[1]陈　芳,杨　玲,王晓明,等.不同频率重复经颅磁刺激治疗恢复期脑梗死患者疗效观察[J].新乡医学院学报,2016,33(6):480-482.[doi:10.7683/xxyxyxb.2016.06.009]
　CHEN Fang,YANG Ling,WANG Xiao-ming,et al.Effect of different frequency repetitive transcranial magnetic stimulation in treatment of convalescence cerebral infarction[J].Journal of Xinxiang Medical University,2016,33(6):480-482.[doi:10.7683/xxyxyxb.2016.06.009]
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不同频率重复经颅磁刺激治疗恢复期脑梗死患者疗效观察
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《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
33
期数:
2016年6
页码:
480-482
栏目:
临床研究
出版日期:
2016-06-05

文章信息/Info

Title:
Effect of different frequency repetitive transcranial magnetic stimulation in treatment of convalescence cerebral infarction
作者:
陈　芳1; 杨　玲1; 王晓明2; 詹　成1; 王相明1; 朱　晨1; 李光宗1; 王　琰1
（1.攀枝花市中心医院神经内科，四川　攀枝花　617000；2.川北医学院附属医院神经内科，四川 　南充　637000）
Author(s):
CHEN Fang1; YANG Ling1; WANG Xiao-ming2; ZHAN Cheng1; WANG Xiang-ming1; ZHU Chen1; LI Guang-zong1; WANG Yan1
（1.Department of Neurology，the Central Hospital of Panzhihua City，Panzhihua 617000，Sichuan Province，China；2.Department of Neurology，the Affiliated Hospital of North Sichuan Medical College，Nanchong 637000，Sichuan Province，China）
关键词:
脑梗死; 经颅磁刺激; 运动功能; 康复治疗; 运动诱发电位
Keywords:
cerebral infarction; transcranial magnetic stimulation; motor function; rehabilitative treatment; motor evoked potential
分类号:
R743.33
DOI:
10.7683/xxyxyxb.2016.06.009
文献标志码:
A
摘要:
目的　探讨不同频率重复经颅磁刺激（rTMS）治疗脑梗死（CI）恢复期患者的临床效果。方法　选择2009年12月至2011年1月在川北医学院附属医院接受重复rTMS治疗的CI恢复期患者96例，按治疗方法分为高频组（高频rTMS）、低频组（低频rTMS）和假刺激组，每组32例，对3组患者治疗前后的运动功能Fugl-Meyer评定量表（FMA）评分、Barthel指数（BI）、中枢运动传导时间（CMCT）及运动诱发电位（MEP）潜伏期进行比较。结果　治疗前3组患者FMA评分、BI、MEP潜伏期及CMCT比较差异均无统计学意义（P>0.05）。治疗后3组患者的FMA评分、BI显著高于治疗前（P<0.05），而MEP潜伏期及CMCT显著短于治疗前（P<0.05）。治疗后高频组和低频组患者的FMA评分及BI显著高于假刺激组（P<0.05），治疗后高频组和低频组患者的MEP潜伏期和CMCT均显著短于假刺激组（P<0.05）。治疗后高频组和低频组患者FMA评分、BI、MEP潜伏期及CMCT比较差异均无统计学意义（P>0.05）。结论　高、低频rTMS均可以显著促进CI患者运动功能恢复，且二者效果相当。
Abstract:
Objective　To investigate the different frequency repetitive transcranial magnetic stimulation（rTMS） in treatment of convalescence cerebral infarction（CI）.Methods　Ninety-six patients with convalescence CI at recovery stage were selected in the Affiliated Hospital of North Sichuan Medical College from December 2009 to January 2011.The patients were divided into high frequency group（high frequency rTMS），low frequency group（low frequency rTMS） and sham stimulation group，thirty-two patients in each group.The Fugl-Meyer assessment（FMA） score of motor function，Barthel index（BI），central motor conduction time（CMCT） and motor evoked potential（MEP） latency were compared among the three groups before and after treatment.Results　There was no significant difference in FMA score，BI，MEP latency and CMCT among the three groups before treatment（P>0.05）.The FMA score and BI after treatment were significantly higher than those before treatment（P<0.05），and the MEP latency and CMCT after treatment were significantly shorter than those before treatment in the three groups（P<0.05）.The FMA score and BI in the high frequency group and low frequency group were significantly higher than those in the sham stimulation group after treatment（P<0.05）.The MEP latency and CMCT in the high frequency group and low frequency group were significantly shorter than those in the sham stimulation group after treatment（P<0.05）.There was no significant difference in FMA score，BI，MEP latency and CMCT between the high frequency group and low frequency group after treatment（P>0.05）.Conclusion　High and low frequency rTMS can significantly promote the recovery of motor function in patients with CI，and the effect is equivalent.

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更新日期/Last Update: 2016-06-05