[1]齐智慧.血钙对康复期脑卒中患者认知功能的影响[J].新乡医学院学报,2020,37(2):193-195.[doi:10.7683/xxyxyxb.2020.02.022]
　QI Zhihui.Effect of serum calcium on cognitive function of stroke patients during rehabilitation[J].Journal of Xinxiang Medical University,2020,37(2):193-195.[doi:10.7683/xxyxyxb.2020.02.022]
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血钙对康复期脑卒中患者认知功能的影响
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《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
37
期数:
2020年2
页码:
193-195
栏目:
临床研究
出版日期:
2020-02-05

文章信息/Info

Title:
Effect of serum calcium on cognitive function of stroke patients during rehabilitation
作者:
齐智慧
（鹤壁市人民医院神经内科，河南　鹤壁　458030）
Author(s):
QI Zhihui
（Department of Neurology,Hebi People′s Hospital， Hebi 458030,Henan Province,China）
关键词:
脑卒中; 康复期; 血钙; 认知功能
Keywords:
stroke; rehabilitation; calcium; cognitive function
分类号:
R743
DOI:
10.7683/xxyxyxb.2020.02.022
文献标志码:
A
摘要:
目的　探讨血钙对康复期脑卒中患者认知功能的影响。方法　回顾性分析2014年1月至2017年1月鹤壁市人民医院收治的196例康复期脑卒中患者的临床资料，其中合并认知功能障碍98例（认知功能障碍组），认知功能正常98例（认知功能正常组）。采用蒙特利尔认知评估量表（MOCA）评估2组患者的认知功能，全自动生物化学分析仪测定血钙水平，并分析血钙水平与MOCA评分的相关性。结果　认知功能障碍组患者视空间与执行、注意力、命名、定向力和抽象思维评分与认知功能正常组比较差异无统计学意义（P＞0.05）；认知功能障碍组患者短时记忆、语言评分及总分显著低于认知功能正常组（P＜0.05）。认知功能障碍组患者血钙水平均低于认知功能正常组（P＜0.05）。康复期脑卒中患者血钙水平与视空间与执行能力、语言能力、MOCA总分评分呈正相关（r=0.322、0.262、0.294，P＜0.05），与短时记忆、注意力、命名、定向力、抽象思维无相关性（r=0.204、0.121、0.081、0.112、0.180，P>0.05）。结论　康复期脑卒中患者血钙水平与视空间与执行能力和语言能力密切相关，血钙水平越低，认知功能水平越低。
Abstract:
Objective　To explore the influence of serum calcium on the cognitive function of stroke patients during rehabilitation period.Methods　The clinical data of 196 convalescence stroke patients admitted to Hebi People′s Hospital from January 2014 to January 2017 were retrospectively analyzed,including 98 patients with concomitant cognitive dysfunction (cognitive dysfunction group) and 98 patients with normal cognitive function (normal cognitive function group).The Montreal cognitive assessment (MOCA) was used to evaluate the cognitive function of the two groups of patients.The serum calcium level was measured by automatic biochemical analyzer and the correlation between serum calcium level and MOCA score was analyzed.Results　There was no significant difference in visual space and performance,attention,naming,orientation,and abstract thinking scores between the cognitive dysfunction group and the normal cognitive function group (P>0.05).The short-term memory,language score and total score in the cognitive dysfunction group were significantly lower than those in the normal cognitive function group (P<0.05).The blood calcium level of patients in the cognitive dysfunction group was lower than that in the normal cognitive function group (P<0.05).Blood calcium level of patients with stroke during rehabilitation was positively correlated with visual space and executive ability,language ability,and MOCA total score (r=0.322,0.262,0.294；P<0.05),and it was not related to short-term memory,attention,naming,orientation,abstract(r=0.204,0.121,0.081,0.112,0.180；P>0.05).Conclusions　The blood calcium level is closely related to visual space,executive ability and language ability in convalescent stroke patients.The lower the blood calcium level is,the lower the level of cognitive function is.

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更新日期/Last Update: 2020-02-05