of heyperintenser vessels on FLAIR MRI in acute stroke［J］.Neurology,2000,55(2):265-269.
［11］　CHALELA J A,ALSOP D C,GONZALEZ-ATAVALES J B,et al.Magnetic resonance perfusion imaging in acute is chemis stroke using continuous arterial spin labeling［J］.Stroke,2000,31(3):680-687.
［12］　LOU X,YU S,SCALZO F,et al.Multi-delay ASL can identify leptomeningeal collateral perfusion in endovascular therapy of ischemic stroke［J］.Oncotarget,2017,8(2):2437-2443.

相似文献/References:

[1]赵　迪,张保朝,殷　洁.大脑前循环短暂性脑缺血发作患者大脑中动脉粥样硬化性狭窄高分辨率磁共振形态学分析[J].新乡医学院学报,2017,34(3):209.[doi:10.7683/xxyxyxb.2017.03.014]
　ZHAO Di,ZHANG Bao-chao,YIN Jie.High resolution magnetic resonance morphological analysis of middle cerebral artery atherosclerotic stenosis in patients with transient cerebral ischemic attack[J].Journal of Xinxiang Medical University,2017,34(9):209.[doi:10.7683/xxyxyxb.2017.03.014]

更新日期/Last Update: 2020-09-05