[1]张亚矗.结外自然杀伤/T细胞淋巴瘤的治疗研究进展[J].新乡医学院学报,2024,(4):397-400.[doi:10.7683/xxyxyxb.2024.04.019]
 ZHANG Yachu.Research progress in the treatment of extranodal natural killer/T-cell lymphoma[J].Journal of Xinxiang Medical University,2024,(4):397-400.[doi:10.7683/xxyxyxb.2024.04.019]
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结外自然杀伤/T细胞淋巴瘤的治疗研究进展
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《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
期数:
2024年4
页码:
397-400
栏目:
综述
出版日期:
2024-04-05

文章信息/Info

Title:
Research progress in the treatment of extranodal natural killer/T-cell lymphoma
作者:
张亚矗
(贵州医科大学临床医学院,贵州 贵阳 550000)
Author(s):
ZHANG Yachu
(College of Clinical Medicine,Guizhou Medical University,Guiyang 550000,Guizhou Province,China)
关键词:
结外自然杀伤/T细胞淋巴瘤复发/难治造血干细胞移植靶向治疗
Keywords:
extranodal natural killer/T-cell lymphomarecurrent/refractoryhematopoietic stem cell transplantationtargeted therapy
分类号:
R73
DOI:
10.7683/xxyxyxb.2024.04.019
文献标志码:
A
摘要:
结外自然杀伤/T细胞淋巴瘤(ENKTCL)是一种少见的与EB病毒感染相关的恶性肿瘤,具有较强的侵袭性。目前,对于晚期或复发/难治性ENKTCL,常规推荐使用含左旋门冬酰胺酶的非蒽环类药物联合其他药物进行化学治疗,但长期生存率仍较低。近年来,造血干细胞移植、免疫治疗和靶向治疗受到了广泛关注,为ENKTCL的治疗提供了新的选择。本文就造血干细胞移植、免疫治疗和靶向治疗在ENKTCL治疗中的应用进展进行综述。
Abstract:
Extranodal natural killer/T-cell lymphoma (ENKTCL) is a rare malignant tumor associated with EB virus infection,with strong invasiveness.At present,for advanced or relapsed/refractory ENKTCL,it is recommended to use non-anthracycline drugs containing L-asparaginase in combination with other drugs for chemotherapy,but the long-term survival rate is still low.In recent years,hematopoietic stem cell transplantation,immunotherapy and targeted therapy have received widespread attention,providing new options for the treatment of ENKTCL.This article reviews the therapeutic progress of hematopoietic stem cell transplantation,immunotherapy and targeted therapy in ENKTCL.

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更新日期/Last Update: 2024-04-05