[1]李俊艳,郭晓亮,岳　兵,等.急性心力衰竭患者谵妄发生的相关危险因素分析[J].新乡医学院学报,2020,37(3):255-257.[doi:10.7683/xxyxyxb.2020.03.013]
　LI Junyan,GUO Xiaoliang,YUE Bing,et al.Risk factors of delirium in patients with acute heart failure[J].Journal of Xinxiang Medical University,2020,37(3):255-257.[doi:10.7683/xxyxyxb.2020.03.013]
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急性心力衰竭患者谵妄发生的相关危险因素分析
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《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
37
期数:
2020年3
页码:
255-257
栏目:
临床研究
出版日期:
2020-03-12

文章信息/Info

Title:
Risk factors of delirium in patients with acute heart failure
作者:
李俊艳; 郭晓亮; 岳　兵; 侯云涛; 郭云双; 赵红燕; 袁　宇
（新乡医学院第一附属医院心脏重症监护病房，河南　卫辉　453100）
Author(s):
LI Junyan; GUO Xiaoliang; YUE Bing; HOU Yuntao; GUO Yunshuang; ZHAO Hongyan; YUAN Yu
(Cardiac Intensive Care Unit,the First Affiliated Hospital of Xinxiang Medical University,WeiHui 453100,Henan Province,China）
关键词:
谵妄; 急性心力衰竭; 危险因素
Keywords:
delirium; acute heart failure; risk factor
分类号:
R541.6
DOI:
10.7683/xxyxyxb.2020.03.013
文献标志码:
A
摘要:
目的　探讨入住心脏重症监护病房（CCU）的急性心力衰竭（AHF）患者发生谵妄的危险因素，为防治谵妄及改善患者预后提供依据。方法　选择2018年7月至2019年8月新乡医学院第一附属医院CCU收治的AHF患者90例为研究对象，应用重症监护谵妄筛查量表评估患者的谵妄；采取回顾性分析方法，通过临床病历系统收集受试者的临床资料，包括性别、年龄、急性生理学及慢性健康状况评分系统（APACHEⅡ）评分、陈旧性脑梗死(OCI)病史、高血压病史、糖尿病病史、机械通气及血清肌酐、超敏C反应蛋白（hs-CRP）、氨基末端脑钠肽前体(NT-proBNP)水平和左心室射血分数、CCU住院时间等，采用Spearman相关分析、logistic回归分析谵妄发生的危险因素。结果　90例AHF患者CCU住院期间谵妄发生率为26.67%（24/90）。AHF患者谵妄的发生与年龄、APACHE-Ⅱ评分、OCI病史、机械通气、血清hs-CRP、肌酐水平及CCU住院时间有关 (P＜0.05)。Spearman相关性分析结果显示，谵妄的发生与患者APACHEⅡ 评分、年龄、机械通气、CCU住院时间呈正相关（r=0.610、0.542、0.437、0.717,P＜0.05）。多因素logistic回归分析显示，年龄、机械通气、APACHEⅡ 评分、CCU住院时间是谵妄发生的独立危险因素（P＜0.05）。结论　AHF患者谵妄发生率较高，年龄、机械通气、APACHEⅡ评分、CCU住院时间是AHF患者发生谵妄的独立危险因素。
Abstract:
Objective　To explore the risk factors of delirium in patients with acute heart failure (AHF) in the cardiac intensive care unit (CCU),and to provide the basis for preventing delirium and improve the prognosis of the patients.Methods　Ninety patients with AHF in CCU of the First Affiliated Hospital of Xinxiang Medical University from July 2018 to August 2019 were selected as the study subjects.Intensive care delirium screening checklist(ICDSC）was used to evaluate the delirium of patients,and the retrospective analysis method was used to obtain the clinical data of the patients from clinical medical records system,including gender,age,acute physiology and chronic health evaluation system (APACHE II) scores,old cerebral infarction (OCI) history,hypertension history,diabetes history,mechanical ventilation and serum creatinine,hypersensitive C-reactive protein (hs-CRP) and N-terinal fragment of pro-brain natriuretic peptide (NT-proBNP),left ventricular ejection fraction,CCU check-in time and so on.Spearman correlation analysis and logistic regression were used to analyze the risk factors of delirium.Results　Delirium occurred in 24 of 90 AHF patients during stay in the CCU,and the incidence of delirium was 26.67%（24/90）.The occurrence of delirium in patients with AHF was associated with age,APACHE-II score,OCI,mechanical ventilation,the level of serum hs-CRP and creatinine,and hospital stays in CCU (P<0.05).Spearman correlation analysis showed that the occurrence of delirium was positively correlated with patients′ APACHEII score,age,mechanical ventilation,and hospital stays in CCU (r=0.610,0.542,0.437,0.717;P<0.05).Multivariate logistic analysis showed that age,mechanical ventilation,APACHEII score,and hospital stays in CCU were independent risk factors of delirium(P<0.05).Conclusions　Patients with AHF had a high incidence of delirium.The age,mechanical ventilation,disease severity,and hospital stays in CCU were independent risk factors of delirium in patients with AHF.

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更新日期/Last Update: 2020-03-05