[1]周晓敏,孟峻敏.细胞分裂周期蛋白14与细胞分裂周期蛋白25相互作用研究进展[J].新乡医学院学报,2019,36(11):1084-1087.[doi:10.7683/xxyxyxb.2019.11.019]
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细胞分裂周期蛋白14与细胞分裂周期蛋白25相互作用研究进展
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《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
36
期数:
2019年11
页码:
1084-1087
栏目:
综述
出版日期:
2019-11-05

文章信息/Info

作者:
周晓敏1孟峻敏2
(1.内蒙古医科大学研究生学院,内蒙古 呼和浩特 010059;2.内蒙古医科大学附属医院检验科,内蒙古 呼和浩特 010050)
关键词:
细胞分裂周期蛋白14 细胞分裂周期蛋白25周期蛋白依赖性激酶细胞周期
分类号:
R34
DOI:
10.7683/xxyxyxb.2019.11.019
文献标志码:
A
摘要:
细胞分裂周期蛋白14(CDC14)与细胞分裂周期蛋白25(CDC25)是真核细胞生物中广泛表达的一类特殊的高度保守的双重特异性磷酸酶,在真核细胞中发挥稳定生物学作用。CDC14广泛参与有丝分裂、胞质分裂、减数分裂、DNA损伤修复等生理、病理过程,CDC25的表达与细胞增殖和发育有关。真核生物可通过CDC14/CDC25途径调控G2/M期转换从而控制细胞周期进程。目前我国关于CDC14的研究甚少,本文旨在对CDC14的结构、功能以及与CDC25之间的相互作用作一综述。

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更新日期/Last Update: 2019-11-05