[1]杨明月,李晓芳,张红伟,等.硬膜外阻滞分娩镇痛对产妇泌乳素水平的影响[J].新乡医学院学报,2018,35(3):216-218.[doi:10.7683/xxyxyxb.2018.03.014]
　YANG Ming-yue,LI Xiao-fang,ZHANG Hong-wei,et al.Effect of epidural labor analgesia on the prolactin levels of parturient[J].Journal of Xinxiang Medical University,2018,35(3):216-218.[doi:10.7683/xxyxyxb.2018.03.014]
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硬膜外阻滞分娩镇痛对产妇泌乳素水平的影响
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《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
35
期数:
2018年3
页码:
216-218
栏目:
临床研究
出版日期:
2018-03-05

文章信息/Info

Title:
Effect of epidural labor analgesia on the prolactin levels of parturient
作者:
杨明月; 李晓芳; 张红伟; 樊　腾; 徐璐丹; 马闻苛; 秦鹏宇; 岳修勤
（新乡医学院第一附属医院麻醉科，河南　卫辉　453100）
Author(s):
YANG Ming-yue; LI Xiao-fang; ZHANG Hong-wei; FAN Teng; XU Lu-dan; MA Wen-ke; QIN Peng-yu; YUE Xiu-qin
（Department of Anesthesia，the First Affiliated Hospital of Xinxiang Medical University，Weihui 453100，Henan Province，China）
关键词:
硬膜外阻滞; 分娩镇痛; 罗哌卡因; 舒芬太尼; 泌乳素
Keywords:
epidural block; labor analgesia; ropivacaine; sufentanil; prolactin
分类号:
R714.3
DOI:
10.7683/xxyxyxb.2018.03.014
文献标志码:
A
摘要:
目的　探讨硬膜外阻滞分娩镇痛对产妇泌乳素（PRL）水平的影响。方法　选择2016年10月至2017年5月在新乡医学院第一附属医院进行分娩的60例初产妇为研究对象，将产妇分为观察组与对照组，每组30例。观察组产妇给予盐酸罗哌卡因复合枸橼酸舒芬太尼硬膜外阻滞分娩镇痛；对照组产妇不采取任何措施行自然分娩。比较2组产妇的疼痛评分、产程、泌乳量，镇痛前及产后24、48 h血清泌乳素（PRL）水平，产后30 min和24、48 h始动泌乳情况。结果　观察组产妇第1产程活跃期明显短于对照组（P<0.05）；观察组与对照组产妇第1产程潜伏期、第2产程、第3产程比较差异均无统计学意义（P>0.05）。2组产妇镇痛前疼痛评分比较差异无统计学意义（P>0.05）；观察组产妇于宫口开3 cm、宫口开全及胎儿娩出时疼痛评分均低于对照组（P<0.05）。2组产妇镇痛前血清PRL水平比较差异无统计学意义（P>0.05）；观察组产妇产后24、48 h的血清PRL水平显著高于对照组（P<0.05）。观察组产妇产后始动泌乳情况优于对照组（P<0.05）。观察组产妇产后24、48 h的泌乳量显著多于对照组（P<0.05）。结论　硬膜外阻滞分娩镇痛能够减轻产妇疼痛，缩短第1产程的活跃期，增加产妇泌乳素水平，增加产后泌乳量。
Abstract:
Objective　To explore the effect of epidural labor analgesia on the prolactin（PRL） levels of parturient.Methods　Sixty primipara who delivered in the First Affiliated Hospital of Xinxiang Medical University from October 2016 to May 2017 were selected as research object.The parturient were divided into observation group and control group，with 30 cases in each group.The parturient in observation group were given ropivacaine combined with sufentanil for epidural block labor analgesia；the parturient in control group took natural production method without any analgesia method.The pain score，duration of labor，milk yield，serum PRL level before analgesia and 24，48 h postpartum and the number of initial lactation at 30 min，24 h，48 h postpartum of maternal were compared between the two groups.Results　The active period of the first stage of labor of parturient in the observation group was significantly shorter than that in the control group（P<0.05）；there was no statistic difference in the latent period of the first stage of labor，the second stage of labor and the third stage of labor of parturient between the observation group and the control group（P>0.05）.There was no statistic difference in the pain score of parturient between the two groups before analgesia（P>0.05）；the pain score of parturient in observation group was significantly lower than that in the control group at the time point of uterine orifice open 3 cm，uterine orifice full dilatation and fetal disengagement（P< 0.05）.There was no statistic difference in the PRL levels of parturient between the two groups before analgesia（P>0.05）；the PRL level of parturient in observation group was significantly higher than that in the control group at 24，48 h postpartum（P<0.05）.The condition of initial lactation of maternal in the observation group was significantly better than that in the control group（P<0.05）.The milk yield of parturient in observation group was significantly more than that in the control group at 24，48 h postpartum（P<0.05）.Conclusion　Epidural analgesia can reduce the pain of parturient，shorten the active stage of the first stage of labor，increase the level of PRL and increase the milk yield of the postpartum.

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更新日期/Last Update: 2018-03-05