[1]张雪儿,郑 娜,梁紫君,等.微RNA在血管性认知障碍中的作用研究进展[J].新乡医学院学报,2021,38(9):897-900.[doi:10.7683/xxyxyxb.2021.09.022]
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微RNA在血管性认知障碍中的作用研究进展
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《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
38
期数:
2021年9
页码:
897-900
栏目:
综述
出版日期:
2021-09-05

文章信息/Info

作者:
张雪儿1郑 娜2梁紫君1安红伟2
(1.广西中医药大学研究生院,广西 南宁 530200;2.柳州市中医医院神经内科,广西 柳州 545001)
关键词:
血管性认知障碍微RNA认知功能
分类号:
R749.13
DOI:
10.7683/xxyxyxb.2021.09.022
文献标志码:
A
摘要:
血管性认知障碍(VCI)是指脑血管疾病导致的认知功能障碍,即由于各种脑血管疾病和血管危险因素引起的认知功能下降。VCI包括非痴呆型血管认知障碍、血管性痴呆和混合性痴呆。微RNA(miRNA)是一种通过靶向mRNA转录调控基因表达的非编码小RNA,其参与各种疾病的发生和进展,包括血管性疾病。目前,越来越多的研究表明,miRNA与VCI密切相关,而且与学习记忆、空间记忆亦相关,miRNA的高表达可能会引起认知能力的下降。但miRNA在 VCI发病过程中的作用机制尚未完全明了。本文主要对miRNA在VCI发生、发展中的作用以及miRNA在VCI早期诊断与治疗的作用研究进展进行综述。

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更新日期/Last Update: 2021-09-05