[1]仝玉珠.腹腔镜下全面分期手术治疗早期卵巢癌疗效观察[J].新乡医学院学报,2018,35(9):804-806.[doi:10.7683/xxyxyxb.2018.09.013]
 TONG Yu-zhu.Clinical effect of laparoscopic radical staged surgery in the treatment of early ovarian cancer[J].Journal of Xinxiang Medical University,2018,35(9):804-806.[doi:10.7683/xxyxyxb.2018.09.013]
点击复制

腹腔镜下全面分期手术治疗早期卵巢癌疗效观察
分享到:

《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
35
期数:
2018年9
页码:
804-806
栏目:
临床研究
出版日期:
2018-09-05

文章信息/Info

Title:
Clinical effect of laparoscopic radical staged surgery in the treatment of early ovarian cancer
作者:
仝玉珠
(许昌市中医院妇产科,河南 许昌 461000)
Author(s):
TONG Yu-zhu
(Department of Gynaecology and Obstetrics,Traditional Chinese Medicine Hospital of Xuchang City,Xuchang 461000,Henan Province,China)
关键词:
全面分期手术腹腔镜卵巢癌
Keywords:
radical staged surgerylaparoscopeovarian cancer
分类号:
R713.6
DOI:
10.7683/xxyxyxb.2018.09.013
文献标志码:
A
摘要:
目的 探讨腹腔镜下全面分期手术治疗早期卵巢癌的临床效果。方法 将2008年3月至2012年3月许昌市中医院手术治疗的86例早期卵巢癌患者分为开腹组(n=38)和腹腔镜组(n=48),开腹组患者给予开腹全面分期手术,腹腔镜组患者给予腹腔镜下全面分期手术,比较2组患者的手术情况、住院时间、术后并发症发生率、复发率及5 a生存率。结果 2组患者手术时间、腹主动脉旁淋巴结切除数、子宫切除例数比较差异无统计学意义(P>0.05);腹腔镜组患者术中出血量低于开腹组(P<0.05),盆腔淋巴结切除数多于开腹组(P<0.05);术后腹腔镜组患者肛门排气时间、术毕至下床时间、引流管留置时间及住院时间显著短于开腹组(P<0.05),疼痛视觉模拟评分低于开腹组(P<0.05)。开腹组和腹腔镜组患者术后并发症发生率分别为21.1%(8/38)和14.6%(7/48),2组患者术后并发症发生率比较差异无统计学意义(χ2=0.622,P>0.05)。全部患者术后随访6~86个月。随访期间,开腹组和腹腔镜组患者复发率分别为15.8%(6/38)和16.7%(8/48),2组患者的复发率比较差异无统计学意义(χ2=0.010,P>0.05);开腹组和腹腔镜组患者5 a生存率分别为84.2%(32/38)和83.3%(40/48),2组患者5 a生存率比较差异无统计学意义(χ2=0.436,P>0.05)。结论 腹腔镜下全面分期手术治疗早期卵巢癌具有出血少、创伤小、术后恢复快等优点。
Abstract:
Objective To explore the clinical effect of laparoscopic radical staged surgery in the treatment of early ovarian cancer.Methods Eighty-six patients with early ovarian cancer who were operated in Traditional Chinese Medicine Hospital of Xuchang City from March 2008 to March 2012 were selected and divided into laparotomy group (38 cases) and laparoscope group (48 cases).The patients in the laparotomy group received routine laparotomy,while the patients in the laparoscope group received laparoscopic radical staged surgery.The conditions of surgery,hospital stays,the rate of postoperative complications,the recurrence rate and the 5-year survival rate of the patients in the two groups were compared.Results There was no significant difference in the operation time,the number of paraaortic lymph node resection and hysterectomy cases between the two groups(P>0.05).The intraoperative blood loss of patients in the laparoscope group was significantly lower than that in the laparotomy group (P<0.05);the number of pelvic lymph node resection was significantly more than that in the laparotomy group (P<0.05).The anus exhaust time,the postoperative leaving bed time,the indwelling time of the abdominal drainage tube and the length of stay in the laparoscope group were significantly shorter,and the score of visual analogue scale was lower than those in the laparotomy group (P<0.05).The rates of postoperative complications in the laparotomy group and the laparoscope group were 21.1%(8/38) and 14.6%(7/48);there was no significant difference in the rate of postoperative complications between the two groups(χ2=0.622,P>0.05).All the patients were followed up for 6-86 months.At the period of follow-up,the recurrence rate of patients in the laparotomy group and the laparoscope group was 15.8%(6/38) and 16.7%(8/48);there was no significant difference in the recurrence rate between the two groups(χ2=0.010,P>0.05).The 5-year survival rate of patients in the laparotomy group and the laparoscope group was 84.2%(32/38) and 83.3%(40/48),there was no significant difference in the 5-year survival rate between the two groups(χ2=0.436,P>0.05).Conclusion Laparoscopic radical staged surgery for early ovarian cancer has the advantages of less bleeding,less trauma and postoperative fast recovery.

参考文献/References:

[1] 王开南,李芳.IL-8-CXCR1/2信号通路与卵巢上皮癌关系的研究进展[J].中国免疫学杂志,2016,32(6):904-906,910.
[2] 彭光彩,王晓雯,易村犍,等.监测外周血SCF对预测c-kit阳性上皮性卵巢癌化疗耐药的临床价值[J].现代妇产科进展,2016,25(12):891-894,899.
[3] SIGNORELLI M,FRUSCIO R,CEPPI L,et al.The role of pelvic and aortic lymphadenectomy at second look surgery in apparent early stage ovarian cancer after inadequate surgical staging followed by adjuvant chemotherapy[J].Gynecol Oncol,2014,132(2):312-315.
[4] DITTO A,MARTINELLI F,LORUSSO D,et al.Fertility sparing surgery in early stage epithelial ovarian cancer[J].J Gynecol Oncol,2014,25(4):320-327.
[5] 朱熠,张国楠.卵巢癌、输卵管癌和腹膜癌FIGO2013分期和临床意义的解读[J].肿瘤预防与治疗,2015,28(5):291-294.
[6] 周夏匀,胡如春,陈燕勤,等.曲马朵超前镇痛对卵巢癌根治术后患者应激反应的影响[J].中国基层医药,2016,23(20):3121-3124,3125.
[7] FAGOTTI A,PERELLI F,PEDONE L,et al.Current recommendations for minimally invasive surgical staging in ovarian cancer[J].Curr Treat Options Oncol,2016,17(1):3.
[8] LAZAROV N,LAZAROV L,LAZAROV S.Laparoscopy and early ovarian cancer[J].Akush Ginekol (Sofiia),2013,52(3):60-62.
[9] NASU K,KAI K,HIRAKAWA T,et al.Retrospective analysis of outcomes of secondary debulking surgery for recurrent epithelial ovarian cancer with favorable prognostic factors[J].J Obstet Gynaecol Res,2014,40(3):791-796.
[10] MATULONIS U A,OZA A M,HO T W,et al.Intermediate clinical endpoints:a bridge between progression-free survival and overall survival in ovarian cancer trials[J].Cancer,2015,121(11):1737-1746.

相似文献/References:

[1]陈赜,陈杰,严想元,等.腹腔镜辅助胃癌根治术治疗早期胃癌疗效观察[J].新乡医学院学报,,():000.
[2]邹心忠.腹腔镜下卵巢良性肿瘤剥除术27例分析[J].新乡医学院学报,2001,18(03):212.
[3]周振华,苏国强,张保峰.开腹胆囊切除术和腹腔镜胆囊切除术并发症的比较[J].新乡医学院学报,2002,19(04):301.
[4]程章林,党铁成.急性炎症期腹腔镜胆囊切除术43例分析 [J].新乡医学院学报,2006,23(01):000.
[5]朱翠兰.腹腔镜下保守手术治疗输卵管妊娠32例 [J].新乡医学院学报,2007,24(03):259.
[6]林凛然,方碧梅.腹腔镜下手术治疗异位妊娠疗效观察[J].新乡医学院学报,2008,25(01):060.
[7]陶桂娥,苏卫华.腹腔镜治疗休克型异位妊娠53例 TitleFilter('chTitle');[J].新乡医学院学报,2010,27(04):401.
[8]刘承利,徐新保,张洪义,等.腹腔镜联合纤维胆道镜胆总管探查取石术22 例[J].新乡医学院学报,2011,28(06):000.
[9]程新豹.腹腔镜联合胆道镜在胆囊结石合并胆总管结石中的应用[J].新乡医学院学报,2012,29(08):606.
[10]刘琛姝,王永莉,潘玉韵.腹腔镜手术和开腹手术在早期卵巢肿瘤分期探查术中的应用效果及术后并发症比较 [J].新乡医学院学报,2012,29(10):795.

更新日期/Last Update: 2018-09-05