[1]李万华,刘　艳,葛燕萍,等.康复新液联合早期肠内营养在防治危重症患者应激性溃疡出血中的应用[J].新乡医学院学报,2016,33(10):911-912.[doi:10.7683/xxyxyxb.2016.10.020]
　LI Wan-hua,LIU Yan,GE Yan-ping,et al.Clinical application of Kangfuxin liquid combined with early enteral nutrition in the prevention and treatment of critically ill patients with stress ulcer bleeding[J].Journal of Xinxiang Medical University,2016,33(10):911-912.[doi:10.7683/xxyxyxb.2016.10.020]
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康复新液联合早期肠内营养在防治危重症患者应激性溃疡出血中的应用
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《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
33
期数:
2016年10
页码:
911-912
栏目:
临床研究
出版日期:
2016-10-05

文章信息/Info

Title:
Clinical application of Kangfuxin liquid combined with early enteral nutrition in the prevention and treatment of critically ill patients with stress ulcer bleeding
作者:
李万华; 刘　艳; 葛燕萍; 张　伟
（开封市第二人民医院急诊科，河南　开封　475000）
Author(s):
LI Wan-hua; LIU Yan; GE Yan-ping; ZHANG Wei
(Department of Emergency,the Second People′s Hospital of Kaifeng City,Kaifeng 475000,Henan Province,China)
关键词:
肠内营养; 应激性溃疡出血; 并发症; 康复新液
Keywords:
enteral nutrition; stress ulcer bleeding; complication; Kangfuxin liquid
分类号:
R656.6+2
DOI:
10.7683/xxyxyxb.2016.10.020
文献标志码:
A
摘要:
目的　探析康复新液联合早期肠内营养防治危重症患者应激性溃疡出血的临床效果。方法　将2013年7月至2015年4月开封市第二人民医院收治的96例危重症患者分为观察组和对照组，每组48例。2组患者均给予常规综合治疗，并在24 h内实施肠内营养支持，观察组患者在肠内营养液内添加康复新液；观察2组患者治疗1、4、7 d 后胃液酸减度（pH）值变化及治疗7 d后应激性溃疡出血发生率。结果　治疗1 d后2组患者胃液pH值比较差异无统计学意义（P>0.05）；治疗4、7 d后观察组患者胃液pH值显著高于对照组（P<0.05）。治疗7 d后，观察组患者发生应激性溃疡出血1例（2.1%），对照组发生9例（18.8%），观察组患者应激性溃疡出血发生率显著低于对照组（P<0.05）。结论　含康复新液的早期肠内营养能提高危重症患者胃液pH值，有效减少应激性溃疡出血的发生。
Abstract:
Objective　To explore the clinical effect of Kangfuxin liquid combined with early enteral nutrition in the prevention and treatment of critically ill patients with stress ulcer bleeding.Methods　Ninty-six critically ill patients in the Second People′s Hospital of Kaifeng City were selected from July 2013 to April 2015 and divided into observation group and control group,with 48 patients in each group.All patients were given routine comprehensive therapy and enteral nutrition support in 24 hours;based on these,the patients in observation group were given Kangfuxin liquid.The changes of power of hydrogen(pH) value of gastric juice of patients at 1 day,4,7 days after treatment and the incidence of stress ulcer bleeding of patients at 7 days after treatment were observed in the both groups.Results　There was no statistic difference of pH value of gastric juice of patients between the two groups at one day after treatment（P>0.05）.The pH value of gastric juice of patients in the observation group was significantly higher than that in the control group at 4,7 days after treatment(P<0.05).The incidence of stress ulcer bleeding of patients in observation group was 2.1%(1/48),which was significantly lower than that in the control group (18.8%,9/48) （P<0.05）.Conclusion　Kangfuxin liquid combined with early enteral nutrition therapy can increase the pH value of gastric juice and reduce the incidence of the stress ulcer bleeding of critically ill patients.

参考文献/References:

［1］　范玉梅,吴修凤.早期肠内营养干预对预防高血压脑出血患者应激性溃疡的作用［J］.中国实用神经疾病杂志,2014,17(8):50-51.
［2］　韩晓丽,薛梅,丁燕,等.探讨质子泵抑制剂和早期肠内营养支持的配伍治疗对重症脑卒中患者应激性溃疡的防治作用［J］.兵团医学,2015,45(3):58-59.
［3］　刘青润.危重病患者早期肠内营养预防应激性溃疡的观察及护理［J］.大家健康:学术版,2014,8(18):244-245.
［4］　季占锋.早期肠内营养预防特重型颅脑损伤并发上消化道出血［J］.中国医学创新,2014,11(8):24-26.
［5］　摆斌,黄鹿.质子泵抑制剂联合早期肠内营养防治脑卒中应激性溃疡临床研究［J］.中国实用神经疾病杂志,2015,18(5):14-16.
［6］　何秀邦.ICU病人早期肠内营养支持治疗与应激性溃疡的预防及护理［J］.哈尔滨医药,2014,34(6):413-414.

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更新日期/Last Update: 2016-10-05