[1]李　鹏,罗瑞华,郭兰伟,等.开放性甲状腺癌手术患者术后出血相关危险因素分析[J].新乡医学院学报,2020,37(3):274-276.[doi:10.7683/xxyxyxb.2020.03.018]
　LI Peng,LUO Ruihua,GUO Lanwei,et al.Analysis of related risk factors of postoperative hemorrhage in patients undergoing open thyroid cancer operation[J].Journal of Xinxiang Medical University,2020,37(3):274-276.[doi:10.7683/xxyxyxb.2020.03.018]
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开放性甲状腺癌手术患者术后出血相关危险因素分析
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《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
37
期数:
2020年3
页码:
274-276
栏目:
临床研究
出版日期:
2020-03-12

文章信息/Info

Title:
Analysis of related risk factors of postoperative hemorrhage in patients undergoing open thyroid cancer operation
作者:
李　鹏1; 罗瑞华1; 郭兰伟2; 李文鹿3; 齐金星1
（1.郑州大学附属肿瘤医院头颈甲状腺外科，河南　郑州　450008；2.郑州大学附属肿瘤医院肿瘤防办中心，河南　郑州　450008；3.郑州大学第一附属医院口腔颌面外科，河南　郑州　450052）
Author(s):
LI Peng1; LUO Ruihua1; GUO Lanwei2; LI Wenlu3; QI Jinxing1
(1.Department of Head Neck and Thyroid Surgery,the Affiliated Cancer Hospital of Zhengzhou University,Zhengzhou 450008,Henan Province,China；2.Department of Cancer Control and Research,the Affiliated Cancer Hospital of Zhengzhou University,Zhengzhou 450008,Henan Province,China；3.Department of Oral and Maxillofacial Surgery,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,Henan Province,China)
关键词:
甲状腺癌; 甲状腺切除术; 术后出血; 危险因素
Keywords:
thyroid carcinoma; thyroidectomy;  postoperative hemorrhage; risk factor
分类号:
R736.1
DOI:
10.7683/xxyxyxb.2020.03.018
文献标志码:
A
摘要:
目的　探讨开放性甲状腺癌手术患者术后出血的相关影响因素，为预防出血导致严重并发症提供参考依据。方法　回顾性分析2014年5月至2019年5月于郑州大学附属肿瘤医院行开放性甲状腺癌手术的2 871例患者的临床资料，采用单因素和多因素logistic回归分析开放性甲状腺癌手术后发生出血的相关危险因素。结果　2 871例行开放性甲状腺癌手术患者中，术后出血41例，术后出血率为1.43%（41/2871）。开放性甲状腺癌手术后出血与手术时间、术中出血量、合并全身系统性疾病（糖尿病、高血压及冠状动脉粥样硬化性心脏病）及合并甲状腺自身免疫性疾病（桥本甲状腺炎、甲状腺功能亢进）有关（P<0.05），与患者年龄、性别、病理类型、T分期、N分期及临床分期无关（P>0.05）。多因素logistic回归分析结果显示，手术时间、术中出血量、颈淋巴结清扫、合并全身系统性疾病（糖尿病、高血压及冠状动脉粥样硬化性心脏）及合并甲状腺自身免疫性疾病（桥本甲状腺炎、甲状腺功能亢进症）是影响甲状腺癌术后出血的相关因素（P<0.05）。结论　手术时间、术中出血量、颈淋巴结清扫、合并全身系统性疾病（糖尿病、高血压及冠状动脉粥样硬化性心脏病）及合并甲状腺自身免疫性疾病（桥本甲状腺炎、甲状腺功能亢进症）是影响甲状腺癌术后出血的危险因素。
Abstract:
Objective　To analysis the related risk factors of postoperative hemorrhage in patients undergoing open thyroid cancer operation and to provide reference for preventing the serious complications caused by hemorrhage.Methods　The data of 2871 patients undergoing open thyroid cancer operation in the Affiliated Cancer Hospital of Zhengzhou University from May 2014 to May 2019 were analyzed respectively.Univariate logistic regression and multivariate logistic regression were used to analyze the risk factors of hemorrhage after open thyroid cancer operation.Results　A total of 41 cases among 2 871 patients had postoperative hemorrhage and the hemorrhage rate was 1.43%.Hemorrhage in the patients undergoing open thyroid cancer operation was related to operation time,intraoperative bleeding volume,neck lymph node dissection,systemic diseases (diabetes,hypertension and coronary heart disease) and autoimmune thyroid diseases (hashimoto thyroiditis and hyperthyroidism) (P<0.05)，but it was not related to age,gender,pathological type,T stage,N stage and clinical stage (P>0.05).Multivariate logistic regression analysis showed that operation time,intraoperative bleeding volume,neck lymph node dissection,systemic diseases (diabetes,hypertension and coronary heart disease) and autoimmune thyroid diseases (hashimoto thyroiditis and hyperthyroidism) are the related factors affecting postoperative hemorrhage of thyroid cancer.Conclusions　The operation time,intraoperative bleeding volume,neck lymph node dissection,systemic diseases (diabetes,hypertension and coronary heart disease) and autoimmune thyroid diseases (hashimoto thyroiditis and hyperthyroidism) are the risk factors affecting postoperative hemorrhage of thyroid cancer.

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更新日期/Last Update: 2020-03-05