[1]陈红丽,秦靖雯,南文滨,等.多功能化乳酸-羟基乙酸共聚物纳米粒作为抗肿瘤药物载体研究进展[J].新乡医学院学报,2016,33(5):349-351.[doi:10.7683/xxyxyxb.2016.05.001]
　CHEN Hongli,QIN Jingwen,NAN Wenbin,et al.Research progress of multifunctional lactic acid glycolic acid copolymer nanoparticles as antitumor drug carriers[J].Journal of Xinxiang Medical University,2016,33(5):349-351.[doi:10.7683/xxyxyxb.2016.05.001]
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多功能化乳酸-羟基乙酸共聚物纳米粒作为抗肿瘤药物载体研究进展
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《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
33
期数:
2016年5
页码:
349-351
栏目:
国家自然科学基金专题述评
出版日期:
2016-05-05

文章信息/Info

Title:
Research progress of multifunctional lactic acid glycolic acid copolymer nanoparticles as antitumor drug carriers
作者:
陈红丽; 秦靖雯; 南文滨; 王永学; 魏向娟; 郏亚静
（新乡医学院生命科学技术学院，河南省干细胞与生物治疗工程技术研究中心，河南　新乡　453003）
Author(s):
CHEN Hongli; QIN Jingwen; NAN Wenbin; WANG Yongxue; WEI Xiangjuan; JIA Yajing
关键词:
乳酸-羟基乙酸共聚物; 多功能; 纳米粒; 肿瘤
分类号:
R979.1
DOI:
10.7683/xxyxyxb.2016.05.001
文献标志码:
A
摘要:
乳酸-羟基乙酸共聚物(PLGA)是被美国食品药品管理局批准的药用辅料，是少数最为成熟的体内降解性聚合物之一。PLGA纳米粒作为抗肿瘤药物载体是近年来药物输送体系的研究热点，但是单一的PLGA纳米载体在应用中存在一定局限性，对PLGA纳米粒进行相应的修饰及复合其他聚合物，赋予其多种功能，可明显克服其缺点，达到扩大其应用范围的作用。本文就近年来多功能化PLGA纳米粒的种类以及用于肿瘤诊疗中的研究进行总结。

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更新日期/Last Update: 2016-05-05