[1]杨晓亮,范毛川,魏　灿,等.内镜辅助下经尿道柱状水囊前列腺扩开术治疗高龄高危良性前列腺增生疗效观察[J].新乡医学院学报,2020,37(6):570-573.[doi:10.7683/xxyxyxb.2020.06.016]
　YANG Xiaoliang,FAN Maochuan,WEI Can,et al.Effect of endoscope-assisted transurethral columnar balloon dilation of the prostate in the treatment of high-risk elderly patients with benign prostatic hyperplasia[J].Journal of Xinxiang Medical University,2020,37(6):570-573.[doi:10.7683/xxyxyxb.2020.06.016]
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内镜辅助下经尿道柱状水囊前列腺扩开术治疗高龄高危良性前列腺增生疗效观察
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《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
37
期数:
2020年6
页码:
570-573
栏目:
临床研究
出版日期:
2020-06-05

文章信息/Info

Title:
Effect of endoscope-assisted transurethral columnar balloon dilation of the prostate in the treatment of high-risk elderly patients with benign prostatic hyperplasia
作者:
杨晓亮1; 范毛川2; 魏　灿1; 张艳斌1; 席俊华1; 王　伟1; 吴　畏1; 杨振兴1; 井俊峰1; 齐　伟1; 陈华国3
（1.合肥市第二人民医院泌尿外科，安徽　合肥　230011；2.新乡医学院第一附属医院泌尿外科，河南　卫辉　453100；3.同济大学附属上海市第十人民医院急诊科，上海　200072）
Author(s):
YANG Xiaoliang1; FAN Maochuan2; WEI Can1; ZHANG Yanbin1; XI Junhua1; WANG Wei1; WU Wei1; YANG Zhenxing1; JIN Junfeng1; QI Wei1; CHEN Huaguo3
(1.Department of Urology,the Second People′s Hospital of Hefei,Hefei 230011,Anhui Province,China;2.Department of Urology,the First Affiliated Hospital of Xinxiang Medical University,Weihui 453100,Henan Province,China;3.Department of Emergency,the Tenth People′s Hospital of Shanghai Affiliated to Tongji University,Shanghai 200072,China)
关键词:
良性前列腺增生; 高危患者; 经尿道柱状水囊前列腺扩开术; 内镜
Keywords:
benign prostatic hyperplasia; high-risk patient; transurethral columnar balloon dilation of the prostate; endoscope
分类号:
R697+.3
DOI:
10.7683/xxyxyxb.2020.06.016
文献标志码:
A
摘要:
目的　探讨内镜辅助下经尿道柱状水囊前列腺扩开术（EA-TUCBDP）治疗高龄高危良性前列腺增生（BPH）的临床疗效与安全性。方法　回顾性分析2016年11月至2019年8月合肥市第二人民医院收治的31例高龄高危BPH患者的临床资料，所有患者行EA-TUCBDP治疗，分别于手术前和术后3个月对患者进行国际前列腺症状评分（IPSS）和生活质量（QOL）评分，应用尿流率检测仪检测最大尿流率（Qmax），应用经腹超声检测排泄后残留尿量（PVR），并检测患者血清前列腺特异性抗原（PSA）水平；记录患者扩裂手术时间、术中出血量、持续膀胱冲洗时间、术后尿管留置时间、术后住院时间及围术期并发症；所有患者术后随访3～24个月，观察并发症发生情况。结果　31例患者均成功完成手术，扩裂手术时间（41.65±14.30）min，术中出血量（9.19±16.34）mL，持续膀胱冲洗时间（2.00±0.73）d，术后导尿管留置时间（6.94±1.67）d，术后住院时间（10.19±3.96）d。2例术后出血患者采用尿管牵引压迫、药物止血治疗后缓解；拔管后暂时性尿失禁3例，症状均在2周内消失；术后发热1例，给予敏感抗生素治疗后热退。与术前比较，术后3个月患者IPSS评分、QOL评分、PVR显著降低，Qmax显著升高（P＜0.05）；术后3个月患者血清PSA水平与术前比较差异无统计学意义（P＞0.05）。1例患者术后出现逆行射精，术后6个月症状自行缓解；其他患者无并发症发生。结论　EA-TUCBDP治疗BPH安全、有效，具有操作简便、学习曲线短、手术时间短、手术创伤小、术后并发症少、复发率低等优点。
Abstract:
Objective　To investigate the clinical effect and safety of endoscope-assisted transurethral columnar balloon dilation of the prostate (EA-TUCBDP) in the treatment of high-risk elderly patients with benign prostatic hyperplasia(BPH).Methods　The clinical data of 31 high-risk elderly patients with BPH admitted to the Second People′s Hospital of Hefei from November 2016 to August 2019 were analyzed retrospectively.All patients were treated with EA-TUCBDP.Before and three months after operation,the patients were assessed with international prostate symptom score (IPSS) and quality of life (QOL) score,the maximum urine flow rate (Qmax) was measured by uroflowmetry,the postvoid residual (PVR) was measured by transabdominal ultrasound,and the serum prostate specific antigen (PSA) level was measured.The operation time,intraoperative bleeding volume,continuous bladder irrigation time,postoperative catheter retention time,postoperative hospitalization time and perioperative complications were recorded.All patients were followed up for 3-24 months after operation to observe the complications.Results　The operation was successfully completed in 31 patients.The operation time,intraoperative bleeding volume,continuous bladder irrigation time,catheter retention time and the postoperative hospitalization time were (41.65±4.30) min,(9.19±16.34) mL,(2.00±0.73) d,(6.94±1.67) d and (10.19±3.96) d.The two patients with postoperative bleeding were relieved after the treatment of urinary tube compression and drug hemostasis.The symptoms of three cases of temporary urinary incontinence disappeared within two weeks after extubation.The temperature of one patient with postoperative fever recovered after sensitive antibiotic treatment.Compared with before operation,the IPSS score,QOL score and PVR decreased significantly,and the Qmax increased significantly (P<0.05).There was no significant difference in serum PSA level between the three months after operation and before operation (P＞0.05).The retrograde ejaculation occurred in one patients,and the symptoms relieved at six months after operation.No complications occurred in other patients.Conclusion　EA-TUCBDP is safe and effective in the treatment of BPH.It has the advantages of simple operation,short learning curve,short operation time,small surgical trauma,less postoperative complications and low recurrence rate.

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更新日期/Last Update: 2020-06-05