[1]张海洋,宋翠萍,刘 晖,等.人绒毛膜促性腺激素与负压吸引治疗儿童隐匿阴茎术后小阴茎疗效比较[J].新乡医学院学报,2020,37(7):645-647.[doi:10.7683/xxyxyxb.2020.07.0011]
 ZHANG Haiyang,SONG Cuiping,LIU Hui,et al.Comparison of therapeutic effect between human chorionic gonadotropin and vacuum aspiration in the treatment of microcaulia in children with concealed penis after operation[J].Journal of Xinxiang Medical University,2020,37(7):645-647.[doi:10.7683/xxyxyxb.2020.07.0011]
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人绒毛膜促性腺激素与负压吸引治疗儿童隐匿阴茎术后小阴茎疗效比较
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《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
37
期数:
2020年7
页码:
645-647
栏目:
临床研究
出版日期:
2020-07-05

文章信息/Info

Title:
Comparison of therapeutic effect between human chorionic gonadotropin and vacuum aspiration in the treatment of microcaulia in children with concealed penis after operation
作者:
张海洋宋翠萍刘 晖赵 靓饶 旺张远圆
(新乡医学院第一附属医院小儿外科,河南 卫辉 453100)
Author(s):
ZHANG HaiyangSONG CuipingLIU HuiZHAO LiangRAO WangZHANG Yuanyuan
(Department of Pediatric Surgery,the First Affiliated Hospital of Xinxiang Medical University,Weihui 453100,Henan Province,China)
关键词:
隐匿阴茎小阴茎人绒毛膜促性腺激素负压吸引
Keywords:
concealed penismicrocauliahuman chorionic gonadotrophinvacuum aspiration
分类号:
R726.9
DOI:
10.7683/xxyxyxb.2020.07.0011
文献标志码:
A
摘要:
目的 比较人绒毛膜促性腺激素(HCG)与负压吸引治疗儿童隐匿阴茎术后小阴茎的临床效果。方法 选择2016年1月至2019年12月新乡医学院第一附属医院收治的隐匿阴茎术后6个月的小阴茎患儿98例为研究对象,根据治疗方法将患儿分为HCG组和负压吸引组,每组49例。HCG组患儿给予HCG 1 000 U,肌内注射,2周1次,治疗10周,总剂量为5 000 U。负压吸引组患儿给予阴茎负压吸引治疗,每日1次,每次30 min,治疗10 d。分别于治疗前后测量2组患儿阴茎牵伸长度、阴茎松弛长度和阴茎纵径,并计算治疗后患儿阴茎牵伸长度、阴茎松弛长度和阴茎纵径的增长值。结果 2组患儿治疗前阴茎牵伸长度、阴茎松弛长度和阴茎纵径比较差异无统计学意义(P>0.05),2组患儿治疗后阴茎牵伸长度、阴茎松弛长度和阴茎纵径均大于治疗前(P<0.05);治疗后,HCG组患儿阴茎牵伸度、阴茎松弛长度和阴茎纵径大于负压吸引组(P<0.05),HCG组患儿阴茎牵伸长度、阴茎松弛长度及阴茎纵径的增长值均大于负压吸引组(P<0.05)。结论 HCG和负压吸引治疗儿童隐匿阴茎术后小阴茎均有效,但HCG的治疗效果优于负压吸引治疗。
Abstract:
Objective To compare the clinical effect of human chorionic gonadotropin(HCG) and vacuum aspiration in the treatment of microcaulia in children with concealed penis after operation.Methods Ninety-eight children with microcaulia admitted to the First Affiliated Hospital of Xinxiang Medical University from January 2016 to December 2019 were selected as the study objects at 6 months after the operation of concealed penis.The children were divided into HCG group and vacuum aspiration group according to the treatment,with 49 cases in each group.The children in the HCG group were treated with 1 000 U HCG by intramuscular injection,once every two weeks for 10 weeks,the total dose was 5000 U.The children in the vacuum aspiration group were treated with vacuum aspiration once a day for 10 days,30 min per time.The penile stretch length,penile relaxation length and penile longitudinal diameter were measured before and after treatment,and the increments of the penile stretch length,penile relaxation length and penile longitudinal diameter were calculated after treatment.Results There was no significant difference in the penile stretch length,penile relaxation length and penile longitudinal diameter between the two groups before treatment (P>0.05).The penile stretch length,penile relaxation length and penile longitudinal diameter after treatment were greater than those before treatment (P<0.05).After treatment,the penile stretch length,penile relaxation length and penile longitudinal diameter of the children in the HCG group were greater than those in the vacuum aspiration group (P<0.05),and the increments of penile stretch length,penile relaxation length and penile longitudinal diameter in the HCG group were greater than those in the vacuum aspiration group (P<0.05).Conclusion Both HCG and vacuum aspiration are effective in the treatment of microcaulia in children with concealed penis after operation,but the curative effect of HCG is better than that of vacuum aspiration.

参考文献/References:

[1] 张金哲.小儿外科学:下册[M].北京:人民卫生出版社,2018:1401-1402.
[2] KURTOGˇLU S,HATIPOGˇLU N.Micropenis:etiology,diagnosis and treatment approaches[J].J Clin Res Pediatr Endocrinol,2013,5(4):217-223.
[3] 李振武,宋宏程,张潍平,等.先天性隐匿阴茎的分型及治疗探讨[J].临床小儿外科杂志,2018,17(12):894-897.
[4] 杨俊家,王爱和,杨华军,等.不同手术方法治疗小儿隐匿性阴茎的临床效果分析[J].中国妇幼保健,2020,35(6):1073-1075.
[5] 钱静,白明,杨巧芝.影响我国儿童生殖健康常见病诊疗现状分析[J].中国儿童保健杂志,2015,23(8):831-833.
[6] 郭战,杨艳芳,毕建朋,等.改良Brisson术治疗儿童隐匿阴茎[J].中华整形外科杂志,2020,36(1):68-71.
[7] GE W L,ZHU X,XU Y Z,et al.Therapeutic effects of modified Devine surgery for concealed penis in children[J].Asian J surg,2019,42(1):356-361.
[8] 王誉都,李鹏,高亚,等.改良Devine术治疗小儿隐匿性阴茎对患儿术后阴茎长度和生长发育的影响[J].国际泌尿系统杂志,2020,40(1):99-102.
[9] CHEN C,LI N,LUO Y G,et al.Effects of modified penoplasty for concealed penis in children[J].Int Urol Nephrol,2016,48(10):1559-1563.
[10] 马达,陈景琪,钟建华,等.阴茎阴囊角固定术与阴茎根部背侧皮肤固定术治疗小儿隐匿性阴茎疗效比较[J].新乡医学院学报,2019,36(11):1078-1080.
[11] XU D,LU L S,XI L,et al.Efficacy and safety of percutaneous administration of dihydrotestosterone in children of different genetic backgrounds with micropenis[J].J Pediatr Endocrinol Metab,2017,30(12):1285-1291.
[12] SURAMPUDI P,SWERDLOFF R S,WANG C.An update on male hypogonadism therapy[J].Expert Opin Pharmacother,2014,15(9):1247-1264.
[13] 刘波,王霞,陈勇.不同年龄小阴茎儿童的内分泌治疗[J].广东医学,2015,36(10):1579-1581.
[14] 陈超,杨体泉,董淳强,等.人绒毛膜促性腺激素治疗尿道下裂并小阴茎的临床疗效[J].中华实用儿科临床杂志,2017,32(11):821-824.
[15] NERLI R B,GUNTAKA A K,PATNE P B,et al.Penile growth in response to hormone treatment in children with micropenis[J].Indian J Urol,2013,29(4):288-291.
[16] 刘晖,宋翠萍,张海洋,等.负压吸引辅以中药药浴治疗学龄期肥胖儿小阴茎的临床疗效分析[J].中华实用儿科临床杂志,2018,33(7):543-545.
[17] 赵靓,宋翠萍,张海洋,等.负压吸引和外用睾酮霜治疗尿道下裂术后小阴茎的疗效[J].中华实用儿科临床杂志,2020,35(4):297-301.
[18] 班德文,张滨,齐涛,等.负压吸引对阴茎海绵体动脉血流影响的研究[J].中国性科学,2008,17(11):3-4.
[19] 余秋宏,周少虎.负压吸引治疗“阴茎短小”[J].临床泌尿外科杂志,1991,6(2):108.

更新日期/Last Update: 2020-07-05