[1]杨振方.开腹手术史对腹腔镜结肠癌根治术效果的影响[J].新乡医学院学报,2019,36(2):178-180.[doi:10.7683/xxyxyxb.2019.02.020]
　YANG Zhen-fang.Influence of laparotomy history on laparoscopic radical resection of colon cancer[J].Journal of Xinxiang Medical University,2019,36(2):178-180.[doi:10.7683/xxyxyxb.2019.02.020]
点击复制

开腹手术史对腹腔镜结肠癌根治术效果的影响
分享到：

《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
36
期数:
2019年2
页码:
178-180
栏目:
临床研究
出版日期:
2019-02-05

文章信息/Info

Title:
Influence of laparotomy history on laparoscopic radical resection of colon cancer
作者:
杨振方
（驻马店市中心医院胃肠外科，河南　驻马店　463000）
Author(s):
YANG Zhen-fang
（Department of Gastrointestinal Surgery，Zhumadian Central Hospital，Zhumadian 463000，Henan Province，China）
关键词:
结肠癌; 结肠癌根治术; 开腹手术史; 腹腔镜手术
Keywords:
colon cancer; radical resection of colon cancer; laparotomy history; laparoscopic operation
分类号:
R735.+3
DOI:
10.7683/xxyxyxb.2019.02.020
文献标志码:
A
摘要:
目的　探讨开腹手术史对腹腔镜结肠癌根治术效果的影响。方法　选择2013年1月至2016年1月驻马店市中心医院收治的36例有开腹手术史的结肠癌患者为观察组，并选择同期收治的80例无开腹手术史的结肠癌患者为对照组，2组患者均行腹腔镜结肠癌根治术。记录2组患者的手术时间、术中出血量、中转开腹率、清扫淋巴结数目、术后首次排气时间、术后首次进食时间、术后住院时间及并发症；所有患者术后随访2 a，记录无病生存率。结果　观察组患者手术时间长于对照组，术中出血量多于对照组（P<0.05）；2组患者清扫淋巴结数目、术后首次排气时间、首次进食时间及住院时间比较差异均无统计学意义（P>0.05）。观察组和对照组患者中转开腹率分别为19.44%（7/36）、8.75%（7/80），观察组患者中转开腹率高于对照组（χ2=7.627，P<0.05）。观察组和对照组患者并发症发生率分别为22.22%（8/36）、10.00%（8/80），观察组患者并发症发生率高于对照组（χ2=4.856，P<0.05）。观察组和对照组患者术后2 a无病生存率分别为47.22％（17/36）、51.25％（41/80），2组患者术后2 a无病生存率比较差异无统计学意义（χ2=1.856，P>0.05）。结论　开腹手术史会延长腹腔镜结肠癌根治术的手术时间，增加中转开腹手术和术后并发症的风险。
Abstract:
Objective　To investigate the influence of laparotomy history on laparoscopic radical resection of colon cancer.Methods　A total of 36 colon cancer patients with laparotomy history in Zhumadian Central Hospital from January 2013 to January 2016 were selected as observation group，and 80 colon cancer patients without laparotomy history were selected as control group.All patients were performed with laparoscopic radical resection of colon cancer.The operation time，intraoperative bleeding volume，the rate of converting to laparotomy，the number of lymph nodes cleared，postoperative first exhaust time，postoperative first eating time and postoperative hospitalization time and complications were recorded.All patients were followed up for two years to record the disease-free survival rate.Results　The operation time in the observation group was longer than that in the control group，and the intraoperative bleeding volume in the observation group was more than that in the control group （P<0.05）.There was no significant difference in the number of lymph nodes cleared，postoperative first exhaust time，postoperative first eating time and postoperative hospitalization time between the two groups（P>0.05）.The rate of converting to laparotomy in the observation group and the control group was 19.44% （7/36） and 8.75% （7/80），respectively.The rate of converting to laparotomy in the observation group was higher than that in the control group （χ2=7.627，P<0.05）.The incidence of complications in the observation group and the control group was 22.22% （8/36） and 10.00% （8/80），respectively.The incidence of complications in the observation group was higher than that in the control group （χ2=4.856，P<0.05）.The 2-year disease-free survival rate in the observation group and the control group was 47.22% （17/36） and 51.25% （41/80），respectively.There was no significant difference in the 2-year disease-free survival rate between the two groups （χ2=1.856，P>0.05）.Conclusion　The laparotomy history can prolong the operation time of laparoscopic radical resection of colon cancer and increase the risk of converting to laparotomy and complications.

参考文献/References:

［1］　伍雯，秦环龙.膳食结构改变与结肠癌风险相关性的研究进展［J］.肠外与肠内营养，2014，21（1）：55-59.
［2］　杜圣富，夏国园.大肠癌的相关因素和早期症状研究进展［J］.医药导报，2016，35（增刊）：48-50.
［3］　康清杰，向征.结肠癌筛查和诊疗的研究进展［J］.重庆医学，2015，44（28）：4001-4003.
［4］　曹金鹏，计勇，彭翔，等.腹腔镜完整结肠系膜切除术治疗横结肠癌的疗效评价［J］.中华胃肠外科杂志，2017，20（5）：545-549.
［5］　刘嘉林，余小舫，鲍世韵，等.有开腹手术史患者腹腔镜术前超声判断腹腔粘连的价值［J］.中华消化内镜杂志，2006，23（1）：19-22.
［6］　陈新岐，李瑞平，李力波，等.结肠癌行扩大左半结肠切除术中不同吻合方式的疗效比较［J］.新乡医学院学报，2018，35（5）：393-395.
［7］　WANG L，YAN H，LI J，et al.Outcomes of laparoscopic colorectal surgery in patients of previous abdominal surgery：a systemic review and meta-analysis［J］.Hepatogastroenterology，2015，62（138）：273-278.
［8］　TEI M，WAKASUGI M，OMORI T，et al.Single-port laparoscopic colectomy is safe and feasible in patients with previousabdominal surgery［J］.Am J Surg，2015，209（6）：1007-1012.
［9］　潘华，罗洪亮，黄俊，等.既往腹部手术史对行腹腔镜胃癌根治手术影响的Meta分析［J］.中国普通外科杂志，2016，25（4）：565-572.
［10］　SEETAHAL S，OBIRIEZE A，CORNWELL E E，et al.Open abdominal surgery：a risk factor for future laparoscopic surgery［J］.Am J Surg，2015，209（4）：623-626.
［11］　余少鸿，汤荣春，朱磊，等.腹腔手术史结肠癌患者腹腔镜辅助D3根治术效果及手术技巧［J］.中华腔镜外科杂志：电子版，2016，9（3）：165-167.DOI：10.3877/cma.j.issn.1674-6899.2016.03.010.
［12］　李辉，惠广学，戴剑，等.开放性手术与腹腔镜术对结直肠癌患者术后并发症的不同风险因素分析［J］.现代肿瘤医学，2016，24（6）：921-924.

相似文献/References:

[1]结肠癌肝转移的介入性化疗栓塞术.结肠癌肝转移的介入性化疗栓塞术[J].新乡医学院学报,2001,18(01):032.
[2]杨春华,袁亮,郭海峰,等.结肠癌淋巴结转移43例的CT评价[J].新乡医学院学报,2005,22(04):361.
[3]崔　凯１,王　焕２,宰守峰１,等.结肠腺瘤样息肉病基因在结肠癌患者中的突变热点研究[J].新乡医学院学报,2015,32(09):826.
[4]杨振方.纳米碳染色对早期结肠癌内镜黏膜下剥离术后追加手术效果的影响[J].新乡医学院学报,2018,35(11):994.[doi:10.7683/xxyxyxb.2018.11.012]
　YANG Zhen-fang.Effect of nano-carbon staining on additional operation after endoscopic submucosal dissection for early colon cancer[J].Journal of Xinxiang Medical University,2018,35(2):994.[doi:10.7683/xxyxyxb.2018.11.012]
[5]孟　鑫,李振想,姜孝奎.麦冬皂苷B对人结肠癌SW620细胞增殖和凋亡的影响及机制[J].新乡医学院学报,2019,36(12):1110.[doi:10.7683/xxyxyxb.2019.12.003]
　MENG Xin,LI Zhen-xiang,JIANG Xiao-kui.Effect and mechanism of ophiopogonin B on proliferation and apoptosis of human colon cancer SW620 cells[J].Journal of Xinxiang Medical University,2019,36(2):1110.[doi:10.7683/xxyxyxb.2019.12.003]
[6]冯　妮,李晓琳.血清癌胚抗原、糖类抗原199和肿瘤M2型丙酮酸激酶联合检测在结肠癌诊断中的价值[J].新乡医学院学报,2018,35(3):182.[doi:10.7683/xxyxyxb.2018.03.005]
　FENG Ni,LI Xiao-lin.Value of combined detection of serum carcinoembryonic antigen，carbohydrate antigen 199 and tumor M2 pyruvate kinase for the diagnosis of colon cancer[J].Journal of Xinxiang Medical University,2018,35(2):182.[doi:10.7683/xxyxyxb.2018.03.005]
[7]陈新岐,李瑞平,李力波,等.结肠癌行扩大左半结肠切除术中不同吻合方式的疗效比较[J].新乡医学院学报,2018,35(5):393.[doi:10.7683/xxyxyxb.2018.05.009]
　CHEN Xin-qi,LI Rui-ping,LI Li-bo,et al.Comparison of the curative effect of enlarged left hemicolectomy with different coloproctostomy in patients with colon cancer[J].Journal of Xinxiang Medical University,2018,35(2):393.[doi:10.7683/xxyxyxb.2018.05.009]
[8]刘会芳,李　健,韩双印,等.microRNA-145对人结肠癌Caco-2细胞生物学行为的影响[J].新乡医学院学报,2016,33(3):186.[doi:10.7683/xxyxyxb.2016.03.007]
　LIU Hui-fang,LI Jian,HAN Shuang-yin,et al.Effects of microRNA-145 on biological behaviour of colon cancer Caco-2 cells[J].Journal of Xinxiang Medical University,2016,33(2):186.[doi:10.7683/xxyxyxb.2016.03.007]
[9]张　翠,姬明丽.鼻咽癌相关基因6在结肠癌组织中的表达及临床意义[J].新乡医学院学报,2016,33(7):593.[doi:10.7683/xxyxyxb.2016.07.011]
　ZHANG Cui,JI Ming-li.Clinical significance of nasopharyngeal carcinoma associated gene 6 expression in colon carcinoma[J].Journal of Xinxiang Medical University,2016,33(2):593.[doi:10.7683/xxyxyxb.2016.07.011]
[10]王婧媛,谢雨琪,岳凤恺,等.含GATA锌指结构域1对结肠癌细胞迁移的影响[J].新乡医学院学报,2024,(4):309.[doi:10.7683/xxyxyxb.2024.04.002]
　WANG Jingyuan,XIE Yuqi,YUE Fengkai,et al.Effect of GATA zinc finger domain containing 1 on migration of colon cancer cells[J].Journal of Xinxiang Medical University,2024,(2):309.[doi:10.7683/xxyxyxb.2024.04.002]

更新日期/Last Update: 2019-02-05