[1]杨 赟,柳 鹏,张子恒,等.以表皮生长因子受体ErbB为靶点的抗体药物研究进展[J].新乡医学院学报,2017,34(10):871-873.[doi:10.7683/xxyxyxb.2017.10.002]
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以表皮生长因子受体ErbB为靶点的抗体药物研究进展
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《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
34
期数:
2017年10
页码:
871-873
栏目:
专题报告
出版日期:
2017-10-05

文章信息/Info

作者:
杨 赟柳 鹏张子恒张鹏飞张 帆吕新彦冯志伟
(新乡医学院基础医学院,河南 新乡 453003)
关键词:
肿瘤免疫治疗抗体药物ErbB蛋白
分类号:
R456R979.1
DOI:
10.7683/xxyxyxb.2017.10.002
文献标志码:
A
摘要:
HTSS〗:ErbB家族蛋白属于跨膜受体酪氨酸激酶,特异性表达于乳腺癌及结直肠癌等细胞表面。在乳腺癌及结直肠癌等癌症的治疗中,以ErbB为靶点的抗体药物显示了有效的抗肿瘤活性。本文综述了ErbB家族蛋白功能特点及针对ErbB家族蛋白的抗体药物最新研究背景及进展,将为开发针对该家族蛋白的新型高效抗体提供借鉴和参考。

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更新日期/Last Update: 2017-10-05