[1]于秀芝,刘海龙,郑 豪,等.骶神经电刺激治疗功能性肛门直肠痛疗效观察[J].新乡医学院学报,2017,34(6):535-537.[doi:10.7683/xxyxyxb.2017.06.023]
 YU Xiu-zhi,LIU Hai-long,ZHENG Hao,et al.Effect of sacral nerve stimulation on functional anorectal pain[J].Journal of Xinxiang Medical University,2017,34(6):535-537.[doi:10.7683/xxyxyxb.2017.06.023]
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骶神经电刺激治疗功能性肛门直肠痛疗效观察
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《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
34
期数:
2017年6
页码:
535-537
栏目:
临床研究
出版日期:
2017-06-05

文章信息/Info

Title:
Effect of sacral nerve stimulation on functional anorectal pain
作者:
于秀芝刘海龙郑 豪谭首海周 森
(驻马店市中心医院肛肠科,河南 驻马店 463000)
Author(s):
YU Xiu-zhiLIU Hai-longZHENG HaoTAN Shou-haiZHOU Sen
(Department of Colorectal Surgery,Zhumadian Central Hospital,Zhumadian 463000,Henan Province,China)
关键词:
骶神经电刺激直肠感觉功能生活质量功能性肛门直肠痛
Keywords:
sacral nerve stimulationrectal sensory functionquality of lifefunctional anorectal pain
分类号:
R657.1
DOI:
10.7683/xxyxyxb.2017.06.023
文献标志码:
A
摘要:
目的 探讨骶神经电刺激(SNS)治疗功能性肛门直肠痛(FAP)的临床效果及其对患者生活质量的影响。方法 选取2013年6月至2015年6月驻马店市中心医院收治的FAP患者125例,按照治疗方式分为药物治疗组(n=42)和SNS组(n=83),药物治疗组患者给予氟哌噻吨美利曲辛治疗,SNS组患者给予SNS治疗,均连续治疗3个月;分别于治疗前后对2组患者进行疼痛视觉模拟评分法(VAS)评分,采用健康调查简表评价患者生活质量;治疗后评定2组患者的临床治疗效果。结果 药物治疗组和SNS组患者治疗总有效率分别为83.3%(35/42)和97.6%(81/83),SNS组患者治疗总有效率显著高于药物治疗组(χ2=6.48,P<0.05)。治疗前2组患者直肠感觉功能比较差异无统计学意义(P>0.05),治疗后2组患者直肠感觉功能显著优于治疗前(P<0.05);治疗后SNS组患者直肠感觉功能显著优于药物治疗组(P<0.05)。治疗前2组患者生活质量评分比较差异无统计学意义(P>0.05),治疗后2组患者生活质量评分显著高于治疗前(P<0.05);治疗后,SNS组患者生理功能、躯体疼痛、总体健康、社会功能、情感职能、精神健康及活力评分均显著高于药物治疗组(P<0.05),但2组患者生理职能评分比较差异无统计学意义(P>0.05)。结论 SNS可以显著改善FAP患者直肠感觉功能和生活质量。
Abstract:
Objective To investigate the clinical effect of sacral nerve stimulation(SNS) in the treatment of functional anorectal pain (FAP) and its influence on the quality of life of patients.Methods A total of 125 patients with FAP were selected from June 2013 to June 2015 in Zhumadian Central Hospital.The patients were divided into medication group (n=42) and SNS group (n=83) according to the treatment method.The patients in the medication group were treated with flupentixol-melitracen,and the patients in SNS group were treated with SNS for three months.The pain score was evaluated by visual analogue scales (VAS),and the quality of life was evaluated by the MOS item short from health survey in the two groups before and after treatment.The clinical curative effect of the patients in the two groups was evaluated after treatment.Results The total effective rate in the medication group and SNS group was 83.3% (35/42) and 97.6% (81/83) respectively,the total effective rate in the SNS group was significantly higher than that in the medication group (χ2=6.48,P<0.05).There was no significant difference in rectal sensory function between the two groups before treatment (P>0.05).The rectal sensory function after treatment was significantly better than that before treatment in the two groups (P<0.05).The rectal sensory function in the SNS group was significantly better than that in the medication group after treatment(P<0.05).There was no significant difference in quality of life between the two groups before treatment (P>0.05).The scores of quality of life after treatment were significantly higher than those before treatment in the two groups (P<0.05).The scores of physiological function,body pain,general health,social function,emotional function,mental health and vitality in the SNS group were significantly higher than those in the medication group after treatment (P<0.05);but there was no significant difference in physiological function score between the two groups (P>0.05).Conclusion SNS can significantly improve the rectal sensory function and the quality of life in patients with FAP.

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更新日期/Last Update: 2017-06-05