[1]郭亚丽,吴纪珍,席 芳,等.Caprini评分联合D-二聚体诊断肺栓塞的价值[J].新乡医学院学报,2019,36(3):275-277.[doi:10.7683/xxyxyxb.2019.03.017]
 GUO Ya-li,WU Ji-zhen,XI Fang,et al.Value of Caprini scores combined with D-dimer for diagnosis of pulmonary embolism[J].Journal of Xinxiang Medical University,2019,36(3):275-277.[doi:10.7683/xxyxyxb.2019.03.017]
点击复制

Caprini评分联合D-二聚体诊断肺栓塞的价值
分享到:

《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
36
期数:
2019年3
页码:
275-277
栏目:
临床研究
出版日期:
2019-03-05

文章信息/Info

Title:
Value of Caprini scores combined with D-dimer for diagnosis of pulmonary embolism
作者:
郭亚丽吴纪珍席 芳孙冠男
(河南省人民医院呼吸与危重症医学科,河南 郑州 450003)
Author(s):
GUO Ya-liWU Ji-zhenXI FangSUN Guan-nan
(Department of Respiratory and Critical Care Medicine,Henan Provincial People′s Hospital,Zhengzhou 450003,Henan Province,China)
关键词:
肺栓塞Caprini评分D-二聚体诊断
Keywords:
pulmonary embolismCaprini scoresD-dimerdiagnosis
分类号:
R563.5
DOI:
10.7683/xxyxyxb.2019.03.017
文献标志码:
A
摘要:
目的 评价Caprini评分联合D-二聚体在诊断肺栓塞中的应用价值。方法 回顾性分析2017年1~12月河南省人民医院收治的134例肺栓塞患者及130例同期住院无肺栓塞患者的临床资料。分析 Caprini评分、D-二聚体及Caprini评分联合D-二聚体诊断肺栓塞的灵敏度、特异度、阳性预测值、阴性预测值、阳性似然比、阴性似然比和约登指数。结果 Caprini评分诊断肺栓塞的灵敏度为88.95%,特异度为84.62%,阳性预测值为85.71%,阴性预测值为88.71%,阳性似然比为5.78,阴性似然比为0.12,约登指数为73.57。D-二聚体诊断肺栓塞的灵敏度为82.84%,特异度为75.38%,阳性预测值为77.62%,阴性预测值为80.99%,阳性似然比为3.36,阴性似然比为0.23,约登指数为58.22。Caprini评分联合D-二聚体诊断肺栓塞的灵敏度为93.28%,特异度为91.54%,阳性预测值为91.91%,阴性预测值为92.97%,阳性似然比为11.03,阴性似然比为0.07,约登指数为84.82。Caprini评分联合D-二聚体诊断肺栓塞的阳性似然比高于Caprini评分、D-二聚体单独诊断(χ2=3.902、14.931,P<0.05),阴性似然比低于Caprini评分、D-二聚体单独诊断(χ2=5.261、16.782,P<0.05)。结论 Caprini评分联合D-二聚体检测诊断肺栓塞的准确性高。
Abstract:
Objective To analyze the value of Caprini scores combined with D-dimer for the diagnosis of pulmonary embolism (PE).Methods The clinical data of 134 patients with PE and 130 patients without PE in the Henan Provincial People′s Hospital from January 2017 to December 2017 was analysed retrospectively.The sensitivity,specificity,positive predictive value,negative predictive value,positive likelihood ratio,negative likelihood ratio and Youden′ index was used to evaluate the value of Caprini scores,D-dimer and Caprini scores combined with D-dimer in the diagnosis of PE.Results The sensitivity,specificity,positive predictive value,negative predictive value,positive likelihood ratio,negative likelihood ratio and Youden′ index values of Caprini scores to diagnose PE was 88.95%,84.62%,85.71%,88.71%,5.78,0.12,73.57,respectively.The sensitivity,specificity,positive predictive value,negative predictive value,positive likelihood ratio,negative likelihood ratio and Youden′ index values of Caprini scores to diagnose PE was 82.84%,75.38%,77.62%,80.99%,3.36,0.23,58.22,respectively.The sensitivity,specificity,positive predictive value,negative predictive value,positive likelihood ratio,negative likelihood ratio and Youden′ index values of Caprini scores combined with D-dimer to diagnose PE was 93.28%,91.54%,91.91%,92.97%,11.03,0.07,84.82.The positive likelihood ratio of Caprini score combined with D-dimer in the diagnosis of PE was higher than that of Caprini score and D-dimer alone (χ2=3.902,14.931;P<0.05),while the negative likelihood ratio was lower than that of Caprini score and D-dimer alone (χ2=5.261,16.782;P<0.05).Conclusion Caprini scores combined with D-dimer highly likely has more accurate predictive value for the diagnosis of PE.

参考文献/References:

[1] 罗小云,张福先.Caprini风险评估模型在综合医院住院患者中的应用[J].中华医学杂志,2017,97(24):1875-1877.
[2] 何国军,符益纲,左其龙,等.D-二聚体在颅内静脉窦血栓形成中的临床意义[J].新乡医学院学报,2016,33(7):620-622.
[3] 中华医学会呼吸病学分会肺栓塞与肺血管病学组,中国医师协会呼吸医师分会肺栓塞与肺血管病工作委员会,全国肺栓塞与肺血管病防治协作组.肺血栓栓塞症诊治与预防指南[J].中华医学杂志,2018,98(14):1060-1087.
[4] BAHL V,HU H M,HENKE P K,et al.A validation study of a retrospective venous thromboembolism risk scoring method[J].Ann Surg,2010,251(2):344-350.
[5] PANNUCCI C J,BAILEY S H,DRESZER G,et al.Validation of the Caprini risk assessment model in plastic and reconstructive surgery patients[J].J Am Coll Surg,2011,212(1):105-112.
[6] SERUYA M,VENTURI M L,IORIO M L,et al.Efficacy and safety of venous thromboembolism prophylaxis in highest risk plastic surgery patients[J].Plast Reconstr Surg,2008,122(6):1701-1708.
[7] HATEF D A,KENKEL J M,NGUYEN M Q,et al.Thromboembolic risk assessment and the efficacy of enoxaparin prophylaxis in excisional body contouring surgery[J].Plast Reconstr Surg,2008,122(1):269-279.
[8] CAPRINI J A,ARCELUS J I,REYNA J J.Effective risk stratification of surgical and nonsurgical patients for venous thromboembolic disease[J].Semin Hematol,2001,38(2 Suppl 5):12-19.
[9] ZAKAI N A,WRIGHT J,CUSHMAN M.Risk factors for venous thrombosis in medical inpatients:validation of a thrombosis risk score[J].J Thromb Haemost,2004,2(12):2156-2161.
[10] GOULD M K,GARCIA D A,WREN S M,et al.Prevention of VTE in nonorthopedic surgical patients:antithrombotic therapy and prevention of thrombosis,9th ed:american college of chest physicians evidence-based clinical practice guidelines[J].Chest,2012,141(2 Suppl):e227S-e277S.
[11] ZHOU H,WAN L,WU X,et al.Validation of a venous thromboembolism risk assessment model in hospitalized chinese patients:a case-control study[J].J Atheroscler Thromb,2014,21(3):261-272.
[12] GOODACRE S,SUTTON A J,SAMPSON F.The value of clinical assessment in the diagnosis of deep vein thrombosis:a meta-analysis[J].ANN Inter Med,2005,143:129-139.

相似文献/References:

[1]王景学.肺栓塞32例临床分析[J].新乡医学院学报,2003,20(03):208.
[2]王景学.肺栓塞32例临床分析[J].新乡医学院学报,2003,20(03):208.
[3]肖文星,石如海,杨娟,等.父子同患急性肺栓塞[J].新乡医学院学报,2008,25(04):397.
[4]刘万周1,张 亮2,程相阁3. 下腔静脉滤器对转子间骨折并下肢深静脉血栓患者围术期肺栓塞的预防效果[J].新乡医学院学报,2015,32(08):777.
[5]陈芳玮,梁彦超,廖 亮,等.慢性阻塞性肺疾病患者肠道菌群分布、血浆N端脑钠肽前体和D-二聚体水平及其合并肺栓塞的相关危险因素分析[J].新乡医学院学报,2020,37(11):1065.[doi:10.7683/xxyxyxb.2020.11.015]
 CHEN Fangwei,LIANG Yanchao,LIAO Liang,et al.Distribution of intestinal flora,plasma levels of N-terminal brain natriuretic peptide precursor and D-dimer in patients with chronic obstructive pulmonary disease and the related risk factors of complicating with pulmonary embolism[J].Journal of Xinxiang Medical University,2020,37(3):1065.[doi:10.7683/xxyxyxb.2020.11.015]
[6]刘志英,顿晓熠,胡文江,等.4种评分法对2型糖尿病患者深静脉血栓形成的预测价值比较[J].新乡医学院学报,2016,33(11):976.[doi:10.7683/xxyxyxb.2016.11.011]
 LIU Zhi-ying,DUN Xiao-yi,HU Wen-jiang,et al.Comparison of the predictive value of four kinds of scoring models for deep vein thrombosis in patients with type 2 diabetes mellitus[J].Journal of Xinxiang Medical University,2016,33(3):976.[doi:10.7683/xxyxyxb.2016.11.011]
[7]杜佳欣,王君君,张曙光.体外膜氧合在高危肺栓塞再灌注治疗中的作用研究进展[J].新乡医学院学报,2023,40(11):1097.[doi:10.7683/xxyxyxb.2023.11.018]
 DU Jiaxin,WANG Junjun,ZHANG Shuguang.Research progress on the role of extracorporeal membrane oxygenation in the reperfusion treatment of high-risk pulmonary embolism[J].Journal of Xinxiang Medical University,2023,40(3):1097.[doi:10.7683/xxyxyxb.2023.11.018]

更新日期/Last Update: 2019-03-05